Influence of the nature of the alkanethiol terminal group on the electrochemical stability and blocking ability of self-assembled nanofilms on Au electrode

We studied the effect of the nature of the terminal group of thiols with the same chain length HS (CH2)8 – R (R: -CH3, -CH2OH, -NH2) on the electrodesorption behaviour of well-formed SAMs (the self-assembled monolayers), their stability and blocking ability using voltammetry and chronoamperometry. The nature of the terminal functional group determines the surface properties of SAM and provides the basis for subsequent interactions (for example, with peptides, proteins, DNA) in order to create sensors and bioagents. For the studied thiols, the hydrophilicity of the end groups increases in the series -CH3<< -NH2 ≤ -CH2OH; they also differ in polarity and the possibility of protonation of the amino group. For thiols with -CH3 and -CH2OH groups, an increase in the hydrophilicity of the terminal group leads to the formation of less stable and less ordered films. The replacement of carbon by nitrogen with approximately the same hydrophilicity of the groups (-CH2OH and -NH2) leads to the formation of a more stable film consisting of molecules in the same energy state, butwith poorer insulatingproperties.

Ethanol vs. water: influence of the terminal functional group of the alkyl chain and environment of the self-assembly process on electron transport through the thiol layer

The organization of the thiol chains on the surface strongly depends on the intermolecular interactions between the terminal groups in the chain and the solution environment.

Effects of terminal group and chain length on temperature-responsive chromatography utilizing poly(N-isopropylacrylamide) synthesized via RAFT polymerization

Even using the same homo poly(N-isopropylacrylamide) immobilized silica beads as stationary phases, terminal functional group and chain length significantly affected temperature-dependent elution behavior of steroids.

Cyanide free contraction of disclosed 1,4-dioxane ring as a route to cobalt bis(dicarbollide) derivatives with short spacer between the boron cage and terminal functional group

The 1,4-dioxane derivative of cobalt bis(dicarbollide) reacts with dialkylsulfides and triphenylphosphine to give the corresponding sulfonium and phosphonium derivatives.