scholarly journals Persistent Clostridium Difficile Diarrhea, Thinking Beyond Pseudomembranous Colitis: A Case Report

Cureus ◽  
2021 ◽  
Author(s):  
Aeyidh K Alharbi ◽  
Mohammed A Ahmed ◽  
Abdulhadi Tashkandi ◽  
Fahad A Alkhathaami ◽  
Abdulmalik I Alshehri
Keyword(s):  
Case Report ◽  
Clostridium Difficile ◽  
Pseudomembranous Colitis

scholarly journals Managing Antibiotic Associated Diarrhea With Pseudomembranous Colitis: A Case Report

2018 ◽  
Vol 2 (2) ◽  
pp. 35-37
Author(s):  
Kandla Sharma ◽  
Ankit Mangla
Keyword(s):  
Helicobacter Pylori ◽  
Adverse Event ◽  
Case Report ◽  
Clostridium Difficile ◽  
Antibiotic Therapy ◽  
Clostridium Difficile Infection ◽  
Pseudomembranous Colitis ◽  
Faecal Examination ◽  
Antibiotic Associated Diarrhea ◽  
Oral Metronidazole

Antiobiotic associated diarrhea is a usual adverse event during antibiotic therapy. We present the case of a 32-year-old female diagnosed with diarrhea induced by antibiotics. After eradication of Helicobacter pylori by using antibiotics, she presented with hemorrhagic stools. The faecal examination was positive for, Clostridium difficile infection (CDI) although no toxins were detectable. Vancomycin was initiated for the C. difficile infection but the condition worsened due to treatment non-compliance. Finally oral metronidazole was prescribed. Stool abnormality improved and faecal test became negative after metronidazole treatment.

scholarly journals Pneumatosis Coli Associated with Pseudomembranous Colitis in a Patient following Colonic Surgery

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Jennifer Bailey ◽  
Eldon A. Shaffer
Keyword(s):  
Case Report ◽  
Clostridium Difficile ◽  
Antibacterial Agents ◽  
Pseudomembranous Colitis ◽  
False Negative ◽  
Pneumatosis Intestinalis ◽  
Intestinal Wall ◽  
Colonic Surgery ◽  
Pneumatosis Coli ◽  
Unnecessary Testing

Pneumatosis intestinalis is a rare disorder characterized by gas-filled cysts within the subserosal and/or submucosal regions of the intestinal wall. The source of this gas and its translocation across the mucosa is incompletely understood. Most (85%) cases are associated with medical conditions, ranging from psychiatric through respiratory disorders to gastrointestinal-related diseases; the remaining 15% lack any recognizable cause or association. In this case report, pneumatosis coli (affecting the colon) occurred in a patient following abdominal surgery and was associated with pseudomembranous colitis, which wasClostridium difficiletoxin negative—presumably a false negative. Supportive care and appropriate antibacterial agents sufficed to alleviate symptoms and resolve the pneumatosis. Recognizing this uncommon but important association can avoid high financial and personal costs from unnecessary testing and invasive surgical explorations. Consideration should be given to pseudomembranous colitis as the basis for pneumatosis coli developing in patients who have received antibiotics, once gut ischemia has been ruled out.

scholarly journals Extraintestinal Clostridium difficile infection due to a ribotype different from that isolated from the feces of the patient: A case report

Anaerobe ◽  
2017 ◽  
Vol 47 ◽  
pp. 185-187
Author(s):  
Yoshihiro Onada ◽  
Shiro Endo ◽  
Takahisa Umemoto ◽  
Tomomichi Kajino ◽  
Yoshiharu Amasaki ◽  
...  
Keyword(s):  
Case Report ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection

Recommendations for Surveillance of Clostridium difficile–Associated Disease

2007 ◽  
Vol 28 (2) ◽  
pp. 140-145 ◽  
Author(s):  
L. Clifford McDonald ◽  
Bruno Coignard ◽  
Erik Dubberke ◽  
Xiaoyan Song ◽  
Teresa Horan ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Clostridium Difficile ◽  
Pseudomembranous Colitis ◽  
Ad Hoc ◽  
Toxic Megacolon ◽  
Healthcare Facility ◽  
Case Patient ◽  
Healthcare Settings ◽  
Community Onset ◽  
Laboratory Assay

Background.The epidemiology of Clostridium difficile-associated disease (CDAD) is changing, with evidence of increased incidence and severity. However, the understanding of the magnitude of and reasons for this change is currently hampered by the lack of standardized surveillance methods.Objective and Methods.An ad hoc C. difficile surveillance working group was formed to develop interim surveillance definitions and recommendations based on existing literature and expert opinion that can help to improve CDAD surveillance and prevention efforts.Definitions and Recommendations.A CDAD case patient was defined as a patient with symptoms of diarrhea or toxic megacolon combined with a positive result of a laboratory assay and/or endoscopic or histopathologic evidence of pseudomembranous colitis. Recurrent CDAD was defined as repeated episodes within 8 weeks of each other. Severe CDAD was defined by CDAD-associated admission to an intensive care unit, colectomy, or death within 30 days after onset. Case patients were categorized by the setting in which C. difficile was likely acquired, to account for recent evidence that suggests that healthcare facility-associated CDAD may have its onset in the community up to 4 weeks after discharge. Tracking of healthcare facility–onset, healthcare facility–associated CDAD is the minimum surveillance required for healthcare settings; tracking of community–onset, healthcare facility–associated CDAD should be performed only in conjunction with tracking of healthcare facility–onset, healthcare facility–associated CDAD. Community–associated CDAD was defined by symptom onset more than 12 weeks after the last discharge from a healthcare facility. Rates of both healthcare facility–onset, healthcare facility–associated CDAD and community–onset, healthcare facility–associated CDAD should be expressed as case patients per 10,000 patient–days; rates of community-associated CDAD should be expressed as case patients per 100,000 person-years.

gyn/ob-1. Pregnancy Complicated by Antibiotic-induced Clostridium difficile Pseudomembranous Colitis

2003 ◽  
Vol 96 (Supplement) ◽  
pp. S56
Author(s):  
Wayne Henry Friedman ◽  
Alex Joseph Childs ◽  
Anthony B. Royek
Keyword(s):  
Clostridium Difficile ◽  
Pseudomembranous Colitis
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