physiologically based pharmacokinetic model Latest Research Papers

Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gut wall metabolism

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.112520 ◽

2022 ◽

Vol 146 ◽

pp. 112520

Author(s):

Seong-Wook Seo ◽

Dong-Gyun Han ◽

Eugene Choi ◽

Taeuk Park ◽

Jong Hyuk Byun ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Scale Up ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Development of physiologically based pharmacokinetic model using artificial intelligence based approaches for pravastatin during pregnancy

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2021.11.1142 ◽

2022 ◽

Vol 226 (1) ◽

pp. S692-S693

Author(s):

Ananth Kumar Kammala ◽

Lauren Richardson ◽

RamKumar Menon

Keyword(s):

Artificial Intelligence ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Assessment of drug–drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.12.021 ◽

2021 ◽

Author(s):

Shuhei Sakai ◽

Shinji Kobuchi ◽

Yukako Ito ◽

Toshiyuki Sakaeda

Keyword(s):

Drug Interaction ◽

Pharmacokinetic Model ◽

Combination Regimen ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

Download Full-text

Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate

Pharmaceutical Research ◽

10.1007/s11095-021-03128-3 ◽

2021 ◽

Author(s):

Chang Ren ◽

Yao Wang ◽

Mei Zhang ◽

Dexuan Kong ◽

Chen Ning ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Pharmacokinetic Properties ◽

Physiologically Based

Download Full-text

Bayesian Refinement of the Permeability-Limited Physiologically Based Pharmacokinetic Model for Perfluorooctanoic Acid in Male Rats

Chemical Research in Toxicology ◽

10.1021/acs.chemrestox.1c00193 ◽

2021 ◽

Author(s):

Weixiao Cheng ◽

Carla A. Ng

Keyword(s):

Pharmacokinetic Model ◽

Perfluorooctanoic Acid ◽

Male Rats ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetic model revealed the distinct bio-transportation and turnover of arsenobetaine and arsenate in marine fish

Aquatic Toxicology ◽

10.1016/j.aquatox.2021.105991 ◽

2021 ◽

pp. 105991

Author(s):

Haiyan Xiong ◽

Qiao-Guo Tan ◽

Jichao Zhang ◽

Wen-Xiong Wang ◽

Xiangzhou Yuan ◽

...

Keyword(s):

Marine Fish ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100423 ◽

2021 ◽

pp. 100423

Author(s):

Kotaro Itohara ◽

Ikuko Yano ◽

Shunsaku Nakagawa ◽

Atsushi Yonezawa ◽

Tomohiro Omura ◽

...

Keyword(s):

Liver Transplant ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Transplant Patients ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Hepatic Impairment Physiologically Based Pharmacokinetic Model Development: Current Challenges

Current Pharmacology Reports ◽

10.1007/s40495-021-00266-5 ◽

2021 ◽

Author(s):

Agnes Nuo Han ◽

Beatrice Rae Han ◽

Tao Zhang ◽

Tycho Heimbach

Keyword(s):

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15084 ◽

2021 ◽

Author(s):

Jeffry Adiwidjaja ◽

Annette S. Gross ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Ethnic Differences ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based ◽

Dosing Regimens

Download Full-text

Pharmacokinetics and safety of rilpivirine in healthy Japanese subjects and exploration of ethnic sensitivity of rilpivirine pharmacokinetics with physiologically based pharmacokinetic model approach

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100422 ◽

2021 ◽

pp. 100422

Author(s):

Kentaro Ohta ◽

Nobuko Matsushima ◽

Hiromi Tanii ◽

Herta Crauwels ◽

Toshiyuki Kudo ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Ethnic Sensitivity ◽

Japanese Subjects ◽

Model Approach

Download Full-text

physiologically based pharmacokinetic model
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gut wall metabolism

Development of physiologically based pharmacokinetic model using artificial intelligence based approaches for pravastatin during pregnancy

Assessment of drug–drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model

Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate

Bayesian Refinement of the Permeability-Limited Physiologically Based Pharmacokinetic Model for Perfluorooctanoic Acid in Male Rats

Physiologically based pharmacokinetic model revealed the distinct bio-transportation and turnover of arsenobetaine and arsenate in marine fish

Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients

Hepatic Impairment Physiologically Based Pharmacokinetic Model Development: Current Challenges

Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

Pharmacokinetics and safety of rilpivirine in healthy Japanese subjects and exploration of ethnic sensitivity of rilpivirine pharmacokinetics with physiologically based pharmacokinetic model approach

Export Citation Format

physiologically based pharmacokinetic modelRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gut wall metabolism

Development of physiologically based pharmacokinetic model using artificial intelligence based approaches for pravastatin during pregnancy

Assessment of drug–drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model

Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate

Bayesian Refinement of the Permeability-Limited Physiologically Based Pharmacokinetic Model for Perfluorooctanoic Acid in Male Rats

Physiologically based pharmacokinetic model revealed the distinct bio-transportation and turnover of arsenobetaine and arsenate in marine fish

Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients

Hepatic Impairment Physiologically Based Pharmacokinetic Model Development: Current Challenges

Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

Pharmacokinetics and safety of rilpivirine in healthy Japanese subjects and exploration of ethnic sensitivity of rilpivirine pharmacokinetics with physiologically based pharmacokinetic model approach

physiologically based pharmacokinetic model
Recently Published Documents