nucleotide binding domain 2 Latest Research Papers

High-affinity Zn(ii) bridging C1344 of nucleotide-binding domain 2 (NBD2) with E402 of NBD1, D173 of intracellular loop1 (ICL1) and the adenine group of ATP at the degenerate site may stimulate channel opening of poorly-phosphorylated human CFTR once the high-affinity Fe(iii) site at the interface of the regulatory (R) domain and ICL3 is removed.

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Involvement of the heterodimeric interface region of the nucleotide binding domain-2 (NBD2) in the CFTR quaternary structure and membrane stability

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/j.bbamcr.2015.06.003 ◽

2015 ◽

Vol 1853 (10) ◽

pp. 2420-2431

Author(s):

Julien Micoud ◽

Sylvain Chauvet ◽

Klaus Ernst Ludwig Scheckenbach ◽

Nadia Alfaidy ◽

Marc Chanson ◽

...

Keyword(s):

Quaternary Structure ◽

Nucleotide Binding ◽

Membrane Stability ◽

Binding Domain ◽

Interface Region ◽

Nucleotide Binding Domain ◽

Nucleotide Binding Domain 2

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Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation

Journal of Biological Chemistry ◽

10.1074/jbc.m113.520759 ◽

2013 ◽

Vol 289 (2) ◽

pp. 848-867 ◽

Cited By ~ 33

Author(s):

Morgan E. DeSantis ◽

Elizabeth A. Sweeny ◽

David Snead ◽

Eunice H. Leung ◽

Michelle S. Go ◽

...

Keyword(s):

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Middle Domain ◽

Distal Loop ◽

Dependent Protein ◽

Nucleotide Binding Domain 2

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Two Neonatal Diabetes Mutations on Transmembrane Helix 15 of SUR1 Increase Affinity for ATP and ADP at Nucleotide Binding Domain 2

Journal of Biological Chemistry ◽

10.1074/jbc.m112.349019 ◽

2012 ◽

Vol 287 (22) ◽

pp. 17985-17995 ◽

Cited By ~ 21

Author(s):

David Ortiz ◽

Peter Voyvodic ◽

Lindsay Gossack ◽

Ulrich Quast ◽

Joseph Bryan

Keyword(s):

Transmembrane Helix ◽

Neonatal Diabetes ◽

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Nucleotide Binding Domain 2

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The nucleotide-binding domain 2 of the human transporter protein MRP6

Journal of Bioenergetics and Biomembranes ◽

10.1007/s10863-011-9372-5 ◽

2011 ◽

Vol 43 (5) ◽

pp. 465-471 ◽

Cited By ~ 13

Author(s):

Angela Ostuni ◽

Rocchina Miglionico ◽

Magnus Monné ◽

Maria Antonietta Castiglione Morelli ◽

Faustino Bisaccia

Keyword(s):

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Transporter Protein ◽

Nucleotide Binding Domain 2

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Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2

Journal of Biological Chemistry ◽

10.1074/jbc.m110.166959 ◽

2010 ◽

Vol 286 (9) ◽

pp. 7202-7213 ◽

Cited By ~ 19

Author(s):

Surtaj H. Iram ◽

Susan P. C. Cole

Keyword(s):

Amino Acids ◽

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Cytoplasmic Loop ◽

And Function ◽

Nucleotide Binding Domain 2

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CFTR missing the last four transmembrane segments and nucleotide binding domain 2 resides in the ER but escapes the cell's quality control mechanism

Journal of Cystic Fibrosis ◽

10.1016/s1569-1993(10)60053-7 ◽

2010 ◽

Vol 9 ◽

pp. S14

Author(s):

L. Cebotaru ◽

W.B. Guggino

Keyword(s):

Quality Control ◽

Control Mechanism ◽

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Transmembrane Segments ◽

Quality Control Mechanism ◽

Nucleotide Binding Domain 2

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Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0707428104 ◽

2007 ◽

Vol 104 (48) ◽

pp. 18988-18992 ◽

Cited By ~ 40

Author(s):

H. de Wet ◽

M. G. Rees ◽

K. Shimomura ◽

J. Aittoniemi ◽

A.-M. Patch ◽

...

Keyword(s):

Atpase Activity ◽

Neonatal Diabetes ◽

Nucleotide Binding ◽

Binding Domain ◽

Nucleotide Binding Domain ◽

Nucleotide Binding Domain 2

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Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport

Biochimica et Biophysica Acta (BBA) - Biomembranes ◽

10.1016/j.bbamem.2006.11.009 ◽

2007 ◽

Vol 1768 (2) ◽

pp. 324-335 ◽

Cited By ~ 6

Author(s):

Runying Yang ◽

Xiu-bao Chang

Keyword(s):

Hydrogen Bond ◽

Multidrug Resistance ◽

Solute Transport ◽

Crucial Role ◽

Bond Formation ◽

Multidrug Resistance Protein ◽

Nucleotide Binding Domain ◽

Hydrogen Bond Formation ◽

Resistance Protein ◽

Nucleotide Binding Domain 2

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Functional Analysis of Genetic Mutations in Nucleotide Binding Domain 2 of the Human Retina Specific ABC Transporter†

Biochemistry ◽

10.1021/bi034481l ◽

2003 ◽

Vol 42 (36) ◽

pp. 10683-10696 ◽

Cited By ~ 8

Author(s):

Esther E. Biswas-Fiss

Keyword(s):

Functional Analysis ◽

Abc Transporter ◽

Nucleotide Binding ◽

Binding Domain ◽

Genetic Mutations ◽

Human Retina ◽

Nucleotide Binding Domain ◽

Nucleotide Binding Domain 2

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nucleotide binding domain 2
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Removal of the Fe(iii) site promotes activation of the human cystic fibrosis transmembrane conductance regulator by high-affinity Zn(ii) binding

Involvement of the heterodimeric interface region of the nucleotide binding domain-2 (NBD2) in the CFTR quaternary structure and membrane stability

Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation

Two Neonatal Diabetes Mutations on Transmembrane Helix 15 of SUR1 Increase Affinity for ATP and ADP at Nucleotide Binding Domain 2

The nucleotide-binding domain 2 of the human transporter protein MRP6

Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2

CFTR missing the last four transmembrane segments and nucleotide binding domain 2 resides in the ER but escapes the cell's quality control mechanism

Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes

Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport

Functional Analysis of Genetic Mutations in Nucleotide Binding Domain 2 of the Human Retina Specific ABC Transporter†

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nucleotide binding domain 2Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Removal of the Fe(iii) site promotes activation of the human cystic fibrosis transmembrane conductance regulator by high-affinity Zn(ii) binding

Involvement of the heterodimeric interface region of the nucleotide binding domain-2 (NBD2) in the CFTR quaternary structure and membrane stability

Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation

Two Neonatal Diabetes Mutations on Transmembrane Helix 15 of SUR1 Increase Affinity for ATP and ADP at Nucleotide Binding Domain 2

The nucleotide-binding domain 2 of the human transporter protein MRP6

Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2

CFTR missing the last four transmembrane segments and nucleotide binding domain 2 resides in the ER but escapes the cell's quality control mechanism

Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes

Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport

Functional Analysis of Genetic Mutations in Nucleotide Binding Domain 2 of the Human Retina Specific ABC Transporter†

nucleotide binding domain 2
Recently Published Documents