Electrochemical Detection of a Local Anesthetic Dibucaine at Arrays of Liquid|Liquid MicroInterfaces

Electrochemical characterization and detection of protonated dibucaine (DIC+) at microinterface array across water|1,6-dichlorohexane were performed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Some thermodynamic parameters of dibucaine, such as the standard transfer potential, the Gibbs energy of transfer and the partition coefficient, were estimated by CV. In addition to the analytical parameters, the impact of bovine serum albumin (BSA) on dibucaine detection (in artificial serum matrices) was also investigated. DPV was applied to detect a lower concentration of DIC+, resulting in a detection limit of 0.9 ± 0.06 µM. While the presence of BSA affected CV, demonstrated as reduced current responses, DPV was confirmed to be an efficient method for lowering concentrations of the dibucaine detection in the artificial serum matrix in the presence of BSA, with a limit of detection (LOD) of 1.9 ± 0.12 µM.

Studies on Thermodynamic Dissociation Constants of 2,2′-Bipyridine and 1,10-Phenanthroline in Acetonitrile + Water Mixtures and Gibbs Energy of Transfer of Hydrogen Ions from Water to Acetonitrile + Water Mixtures

The thermodynamic dissociation constants for isoelectric reactions of the type LHAttempts were made to understand the basicity and structuredness of acetonitrile + water mixtures from a comparative study of Δ

Studies on the Solubility and Dissociation Constants of Oxalic Acid in Aquo + Ethanolic Mixtures and Determination of Single-Ion Gibbs Energy of Transfer from Aqueous to Aquo + Ethanolic Mixtures

The dissociation constants of the simplest dibasic organic acid, oxalic acid were determined conductometrically and pH metrically in ethanol + water mixtures (0–87 wt% of ethanol). These data were coupled with solubility values of oxalic acid and potassium hydrogen oxalate to calculate the Gibbs energies of transfer of oxalic acid, bioxalate(HOXThe p[H

Studies on Thermodynamic Dissociation Constants of 2,2’-Bipyridine, or 1,10-Phenanthroline in Acetone + Water Mixtures and Gibbs Energy of Transfer of the Hydrogen Ion from Water to Acetone + Water Mixtures

The thermodyamic dissociation constants for isoelectric reaction of the type LHAttempts have been made to understand the basicity and structural properties of acetone + water mixtures from a comparative study of ΔG

Dissociation Constants of p-Nitroaniline in Mixed Solvents and a Critical Assessment of the Solvent-Sorting Equilibrium Method for the Determination of the Single Ion Gibbs Energy of Transfer of H+ Ion from Aqueous to Aquo Rich Organic Solvents

The dissociation constants of p-nitroaniline (B) (A critical assessment of the solvent-sorting equilibrium method using p-nitroaniline as indicator has been made. The method is not suitable to determine the Gibbs energy of transfer of H