Identification of a New Recipient in the Sydney Blood Bank Cohort: A Long-Term HIV Type 1-Infected Seroindeterminate Individual

1999 ◽  
Vol 15 (16) ◽  
pp. 1433-1439 ◽  
Author(s):  
David Rhodes ◽  
Ajantha Solomon ◽  
Wayne Bolton ◽  
Jeanette Wood ◽  
John Sullivan ◽  
...  
Keyword(s):  
Blood Bank ◽  
Sydney Blood Bank Cohort ◽  
Hiv Type 1

Sequence Note: Genomic Sequence of HIV Type 1 from Four Members of the Sydney Blood Bank Cohort of Long-Term Nonprogressors

1998 ◽  
Vol 14 (9) ◽  
pp. 811-814 ◽  
Author(s):  
ROBERT OELRICHS ◽  
ANNA TSYKIN ◽  
DAVID RHODES ◽  
AJANTHA SOLOMON ◽  
ANNE ELLETT ◽  
...  
Keyword(s):  
Genomic Sequence ◽  
Blood Bank ◽  
Sydney Blood Bank Cohort ◽  
Hiv Type 1

scholarly journals Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected with nef-Defective HIV Type 1

1999 ◽  
Vol 73 (1) ◽  
pp. 436-443 ◽  
Author(s):  
Wayne B. Dyer ◽  
Graham S. Ogg ◽  
Marie-Ange Demoitie ◽  
Xia Jin ◽  
Andrew F. Geczy ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Lymphocyte ◽  
Blood Bank ◽  
Specific Ctls ◽  
Sydney Blood Bank Cohort ◽  
Immunodeficiency Virus ◽  
Hiv Type 1 ◽  
Hiv 1 ◽  
Ctl Responses

ABSTRACT Proposals for the use of live attenuated human immunodeficiency virus (HIV) type 1 (HIV-1) as a vaccine candidate in humans have been based on the protection afforded by attenuated simian immunodeficiency virus in the macaque model. Although it is not yet known if this strategy could succeed in humans, a study of the Sydney Blood Bank Cohort (SBBC), infected with an attenuated HIV-1 quasispecies with natural nef and nef/long terminal repeat deletions for up to 17 years, could provide insights into the long-term immunological consequences of living with an attenuated HIV-1 infection. In this study, HIV-specific cytoxic T-lymphocyte (CTL) responses in an SBBC donor and six recipients were examined over a 3-year period with enzyme-linked immunospot, tetrameric complex binding, direct CTL lysis, and CTL precursor level techniques. Strong HIV-specific CTL responses were detected in four of seven patients, including one patient with an undetectable viral load. Two of seven patients had weak CTL responses, and in one recipient, no HIV-specific CTLs were detected. High levels of circulating effector and memory HIV-specific CTLs can be maintained for prolonged periods in these patients despite very low viral loads.

Comparable Biological and Molecular Determinants in HIV Type 1-Infected Long-Term Nonprogressors and Recently Infected Individuals

1997 ◽  
Vol 13 (4) ◽  
pp. 337-341 ◽  
Author(s):  
CLAUDIA BALOTTA ◽  
PATRIZIA BAGNARELLI ◽  
CHIARA RIVA ◽  
ANNA VALENZA ◽  
SPINELLO ANTINORI ◽  
...  
Keyword(s):  
Molecular Determinants ◽  
Hiv Type 1

scholarly journals Long‐Term Efficacy of Routine Access to Antiretroviral‐Resistance Testing in HIV Type 1–Infected Patients: Results of the Clinical Efficacy of Resistance Testing Trial

2004 ◽  
Vol 38 (5) ◽  
pp. 723-730 ◽  
Author(s):  
Scott A. Wegner ◽  
Mark R. Wallace ◽  
Naomi E. Aronson ◽  
Sybil A. Tasker ◽  
David L. Blazes ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Resistance Testing ◽  
Term Efficacy ◽  
Testing Trial ◽  
Antiretroviral Resistance ◽  
Hiv Type 1

scholarly journals Molecular Epidemiology Reveals Long‐Term Changes in HIV Type 1 Subtype B Transmission in Switzerland

2010 ◽  
Vol 201 (10) ◽  
pp. 1488-1497 ◽  
Author(s):  
Roger D. Kouyos ◽  
Viktor von Wyl ◽  
Sabine Yerly ◽  
Jürg Böni ◽  
Patrick Taffé ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Subtype B ◽  
Long Term Changes ◽  
Hiv Type 1

Mutations in the HIV Type 1 Integrase of Patients Receiving Long-Term Dideoxynucleoside Therapy Do Not Confer Resistance to Zidovudine

2000 ◽  
Vol 16 (14) ◽  
pp. 1417-1422 ◽  
Author(s):  
André A. Pilon ◽  
Chistophe Marchand ◽  
Mark F. Kavlick ◽  
Kamini Bajaj ◽  
Joshua Owen ◽  
...  
Keyword(s):  
Hiv Type 1

HIV Type 1 V3 Variation Dynamicsin Vivo: Long-Term Persistence of Non-Syncytium-Inducing Genotypes and Transient Presence of Syncytium-Inducing Genotypes during the Course of Progressive AIDS

1997 ◽  
Vol 13 (18) ◽  
pp. 1597-1609 ◽  
Author(s):  
SETSUKO IDA ◽  
HIROYUKI GATANAGA ◽  
TATSUO SHIODA ◽  
YOSHIYUKI NAGAI ◽  
NOBUYUKI KOBAYASHI ◽  
...  
Keyword(s):  
Hiv Type 1
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