breast tumor kinase
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scholarly journals Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Sayem Miah ◽  
Edward Bagu ◽  
Raghuveera Goel ◽  
Yetunde Ogunbolude ◽  
Chenlu Dai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Breast Tumor ◽  
Breast Cancer Cells ◽  
Receptor Signaling ◽  
Estrogen Receptor Signaling ◽  
Breast Tumor Kinase

scholarly journals BRK”ing” Down All We Know About PTK6 in Breast Cancer

2018 ◽  
Author(s):  
Yi Yuan ◽  
Hui Li Ang ◽  
Xianning Lai ◽  
Lingzhi Wang ◽  
Vijay Pandey ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Tumor ◽  
Physiological Role ◽  
Normal Mammary Gland ◽  
Breast Cancers ◽  
Breast Carcinomas ◽  
Therapeutic Approaches ◽  
Chemical Inhibitors ◽  
Breast Tumor Kinase

The search for improved therapeutic approaches to breast cancer are still on going. Breast tumor kinase (BRK, also known as PTK6) is one of the targets, it is highly expressed in breast carcinomas while displaying low or no expression in the normal mammary gland, which hints at the oncogenic role of this enzyme in breast cancer. In these twenty years, an increasing number of studies have focused on understanding the cellular roles of BRK in breast cancers. This review outlines the advances made towards understanding the cellular and physiological role of BRK, the molecular and chemical inhibitors and its therapeutic significance in breast cancer.

scholarly journals Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer

2016 ◽  
Vol 76 (6) ◽  
pp. 1653-1663 ◽  
Author(s):  
Tarah M. Regan Anderson ◽  
Shi Hong Ma ◽  
Ganesh V. Raj ◽  
John A. Cidlowski ◽  
Taylor M. Helle ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Glucocorticoid Receptor ◽  
Triple Negative Breast Cancer ◽  
Breast Tumor ◽  
Triple Negative ◽  
Stress Signaling ◽  
Breast Tumor Kinase

Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia

2015 ◽  
Vol 63 (2) ◽  
pp. 399-407 ◽  
Author(s):  
Yoshiaki Mizuguchi ◽  
Susan Specht ◽  
Kumiko Isse ◽  
Eizaburo Sasatomi ◽  
John G. Lunz ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Breast Tumor ◽  
Protein Tyrosine Kinase ◽  
Protein Tyrosine ◽  
Breast Tumor Kinase
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