The Global Impact of the COVID-19 Pandemic on Individuals' and Couples' Sexuality

The COVID-19 pandemic and its related restrictions significantly impacted individuals' health, wellbeing, and security. Isolation, limitation of movement, social distancing, and forced cohabiting have had a strong influence on all areas of people's lives as well as on their sexuality. Investigating how the COVID-19 outbreak and its consequences impacted people's sexuality was the primary aim of this review. Particularly, we focused on: (1) the variables associated with the improvement or the deterioration of individuals' and couples' lives during the pandemic; (2) the use of sex as a coping strategy; (3) the impact of COVID-19 outbreak on LGBT people. Results have shown that the worsening of sexual life seems to be related to couples' conflict, emotions and psychological difficulties, being female, being single or away from the partner, being a health care worker, and having children. Moreover, a detrimental effect on sexuality was associated with stress, forced cohabitation, routine, anxiety and worry about the job and the pandemic, feeling partner distance, being unhappy with their partner, and lack of privacy. On the other hand, improvements in sexuality were associated with living happily with a partner, being happy and satisfied with a partner, feeling less stressed and more bored, having more free time, having fewer recreation opportunities, and having minor workload. During the pandemic, there was an increase in using sex toys, pornography consumption, masturbating, and trying sexual experimentations. Among LGBT people, an increase was found in the number of casual sexual partners potentially due to the perceived lower likelihood of transmission through sex. Moreover, the increase in sexual activity may have represented a coping strategy to quarantine-related distress.

Cross reactivity of spike glycoprotein induced antibody against delta and omicron variants before and after third SARS-CoV-2 vaccine dose

Variants of SARS-CoV-2 may evade natural and vaccine induced immunity and monoclonal antibody immunotherapeutics. There is an urgent need to know how well antibodies, induced by healthy and Clinically Extremely Vulnerable (CEV) patients, will bind and thus help reduce transmission and severity of infection from variants of concern (VOC). This study determines the cross-reactive binding of serum antibodies obtained prior to and 28 days after a third vaccination in three cohorts; a health care worker cohort who received three doses of Pfizer-BioNtech (PPP), a cohort of CEV patients received two doses of the AstraZeneca-ChAdOx1-nCoV-19 (AAP) vaccine, followed by a third PFZ vaccine and a haemodialysis cohort that had a mixture of two AZ or PFZ vaccines followed by a PFZ booster. Six months post second vaccine there was evidence of antibody waning with 58.9% of individuals in the HD cohort seropositive against Wuhan, 34.4% Delta and 62.2% Omicron strains. For the AAP cohort, equivalent figures were 62.5%, 45.8% and 91.7% and the PPP cohort 92.2%, 90% and 91.1%. Post third dose vaccination there were universal increases in seropositivity and median optical density. For the HD cohort, 98.8% were seropositive to the Wuhan strain, 97.6% against Delta and 100% against Omicron strains. For the PPP and AAP cohorts, 100% were seropositive against all 3 strains. Lastly, we examined the WHO NIBSC 20/136 standard and there was no loss of antibody binding to either VOC. Similarly, a dilution series of Sotrovimab (GSK) found this therapeutic monoclonal antibody bound similarly to all VOC.

PSYCHOLOGICAL IMPACT OF COVID ON HEALTH CARE WORKER DUE TO COVID 19 PANDEMIC IN A TERTIARY CARE HOSPITAL : A CROSS SECTIONAL STUDY

Background: Corona virus disease 2019 (COVID-19) pandemic caused health crisis. It is important to assess the status of stress, depression and anxiety among medical health care worker (HCWs). Material and Methods: A cross sectional study based on online questionnaire wherein sample size was 160, and HAMD, HAMA and PSS questionnaire was applied and also a self made questionnaire was applied to assess the strategies to cope with covid stress, it consists of 3 items. Data analysed using SPSS software variables compared by using Chi-square/Fishers exact test. Students t-test was used to compare mean values in the two independent groups, and one-way ANOVA was used for more than two groups. The variables with P < 0.05 were considered as statistically significant. Result: A total of 160 sample included, in which 94 (58.1%) were medical staff and 66 (41.25%) were administrative staff. Significant difference was noted in sex(p= 0.004), educational status(p= 0.000), monthly income(p= 0.000), high risk exposure(p= 0.000) and contact with COVID positive suspect or case(p=0.000).There were significant difference noted in depression, anxiety and stress scale as compared to the administrative staff group (p = 0.004, p= 0.004 and p= 0.007) respectively. Conclusions: During this COVID-19 pandemic, HCWs reported a high prevalence of depression, anxiety and stress than the administrative staff.

