scholarly journals Pneumatosis Coli Associated with Pseudomembranous Colitis in a Patient following Colonic Surgery

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Jennifer Bailey ◽  
Eldon A. Shaffer

Pneumatosis intestinalis is a rare disorder characterized by gas-filled cysts within the subserosal and/or submucosal regions of the intestinal wall. The source of this gas and its translocation across the mucosa is incompletely understood. Most (85%) cases are associated with medical conditions, ranging from psychiatric through respiratory disorders to gastrointestinal-related diseases; the remaining 15% lack any recognizable cause or association. In this case report, pneumatosis coli (affecting the colon) occurred in a patient following abdominal surgery and was associated with pseudomembranous colitis, which wasClostridium difficiletoxin negative—presumably a false negative. Supportive care and appropriate antibacterial agents sufficed to alleviate symptoms and resolve the pneumatosis. Recognizing this uncommon but important association can avoid high financial and personal costs from unnecessary testing and invasive surgical explorations. Consideration should be given to pseudomembranous colitis as the basis for pneumatosis coli developing in patients who have received antibiotics, once gut ischemia has been ruled out.

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S834-S835
Author(s):  
Marcelle Meseeha ◽  
Maximos Attia ◽  
Tsujung Yang

2018 ◽  
Vol 2 (2) ◽  
pp. 35-37
Author(s):  
Kandla Sharma ◽  
Ankit Mangla

Antiobiotic associated diarrhea is a usual adverse event during antibiotic therapy. We present the case of a 32-year-old female diagnosed with diarrhea induced by antibiotics. After eradication of Helicobacter pylori by using antibiotics, she presented with hemorrhagic stools. The faecal examination was positive for, Clostridium difficile infection (CDI) although no toxins were detectable. Vancomycin was initiated for the C. difficile infection but the condition worsened due to treatment non-compliance. Finally oral metronidazole was prescribed. Stool abnormality improved and faecal test became negative after metronidazole treatment.


2020 ◽  
Vol 40 (2) ◽  
pp. 188
Author(s):  
Rómulo Vargas Rubio ◽  
Janeth Bejarano Rengifo ◽  
Esteban Ardila Silva

Pneumatosis intestinalis (PI) is defined as presence of gas within the intestinal wall. It is a rare condition, usually associated with a wide variety of pathologies. It requires a special diagnostic approach to determine underlying etiology. We present the case of a 18 year old woman with chronic abdominal pain, who presents with peritoneal signs and pneumoperitoneum. Laparoscopy showed NI. Thereafter, Crohn´s disease was diagnosed by balloon enteroscopy.


Cureus ◽  
2021 ◽  
Author(s):  
Aeyidh K Alharbi ◽  
Mohammed A Ahmed ◽  
Abdulhadi Tashkandi ◽  
Fahad A Alkhathaami ◽  
Abdulmalik I Alshehri

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
M. C. Martín-Soberón ◽  
S. Ruiz ◽  
G. De Velasco ◽  
R. Yarza ◽  
A. Carretero ◽  
...  

Abstract Background Pneumatosis intestinalis (PI) is a rare entity which refers to the presence of gas within the wall of the small bowel or colon which is a radiographic sign. The etiology and clinical presentation are variable. Patients with PI may present either with chronic mild non-specific symptoms or with acute abdominal pain with peritonitis. Some cases of intestinal pneumatosis have been reported as adverse events of new oncological treatments such as targeted therapies that are widely used in multiple tumors. Case presentation A 59-year-old caucasian female with radioactive iodine-refractory metastatic thyroid papillary carcinoma with BRAFV600E mutation was treated with dabrafenib and trametinib as a compassionate use. After 4 months treatment, positron emission tomography–computed tomography (PET–CT) showed PI. At the time of diagnosis, the patient was asymptomatic without signs of peritonitis. The initial treatment was conservative and no specific treatment for PI was needed. Unfortunately, after dabrafenib–trametinib withdrawal, the patient developed tumor progression with significant clinical worsening. Conclusions This case report is, in our knowledge, the first description of PI in a patient treated with dabrafenib–trametinib. Conservative treatment is feasible if there are no abdominal symptoms.


Anaerobe ◽  
2017 ◽  
Vol 47 ◽  
pp. 185-187
Author(s):  
Yoshihiro Onada ◽  
Shiro Endo ◽  
Takahisa Umemoto ◽  
Tomomichi Kajino ◽  
Yoshiharu Amasaki ◽  
...  

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