A Synergetic R-Shiny Portal for Modeling and Tracking of COVID-19 Data

The purpose of this paper is to introduce a useful online interactive dashboard (https://mahdisalehi.shinyapps.io/Covid19Dashboard/) that visualize and follow confirmed cases of COVID-19 in real-time. The dashboard was made publicly available on 6 April 2020 to illustrate the counts of confirmed cases, deaths, and recoveries of COVID-19 at the level of country or continent. This dashboard is intended as a user-friendly dashboard for researchers as well as the general public to track the COVID-19 pandemic, and is generated from trusted data sources and built in open-source R software (Shiny in particular); ensuring a high sense of transparency and reproducibility. The R Shiny framework serves as a platform for visualization and analysis of the data, as well as an advance to capitalize on existing data curation to support and enable open science. Coded analysis here includes logistic and Gompertz growth models, as two mathematical tools for predicting the future of the COVID-19 pandemic, as well as the Moran's index metric, which gives a spatial perspective via heat maps that may assist in the identification of latent responses and behavioral patterns. This analysis provides real-time statistical application aiming to make sense to academic- and public consumers of the large amount of data that is being accumulated due to the COVID-19 pandemic.

RACE, ETHICS AND PUBLIC POLICY

There is reform and there is revolution. The fragility of Black lives in white spaces is long overdue for both reformation and revolution within the criminal justice organizational model. It is with particular urgency that current litigation within the Department of Justice be examined as it is an example of latent responses of American government to societal fracture and potential policy reform. There is no more representation of the fragility of Black lives in white spaces than American prison systems and relative to this; sentencing policies that disproportionally affect Blacks. This paper is drawn from deontological ethics, holding that human rights are a moral obligation that should not be excluded in the formation of public policy or the application of justice. It is a further suggestion that within reforms are potentials for revolutions. Salient questions proposed by this research are there accommodation for healing within structurally racist systems. Is reform enough or is there cause for revolutionary actions? The Department of Justice has launched an investigation into an alarming string of deaths within the Mississippi Department of Corrections. This paper will examine potential public policy changes that may emerge from that investigation as well as societal responses. Additionally, this paper is drawn from deontological ethics, holding that human rights are a moral obligation that should not be excluded in the formation of public policy or the application of justice.

Chromatin dynamics underlying latent responses to xenobiotics

Xenobiotic-induced perturbations of somatic tissue or germline epigenomes may underlie delayed-onset and long-lasting adverse effects.