Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15084 ◽

2021 ◽

Author(s):

Jeffry Adiwidjaja ◽

Annette S. Gross ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Ethnic Differences ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based ◽

Dosing Regimens

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Prediction of Lidocaine Tissue Concentrations Following Different Dosing Regimens During Cardiac Arrest Using a Physiologically Based Pharmacokinetic Model (PBPK)

Critical Care Medicine ◽

10.1097/00003246-199501001-00311 ◽

1995 ◽

Vol 23 (Supplement) ◽

pp. A180

Author(s):

Joseph A. Grillo ◽

Jürgen Venitz ◽

Edgar R. Gonzalez ◽

Joseph P. Ornato

Keyword(s):

Cardiac Arrest ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Tissue Concentrations ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Regimens

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Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.117.076851 ◽

2017 ◽

Vol 45 (12) ◽

pp. 1304-1316 ◽

Cited By ~ 13

Author(s):

Heidi J. Einolf ◽

Wen Lin ◽

Christina S. Won ◽

Lai Wang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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Faculty Opinions recommendation of Terbinafine in combination with other antifungal agents for treatment of resistant or refractory mycoses: investigating optimal dosing regimens using a physiologically based pharmacokinetic model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718144448.793485733 ◽

2013 ◽

Author(s):

Neil Ryder

Keyword(s):

Pharmacokinetic Model ◽

Antifungal Agents ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

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Physiologically based pharmacokinetic model predictions of ivosidenib (AG-120) as a victim and perpetrator of drug–drug interactions

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2018.09.238 ◽

2019 ◽

Vol 34 (1) ◽

pp. S70

Author(s):

Chandra Prakash ◽

Yue Chen ◽

Bin Fan ◽

David Dai ◽

Kha Le ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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A Comparison of Physiologically Based Pharmacokinetic Model Predictions and Experimental Data for Inhaled Ethanol in Male and Female B6C3F1Mice, F344 Rats, and Humans

Toxicology and Applied Pharmacology ◽

10.1006/taap.1997.8161 ◽

1997 ◽

Vol 145 (1) ◽

pp. 147-157 ◽

Cited By ~ 40

Author(s):

Gina M. Pastino ◽

Bahman Asgharian ◽

Kay Roberts ◽

Michele A. Medinsky ◽

James A. Bond

Keyword(s):

Experimental Data ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Male And Female ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based ◽

F344 Rats

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Ethnic differences in biological monitoring of several organic solvents II. A simulation study with a physiologically based pharmacokinetic model

International Archives of Occupational and Environmental Health ◽

10.1007/s004200050184 ◽

1997 ◽

Vol 70 (1) ◽

pp. 41-50 ◽

Cited By ~ 7

Author(s):

Jae-Yeon Jang ◽

Pierre O. Droz

Keyword(s):

Biological Monitoring ◽

Organic Solvents ◽

Ethnic Differences ◽

Simulation Study ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Age Dependent

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Human Risk ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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