Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible

Colorectal cancer (CRC) is a common cause of cancer and cancer-related death. Surgery is the only curative modality. Fluorescence-enhanced visualization of CRC with targeted fluorescent probes that can delineate boundaries and target tumor-specific biomarkers can increase rates of curative resection. Approaches to enhancing visualization of the tumor-to-normal tissue interface are active areas of investigation. Nonspecific dyes are the most-used approach, but tumor-specific targeting agents are progressing in clinical trials. The present narrative review describes the principles of fluorescence targeting of CRC for diagnosis and fluorescence-guided surgery with molecular biomarkers for preclinical or clinical evaluation.

Herbal Medicines as Cancer Treatment

Cancer is a disease caused by abnormal growth of cells in body tissues that turn into cancer cells. Today, treatment for cancer can be done with chemotherapy, radiotherapy, and surgery. Some of the most commonly used chemotherapy drugs are antimetabolites, DNA interactive compounds, antitubulin compounds, hormones, and molecular targeting compounds. Currently, many herbal plants are trusted by the public as anticancer drugs, as shown by several studies and the availability of herbal plants is relatively easier to find by the public. In addition, medicine from plants Herbs can also be used for the prevention and treatment of cancer. This review will discuss about herbal plants that can be used as anticancer. The results of the review show that the use of herbal plants or natural ingredients in cancer therapy has an effect by various mechanisms such as suppressing cell proliferation, induction of apoptosis, slowing metastasis, without reducing the quality of life of cancer patients.

Chemo-Preventive Action of Resveratrol: Suppression of p53—A Molecular Targeting Approach

Extensive experimental, clinical, and epidemiological evidence has explained and proven that products of natural origin are significantly important in preventing and/or ameliorating various disorders, including different types of cancer that researchers are extremely focused on. Among these studies on natural active substances, one can distinguish the emphasis on resveratrol and its properties, especially the potential anticancer role. Resveratrol is a natural product proven for its therapeutic activity, with remarkable anti-inflammatory properties. Various other benefits/actions have also been reported, such as cardioprotective, anti-ageing, antioxidant, etc. and its rapid digestion/absorption as well. This review aims to collect and present the latest published studies on resveratrol and its impact on cancer prevention, molecular signals (especially p53 protein participation), and its therapeutic prospects. The most recent information regarding the healing action of resveratrol is presented and concentrated to create an updated database focused on this topic presented above.

Herbal Medicines as Cancer Treatment

Cancer is a disease caused by abnormal growth of cells in body tissues that turn into cancer cells. Today, treatment for cancer can be done with chemotherapy, radiotherapy, and surgery. Some of the most commonly used chemotherapy drugs are antimetabolites, DNA interactive compounds, antitubulin compounds, hormones, and molecular targeting compounds. Currently, many herbal plants are trusted by the public as anticancer drugs, as shown by several studies and the availability of herbal plants is relatively easier to find by the public. In addition, medicine from plants Herbs can also be used for the prevention and treatment of cancer. This review will discuss about herbal plants that can be used as anticancer. The results of the review show that the use of herbal plants or natural ingredients in cancer therapy has an effect by various mechanisms such as suppressing cell proliferation, induction of apoptosis, slowing metastasis, without reducing the quality of life of cancer patients.