sydney blood bank cohort
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2011 ◽  
Vol 6 (3) ◽  
pp. 151-156 ◽  
Author(s):  
John Zaunders ◽  
Wayne B Dyer ◽  
Melissa Churchill

2003 ◽  
Vol 34 (5) ◽  
pp. 445-453 ◽  
Author(s):  
Katherine Kedzierska ◽  
Melissa Churchill ◽  
Clare L. V. Maslin ◽  
Rula Azzam ◽  
Philip Ellery ◽  
...  

2001 ◽  
Vol 22 (3) ◽  
pp. 263-270 ◽  
Author(s):  
M.-R Birch ◽  
J.C Learmont ◽  
W.B Dyer ◽  
N.J Deacon ◽  
J.J Zaunders ◽  
...  

1999 ◽  
Vol 15 (16) ◽  
pp. 1433-1439 ◽  
Author(s):  
David Rhodes ◽  
Ajantha Solomon ◽  
Wayne Bolton ◽  
Jeanette Wood ◽  
John Sullivan ◽  
...  

1999 ◽  
Vol 9 (7) ◽  
pp. 436-440 ◽  
Author(s):  
Larissa B Mcintyre ◽  
Andrew F Geczy ◽  
Wayne B Dyer ◽  
Jennifer C Learmont ◽  
John S Sullivan

1999 ◽  
Vol 340 (22) ◽  
pp. 1715-1722 ◽  
Author(s):  
Jennifer C. Learmont ◽  
Andrew F. Geczy ◽  
John Mills ◽  
Lesley J. Ashton ◽  
Camille H. Raynes-Greenow ◽  
...  

1999 ◽  
Vol 73 (1) ◽  
pp. 436-443 ◽  
Author(s):  
Wayne B. Dyer ◽  
Graham S. Ogg ◽  
Marie-Ange Demoitie ◽  
Xia Jin ◽  
Andrew F. Geczy ◽  
...  

ABSTRACT Proposals for the use of live attenuated human immunodeficiency virus (HIV) type 1 (HIV-1) as a vaccine candidate in humans have been based on the protection afforded by attenuated simian immunodeficiency virus in the macaque model. Although it is not yet known if this strategy could succeed in humans, a study of the Sydney Blood Bank Cohort (SBBC), infected with an attenuated HIV-1 quasispecies with natural nef and nef/long terminal repeat deletions for up to 17 years, could provide insights into the long-term immunological consequences of living with an attenuated HIV-1 infection. In this study, HIV-specific cytoxic T-lymphocyte (CTL) responses in an SBBC donor and six recipients were examined over a 3-year period with enzyme-linked immunospot, tetrameric complex binding, direct CTL lysis, and CTL precursor level techniques. Strong HIV-specific CTL responses were detected in four of seven patients, including one patient with an undetectable viral load. Two of seven patients had weak CTL responses, and in one recipient, no HIV-specific CTLs were detected. High levels of circulating effector and memory HIV-specific CTLs can be maintained for prolonged periods in these patients despite very low viral loads.


1998 ◽  
Vol 14 (9) ◽  
pp. 811-814 ◽  
Author(s):  
ROBERT OELRICHS ◽  
ANNA TSYKIN ◽  
DAVID RHODES ◽  
AJANTHA SOLOMON ◽  
ANNE ELLETT ◽  
...  

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