Vladyslav Volodymyrovych Povorozniuk

On June 12, 2021, Vladyslav Volodymyrovych Povoroznyuk, the scientific director of the Department of Clinical Physiology and Pathology of the Musculoskeletal System of the State Institution “Institute of Gerontology named after DF Chebotaryov NAMS of Ukraine ", President of the Ukrainian Association of Osteoporosis and the Ukrainian Association of Menopause, Andropause and Musculoskeletal Diseases, President of the Ukrainian Division of EVIDAS, Member of the Board of the International Osteoporosis Association (IOF), Deputy Chairman of the Gerontologist Of Ukraine, Vice President of the Ukrainian Association of Rheumatologists, Member of the Board of the Ukrainian Association of Orthopedists-Traumatologists, Member of the Public Council of the Ukrainian Federation of Public Organizations for Civil Society Health Promotion, Honorary Member of the Association of Implantologists of Ukraine, Member of International Associations ACR, ASB EFORT, EMAS, EULAR, ISCD, ISSAM, OARSI, SICOT, director of the Ukrainian Scientific and Medical Center for Osteoporosis.

Sketches of medical terminology

This article appeared on the several sciences border: clinical anatomy, clinical physiology and philology. Accordingly, its authors are a clinician, a teacher of higher education and a philologist. The authors critically analyze some of the Ukrainian (Greek and Latin derivative) terms based on special literature and writing sources, philology works and their own experience. At the same time, they substantiate every nation’s right to introduce terms into their special scientific nomenclature that are more common in this language, folk household, in accordance with their ideas. The authors call for the correction of some Ukrainian and Latin terms indicating inflammation, as well as - to distinguish adjectives in the clinical and anatomical nomenclature of ones that indicate quality from those indicating the relation, belonging to a particular subject, formation, phenomenon. The terms in the Ukrainian language was often formed under other languages influence and sound sometimes wrong, so it makes sense to replace some medical terms with new, correct ones. It seems like some, firmly rooted terms, require some correction. First of all, as already mentioned, those of them that are based on subject analogies (analog terminology). To develop the Ukrainian language in all spheres of science, including medical science language is our duty. And the work on Ukrainian medical terminology improving is a permanent process, as well as the society development in general.

Clinical physiology aspects of chloremia in fluid therapy: a systematic review

Background This systematic review discusses a clinical physiology aspect of chloride in fluid therapy. Crystalloid solutions are one of the most widely used remedies. While generally used in medicine for almost 190 years, studies focused largely on their safety have only been published since the new millennium. The most widely used solution, normal saline, is most often referred to in this context. Its excessive administration results in hyperchloremic metabolic acidosis with other consequences, including higher mortality rates. Methods Original papers and review articles eligible for developing the present paper were identified by searching online in the electronic MEDLINE database. The keywords searched for included hyperchloremia, hypochloremia, and compound words containing the word “chloride,” infusion therapy, metabolic acidosis, renal failure, and review. Results A total of 21,758 papers published before 31 May 2020 were identified; of this number, 630 duplicates were removed from the list. Upon excluding articles based on their title or abstract, 1850 papers were screened, of which 63 full-text articles were assessed. Conclusions According to the latest medical concepts, dyschloremia (both hyperchloremia and hypochloremia) represents a factor indisputably having a negative effect on selected variables of clinical outcome. As infusion therapy can significantly impact chloride homeostasis of the body, the choice of infusion solutions should always take into account the potentially adverse impact of chloride content on chloremia and organ function.

First person – Samanta Sarti

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Samanta Sarti is first author on ‘Inducible modulation of miR-204 levels in a zebrafish melanoma model’, published in BiO. Samanta conducted the research described in this article while a PhD student in Laura Poliseno's lab at the Oncogenomics Unit Core Research Laboratory (CRL), ISPRO/Institute of Clinical Physiology (IFC), CNR, in Pisa, Italy. She is now a Postdoctoral researcher in the lab of Samuel Sidi in the Department of Medicine, Division of Hematology and Medical Oncology and Department of Cell, Developmental and Regenerative Biology, at the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai in New York, investigating the role of miR-204 in melanoma development by its inducible modulation in a zebrafish melanoma model.