A case of peripancreatic plexiform schwannoma

Background Plexiform schwannoma is one of the least common variants of schwannoma, accounting for only 5% of all schwannoma cases. It generally occurs in the skin and subcutaneous tissues and is uncommon in deep soft tissue or viscera. We present an extremely rare case of plexiform schwannoma arising from the peripancreatic plexus. Case presentation A 29-year-old man presented with hyperglycemia detected during a medical checkup. He was diagnosed with type 1 diabetes based on the clinical findings and laboratory tests. During the diagnostic process for diabetes, a 2.5 cm mass was incidentally detected in the pancreas by abdominal ultrasound. Contrast-enhanced computed tomography revealed a mass that was gradually enhanced at the body and tail of the pancreas. Magnetic resonance imaging revealed low signal intensity of the mass on T1-weighted images and high signal intensity on T2-weighted and diffusion-weighted images. Magnetic resonance cholangiopancreatography showed no abnormal findings in the main pancreatic duct. Endoscopic ultrasonography (EUS) showed a lobulated, low-echoic mass with a clear boundary. EUS-guided fine needle biopsy was performed, and spindle-shaped cells that were diffusely immunopositive for S-100 and negative for c-kit and desmin were detected, resulting in a diagnosis of a neurogenic tumor arising from the pancreas or the peripancreatic nerve plexus. The patient underwent laparoscopic spleen-preserving distal pancreatectomy. Although the tumor was connected to the splenic plexus, the splenic artery could be divided along its adventitial plane. Macroscopic findings of the excised tumor consisted of multiple yellowish-white nodules, and its histopathological features were consistent with plexiform schwannoma. There was no pancreatic tissue on the dorsal surface of the tumor, which suggested that the tumor arose from the peripancreatic nerve plexus. Conclusions The findings documented herein can aid in the differential diagnosis of peripancreatic schwannoma and in planning appropriate treatment.

A rare case of plexiform schwannoma on the foot

Plexiform schwannoma mainly presented as an asymptomatic nodule located on the head, neck, or upper extremities. The presentation of this tumor on the dorsum of the foot is very rare. Herein, we report a rare case of pretty large plexiform schwannoma on the toe of a male patient.

Plexiform Schwannoma Masquerading as Giant Cell Tumor of Tendon Sheath- A Case Report

Plexiform schwannoma is a rare benign variant of Schwann cell tumor characterised by multinodular plexiform growth pattern. Usual location of this tumor includes trunk, head, neck and upper extremities but it may rarely be found in lower extremities. It generally affects young adults with no sex predilection. We report a case of 37 years old male who presented with gradually progressive swelling of right little finger of 28years duration that was diagnosed as giant cell tumor of tendon sheath clinically, radiologically and intraoperatively. Authors wish to discuss the case due to its clinical rarity and diagnostic difficulties due to many common histological mimickers at that site.