Welfare Chauvinism, Populist Radical Right Parties and Health Inequalities Comment on "A Scoping Review of Populist Radical Right Parties’ Influence on Welfare Policy and its Implications for Population Health in Europe"

In this short commentary, we examine the implications of the welfare chauvinism of the populist radical right (PRR) for health inequalities by examining the international evidence about the impact of previous periods of welfare state contraction on population health and health inequalities. We argue that parties from various political traditions have in fact long engaged in stigmatisation of welfare recipients to justify welfare state retrenchment, a technique that the PRR have now ‘weaponised.’ We conclude by reflecting on implications of the rise of the PRR for the future of welfare states and health inequalities in the context of coronavirus disease 2019 (COVID-19).

Effect of a myosin regulatory light chain mutation K104E on actin-myosin interactions

Familial hypertrophic cardiomyopathy (FHC) is the most common cause of sudden cardiac death in young individuals. Molecular mechanisms underlying this disorder are largely unknown; this study aims at revealing how disruptions in actin-myosin interactions can play a role in this disorder. Cross-bridge (XB) kinetics and the degree of order were examined in contracting myofibrils from the ex vivo left ventricles of transgenic (Tg) mice expressing FHC regulatory light chain (RLC) mutation K104E. Because the degree of order and the kinetics are best studied when an individual XB makes a significant contribution to the overall signal, the number of observed XBs in an ex vivo ventricle was minimized to ∼20. Autofluorescence and photobleaching were minimized by labeling the myosin lever arm with a relatively long-lived red-emitting dye containing a chromophore system encapsulated in a cyclic macromolecule. Mutated XBs were significantly better ordered during steady-state contraction and during rigor, but the mutation had no effect on the degree of order in relaxed myofibrils. The K104E mutation increased the rate of XB binding to thin filaments and the rate of execution of the power stroke. The stopped-flow experiments revealed a significantly faster observed dissociation rate in Tg-K104E vs. Tg-wild-type (WT) myosin and a smaller second-order ATP-binding rate for the K104E compared with WT myosin. Collectively, our data indicate that the mutation-induced changes in the interaction of myosin with actin during the contraction-relaxation cycle may contribute to altered contractility and the development of FHC.

Secession and the invisible hand of the international system

This article argues that 1945 constitutes an historical inflection point from a period of state expansion to state contraction and that this transformation is primarily the result of changes at the international level. Just as security and economic pressures drove lead states to expand in earlier times, changing conditions in the post-1945 period led to a contraction in state size. The change from multipolarity, the development of the territorial integrity norm, the shift to nuclear deterrence, and the burgeoning global economy contributed to the milieu in which states evaluate the costs and benefits of holding territory, and this has enabled states to permit secession more frequently. The result has been an increase in the rate of peaceful secession and a corresponding proliferation in the number of sovereign states. I test this argument both qualitatively and quantitatively using original data on secessionist movements and internal administrative regions between 1816 and 2005.

Public Attitudes toward Government Spending in the Asia-Pacific Region

This article describes public attitudes toward government spending in Australia, China, India, Japan, Russia, and the United States, the six major economies of the Asia-Pacific region. An analysis of the 2008 AsiaBarometer Survey data shows that ordinary citizens of the sample countries favored increased, rather than reduced, government spending on a wide range of policy programs. It is also found that support for state activism was stronger in former state socialist countries than in market capitalist ones. Although economic interests, symbolic predispositions, and social positions influenced spending preferences to varying degrees, left–right ideology was particularly conspicuous in most countries surveyed. It is evident that the mass publics of the major economies of the Asia-Pacific region did not strongly endorse state contraction or retrenchment, even in the wake of economic globalization and the neoliberal reform movement.