Developments in Quality of Work-Life Research and Directions for Future Research

Objective of this paper was to observe trends and developments in quality of work-life research throughout the decades. Previous researchers mostly focused on systematic and general literature reviews. In this paper bibliometric analysis and systematic literature review were combined to observe the trends and developments in quality of work-life research. An electronic Scopus database search initially produced of 867 documents on quality of work-life. Further purposive screening reduced the documents to 752 altogether. Furthermore, a detailed literature review of top 10 most cited publications throughout the decades of quality of work-life research was conducted, to explore construct development, antecedents, and outcomes of quality of work-life. Bibliometric analysis revealed that most of the research was produced from United States, and in areas of business, management, and accounting. Literature review revealed that from 1970s to 1980s, the focus of quality of work-life research was mainly on construct development. From 1990s onward, researchers mostly focused on identifying antecedents and outcomes of quality of work-life at organizational and employee level. Findings of this research suggests various employee and organizational level factors which have been neglected by most influential studies of quality of work-life throughout the decades. Future researchers should focus on these factors to motivate government and organizations to incorporate these factors in their system, and to support the quality of work-life research.

A Tale of Two Perspectives: How Psychology and Neuroscience Contribute to Understanding Personhood

Empirical science, such as psychology and neuroscience, employ diverse methods to develop data driven models and explanations for complex phenomena. In research on the self, differences in these methods produce different depictions of persons. Research in developmental psychology highlights the role of intuitive beliefs, such as psychological essentialism and intuitive dualism, in individuals’ singular, cohesive, and stable sense of self. On the other hand, research in neuroscience highlights the de-centralized, distributed, multitudes of neural networks in competition making selves, with arguments around whether the interpretation of these data imply that the self is somehow fundamental and special to human functioning. In this paper, I explore these discrepant pictures of the self to advance understanding about personhood. Specifically, I suggest that these divergent pictures of self from psychology and neuroscience have the potential to inform philosophical and theological discussions around personhood by anchoring models of persons in empirical views of persons. Likewise, I explore the opportunity for philosophy and theology to inform and enhance scientific research on the self by critiquing scientific bias and construct development as well as highlighting potential limits in understanding selves with empirical models.

Measurement Invariance of Liberal and Authoritarian Notions of Democracy: Evidence From the World Values Survey and Additional Methodological Considerations

This article offers a gentle introduction to the measurement invariance (MI) literature with a focus on its relevance to comparative political research. It reviews 1) the conceptual foundations of MI; 2) standard procedures of testing for MI in practical applications within the multiple-group confirmatory factor analysis (MGCFA) paradigm; and 3) two novel approaches to MI, Bayesian approximate measurement invariance, and MGCFA alignment optimization, which are especially suitable for dealing with extremely heterogeneous data from large-scale comparative surveys typical for modern political science. It then provides an empirical illustration of the key concepts and methods from the MGCFA-MI literature by applying them to testing for MI of two recently introduced measures of democracy attitudes, so-called liberal and authoritarian notions of democracy, across 60 countries in the sixth round of the World Values Survey. These analyses show that both measures can be considered reliable comparative measures of democratic attitudes, although for different reasons. Finally, this study emphasizes that some survey-based constructs, e.g., authoritarian notions of democracy, do not follow the reflective (correlation-based) logic of construct development. These alternative measures, known as formative measures, do not assume strong correlations between their indicators, for which reason it is inappropriate to test their comparability using the reflective MGCFA approach. Instead, their comparability can be tied to their correlations with theoretically relevant external variables.

A Review of Recent Advances in 3D Bioprinting With an Eye on Future Regenerative Therapies in Veterinary Medicine

3D bioprinting is a rapidly evolving industry that has been utilized for a variety of biomedical applications. It differs from traditional 3D printing in that it utilizes bioinks comprised of cells and other biomaterials to allow for the generation of complex functional tissues. Bioprinting involves computational modeling, bioink preparation, bioink deposition, and subsequent maturation of printed products; it is an intricate process where bioink composition, bioprinting approach, and bioprinter type must be considered during construct development. This technology has already found success in human studies, where a variety of functional tissues have been generated for both in vitro and in vivo applications. Although the main driving force behind innovation in 3D bioprinting has been utility in human medicine, recent efforts investigating its veterinary application have begun to emerge. To date, 3D bioprinting has been utilized to create bone, cardiovascular, cartilage, corneal and neural constructs in animal species. Furthermore, the use of animal-derived cells and various animal models in human research have provided additional information regarding its capacity for veterinary translation. While these studies have produced some promising results, technological limitations as well as ethical and regulatory challenges have impeded clinical acceptance. This article reviews the current understanding of 3D bioprinting technology and its recent advancements with a focus on recent successes and future translation in veterinary medicine.

A bioreactor for controlled electromechanical stimulation of developing scaffold-free constructs

ABSTRACTBioreactors are commonly used to apply biophysically-relevant stimulations to tissue-engineered constructs in order to explore how these stimuli influence tissue development, healing, and homeostasis. These bioreactors offer great flexibility as key features of the stimuli (e.g., duty cycle, frequency, amplitude, duration) can be controlled to elicit a desired cellular response. Controlled delivery of mechanical and/or electrical stimulation has been shown to improve the structure and function of engineered tissue constructs, compared to unstimulated controls, for applications in various musculoskeletal soft tissues. However, most bioreactors that apply mechanical and electrical stimulations, do so to a scaffold after the construct has developed, preventing study of the influence these stimuli have on early construct development. Thus, there is a need for a bioreactor that allows the direct application of mechanical and electrical stimulation to constructs as they develop, to enable such exploration and to better mimic key aspects of tissue development. Hence, the objective of this study was to develop and calibrate a bioreactor to deliver precise mechanical and electrical stimulation, either independently or in combination, to developing scaffold-free tissue constructs. Standard Flexcell Tissue Train plates were modified with stainless steel loading pins and stimulating electrodes to integrate direct mechanical and electrical stimulation, respectively, into our established scaffold-free, single-fiber engineering platform. Linear calibration curves were established, then used to apply precise dynamic mechanical and electrical stimulations, over a range of physiologically relevant strains (0.50, 0.70, 0.75, 1.0, 1.5%) and voltages (1.5, 3.5 V), respectively. Once calibrated, applied mechanical and electrical stimulations were not statistically different from their desired target values, and were consistent whether delivered independently or in combination. Indeed, concurrent delivery of mechanical and electrical stimulation resulted in a negligible change in mechanical (< 2%) and electrical (<1%) values, from their independently-delivered values. With this calibrated bioreactor, we can apply precise, controlled, reproducible mechanical and electrical stimulations, alone or in combination, to scaffold-free, tissue engineered constructs as they develop, to explore how these stimuli can be leveraged to advance and accelerate functional tissue engineering in a variety of musculoskeletal soft tissues.IMPACT STATEMENTAs the importance of biophysical stimulation in tissue engineering continues to be recognized and incorporated, this bioreactor provides a platform to further our understanding of the roles independent or combined mechanical and electrical stimulation have in tissue development and functional maturation, and may inform future tissue engineering approaches for clinical applications.