Study about Tuberculosis in Thailand: An approach to Treatment, GIS and Sichon Model

In this study, we seek to identify geographical areas where ongoing tuberculosis epidemiological characteristics is occurring by linking Geographic Information Systems (GIS) technology in Thailand. In addition, we seek to assess how the directly observed treatment short-course (DOTS) program improved new tuberculosis diagnosis and treatment successes in Sichon District, Nakhon Si Thammarat province, Thailand from 2014 to 2016. The assessment program included seven indicators, and the results revealed that 73 new cases of tuberculosis were admitted for treatment on average every year, with rates of risk group screening findings of 4.28, 5.23, and 6.04 %, respectively. Patients who come to the hospital for diagnosis make up most of the demographic. However, only a minor proportion of patients are identified through community-based primary screening. In the years 2013-2016, the mortality rate of TB cases is expected to rise by 10.25 %, 4.25 %, and 5.56 %, respectively. The elderly and HIV-positive patients comprise most of the TB mortality population. When completing the DOTS program at a hospital, however, the rate of success has fallen short of the targets. Furthermore, the screening technique excludes the target group. As a result, people suffering tuberculosis are reported to be slower and more susceptible to symptoms. As a result, researchers advise that the DOTS program be supported by enhancing treatment follow-up to improve the effectiveness of TB treatment and collaboration with health care worker (HCW).

Perception of Health Care Worker about Uptake of Influenza Vaccine in COVID-19 Era

Background: Considering the important role of health workers in increasing seasonal influenza vaccination coverage and the similarity of seasonal influenza to COVID -19, it is important to increase vaccination rates to reduce the risk of both diseases. Objective: In this study, we aim to investigate how health workers perceive the importance of influenza vaccination, especially in the era of COVID -19. Results: The study involved 316 health workers from Abha in 2021, most of them were physicians, male and young. Participants agreed that influenza can be a serious illness and that the vaccine is very safe. Most HCWs would have preferred to inform their patients about the vaccine. This result changes if the patient disagrees with the COVID -19 vaccine. Conclusion: Despite the low rate of seasonal influenza vaccination, there is a need to recruit health workers to increase this rate, especially in the Covid 19 era.

Who is Coming to Japan Under The New Status of Residence “Specified Skilled Care Workers”?

The Japanese government created a new status of residence called “Specified Skilled Workers” encompassing 14 job categories that have laborer shortages, including long-term care (LTC) workers on April 1, 2019. A survey of students (N=79) at a language institute in Manila, Philippines was conducted in February, 2020 to explore characteristics of future foreign LTC workers in Japan under this new status of residence and identify factors that may help facilitate worker retention. At the time of data collected, these students were studying both Japanese and LTC practices in order to pass skill evaluation tests to enter Japan. Students were asked their perceptions of long-term care, planned lengths of stay, concerns about staying in Japan, and future career plans. Preliminary analyses revealed that 67 (88%) were single, 74(93.7%) had graduated from universities, and a half of them had a nursing background. Most students (93.7%) showed interest in an extended stay in Japan, with some interested in taking the national certified care worker examination which permits extended work in Japan. The most cited concern about being in Japan was “weather, climate and typhoons” (28.1%), followed by “language proficiency” and “living expenses” (21.9%) respectively. As Japan has limited immigration policies but a large need for LTC workers, it is imperative to understand how to attract and retain foreigners who obtain the Specified Skilled Worker status. This includes addressing both work-related and living-related concerns and needs.

Characteristics, Challenges, and Support of Maryland's Direct Care Workers: Findings From a Statewide Agency Survey

Direct care workers (e.g., personal care aides) are paid health care professionals who provide hands on assistance with daily activities to persons with disabilities in home, community, and institutional settings. Many workers are employed by direct care agencies, but little is known or understood about the organizational attributes of these agencies. We describe results from a mixed mode (postal mail, electronic, and telephone) survey of n=1112 residential care agency administrators in Maryland to assess organizational (e.g., size, supplemental services) and direct care worker (e.g., training) characteristics. Preliminary findings indicate that half of direct care agencies’ revenue comes from Medicaid and roughly 40% of clients are living with dementia. Administrators report challenges managing dementia-related behaviors (70%), communicating with persons living with dementia (63%) and interacting with family caregivers (63%). Findings from this work will inform the development of an organizational level intervention that targets training and support of direct care workers.