Perspective of molecular immune response of SARS-COV-2 infection

COVID-19 is a type of Pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). When COVID-19 arise in Wuhan China and rapidly spread throughout to the World, we need to learn how pathogenesis and immune responses occur in the bodies in more detail. COVID-19 is the third Severe Respiratory Disease outbreak caused by the Coronavirus in the past two decades after Severe Acute Respiratory Syndrome (SARS) in the 2002 and Middle East Respiratory Syndrome (MERS) in 2012. The Articles from PUBMED and Research Gate were searched for studies on the immune response of COVID-19 infection by SARS-CoV-2. SARS-CoV-2 increases the number of neutrophils, suppresses IFN, increases the activity of Th1/Th17, B cells, CD8+ and CD4+, and causes cytokine storms especially pro-inflammatory cytokines which can increase respiration disorders and multi-organ damage. This review tries to explain about pathogenesis and immune responses of COVID-19 to provide a reference in designing the appropriate immune intervention for treatment and therapeutic such as drug or vaccine based on the recent research progress SARS-CoV-2 and previous studies about SARS CoV and MERS CoV.

Dampak dan Upaya Penggulangan Gangguan Pernapasan Akibat Paparan Debu di PT Bangun Makmur

PT. Bangun Makmur is an industrial company that produces asphalt hotmix. The activities are the solving process of stones, and mixing asphalt and aggregate by using Asphal Mixing Plant (AMP) machine. Dust in the most produce in the process of stone breaking. The purpose of this research is to explain respiration disorders because of dust and afford to cure those disorders. The methods performed are qualitative descriptive with an informer as a worker. Results of this study of respiratory disorders that can occur due to exposure to dust over a long period of time so that it settles in the lungs and causes several diseases and efforts that can be performed is with the provision of counseling to workers about the dangers of dust exposure to allow workers to wear masks when they are in the working environment and to conduct regular employee health checks. Dust-induced illness in the workplace is Influenza and chemical Pneumonitis, which is inflammation of the lungs occurring due to inhaling gases and chemicals.

Dampak dan Upaya Penanggulangan Gangguan Pernafasan Akibat Paparan Debu di PT Bangun Makmur

PT. Bangun Makmur Utama is an industrial company that produces asphalt hotmix. The activities are the solving process of stones, and mixing asphalt and aggregate by using Asphal Mixing Plant (AMP) machine. Dust in the most produce in the process of stone breaking. The purpose of this research is to explain respiration disorders because of dust and afford to cure those disorders. The methods performed are qualitative descriptive with an informer as a worker. Results of this study of respiratory disorders that can occur due to exposure to dust over a long period of time so that it settles in the lungs and causes several diseases and efforts that can be performed is with the provision of counseling to workers about the dangers of dust exposure to allow workers to wear masks when they are in the working environment and to conduct regular employee health checks. Dust-induced illness in the workplace is Influenza and chemical Pneumonitis, which is inflammation of the lungs occurring due to inhaling gases and chemicals

tugas bahasa indo indri

PT. Bangun Makmur is an industrial company that produces asphalt hotmix. The activities are the solving process of stones, and mixing asphalt and aggregate by using Asphal Mixing Plant (AMP) machine. Dust in the most produce in the process of stone breaking. The purpose of this research is to explain respiration disorders because of dust and afford to cure those disorders. The methods performed are qualitative descriptive with an informer as a worker. Results of this study of respiratory disorders that can occur due to exposure to dust over a long period of time so that it settles in the lungs and causes several diseases and efforts that can be performed is with the provision of counseling to workers about the dangers of dust exposure to allow workers to wear masks when they are in the working environment and to conduct regular employee health checks. Dust-induced illness in the workplace is Influenza and chemical Pneumonitis, which is inflammation of the lungs occurring due to inhaling gases and chemicals