Case report on cherubism: non-familial variant

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Shelly Arora ◽  
Aadithya B. Urs ◽  
Jeyaseelan Augustine ◽  
Priya Kumar ◽  
Ashi Singh
Keyword(s):  
Case Report ◽  
English Literature ◽  
Giant Cells ◽  
Familial Case ◽  
Multinucleated Giant Cells ◽  
Current Case ◽  
Radiographic Appearance ◽  
Second Year Of Life ◽  
Second Year

Introduction: Cherubism is a rare, non-neoplastic, self-limiting, fibro-osseous disease, characterized by painless expansion of the maxilla, mandible or both. It usually develops in the first and second year of life. The radiographic appearance presentation is ordinarily bilateral, multilocular appearance in the mandible. To the best of our knowledge, very few cases (less than ten) of non-familial cherubism have been reported in the English literature. Objective: To describe non-familial case of cherubism in a 10-year-old child. Materials and methods: The current case was clinically, radiographically and histopathologically analysed for confirmatory diagnosis. Results: H & E stained section showed vascular and cellular stroma containing numerous multinucleated giant cells. Conclusion: Correlating radiographically and histopathologically the case was finally diagnosed as non-familial variant of cherubism.

scholarly journals A rare coexistence of central giant cell granuloma and parathyroid adenoma: Case report

2021 ◽  
Vol 6 (2) ◽  
pp. 155-158
Author(s):  
Rohini Sebastian ◽  
Meethu Rappai
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Parathyroid Adenoma ◽  
Giant Cell ◽  
Stromal Cells ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Bony Lesion

Central giant cell granuloma is a reparative bony lesion characterised by abundant multinucleated giant cells within a sea of spindle shaped mesenchymal stromal cells. Giant cells are scattered throughout the fibrovascular connective tissue stroma containing hemorrhage. Its coexistence with parathyroid adenoma is very rare. Brown tumour is a close differential in this scenario. Herein we present the case of a central giant cell granuloma of maxilla and parathyroid adenoma diagnosed almost during the same time in a 58 years old male.

scholarly journals Vertical genotype 1 HCV infection treated successfully in the second year of life: A case report

2012 ◽  
Vol 18 (12) ◽  
pp. CS113-CS116
Author(s):  
Małgorzata Pawłowska ◽  
Waldemar Halota ◽  
Ewa Smukalska
Keyword(s):  
Case Report ◽  
Hcv Infection ◽  
Genotype 1 ◽  
Second Year Of Life ◽  
Second Year

scholarly journals Xanthogranulomatous cystitis associated with inflammatory bowel disease

2013 ◽  
Vol 4 (4) ◽  
pp. 91 ◽  
Author(s):  
Doreen E. Chung ◽  
Lesley K. Carr ◽  
Linda Sugar ◽  
Michelle Hladunewich ◽  
Leslie A. Deane
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
English Literature ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Benign Condition ◽  
The Third ◽  
Xanthogranulomatous Inflammation ◽  
Inflammatory Bowel ◽  
Bladder Mass

Xanthogranulomatous inflammation is a benign condition characterizedby the presence of multinucleated giant cells, chronicinflammatory cells and lipid-laden macrophages, known as xanthomacells. Only 22 cases of xanthogranulomatous cystitis (XGC)have been reported in the Japanese and English literature. In thisreport, we describe the twenty-third case of XGC and the third caseassociated with inflammatory bowel disease (IBD). A 50-year-oldwoman with quiescent Crohn’s disease was incidentally foundto have a bladder mass on ultrasound. The lesion was resectedthrough a transurethral approach. Pathology demonstrated XGC.At 3 months post-resection, there was no evidence of recurrenceadjacent to the previous resection scar.

scholarly journals Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Corinthia Fabien-Dupuis ◽  
Brian Cooper ◽  
Jeffrey Upperman ◽  
Shengmei Zhou ◽  
Nick Shillingford
Keyword(s):  
Estrogen Receptor ◽  
Case Report ◽  
Staining Pattern ◽  
English Literature ◽  
Review Of The Literature ◽  
Current Case ◽  
Young Females ◽  
Perineal Region ◽  
Cyst Lining ◽  
Ciliated Cyst

Mullerian-type ciliated cysts are uncommon lesions usually found in the lower extremities and perineal region of young females. They have however been reported in males and in other anatomic sites. The cyst lining is typically positive for estrogen receptor (ER), progesterone receptor (PR), PAX-8, and WT1 immunohistochemical stains. This staining pattern has led to the notion that these cysts are of Müllerian origin. The vast majority of cases are located in the dermis where the preferred nomenclature is cutaneous ciliated cyst (CCC). We report a case of Müllerian-type ciliated cyst in the thigh of a 16-year-old girl. Unlike most of the cases reported in the English literature, this cyst was not centered in the dermis. Only a few other cases of Müllerian-type ciliated cysts with no cutaneous connection have been reported. We propose the term ectopic Müllerian cyst for this rare subset of lesions that are not skin based as is the current case.

Chondroid lipoma associated with osteoclast-like multinucleated giant cells - a case report

Apmis ◽  
2017 ◽  
Vol 125 (5) ◽  
pp. 506-508 ◽  
Author(s):  
Mohammed Alyousef ◽  
Areej Al Nemer
Keyword(s):  
Case Report ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Chondroid Lipoma

Intralymphatic Histiocytosis of the Appendix and Fallopian Tube Associated With Primary Peritoneal High-Grade, Poorly Differentiated Adenocarcinoma of Müllerian Origin

2017 ◽  
Vol 25 (4) ◽  
pp. 357-364
Author(s):  
Tien Anh N. Tran ◽  
Quang Tran ◽  
J. Andrew Carlson
Keyword(s):  
Fallopian Tube ◽  
Giant Cells ◽  
Pathological Process ◽  
High Grade ◽  
Multinucleated Giant Cells ◽  
Current Case ◽  
Poorly Differentiated Adenocarcinoma ◽  
First Case ◽  
Poorly Differentiated ◽  
Intralymphatic Histiocytosis

Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literature. To date, ILH has not been described in an internal visceral organ. We report the case of a 68-year-old woman who underwent an appendectomy during a surgical procedure for a primary peritoneal high-grade, poorly differentiated adenocarcinoma of Müllerian origin. Although no malignancy was identified in the appendix, the appendiceal mucosa and submucosa were expanded by dilated vascular channels harboring aggregates of uniform epithelioid cells. Similar histological changes were also identified in the right fallopian tube. Immunohistochemical studies revealed the lymphatic nature of the vessels and the histiocytic origin of the intravascular cells. Of note was the presence of scattered multinucleated giant cells in the histiocytic population, a histological feature not described hitherto in ILH. To the best of the authors’ knowledge, this is the first case of ILH harboring multinucleated giant cells, involving internal visceral organs, and associated with a malignant tumor of the gynecological system. As such, the current case report expands the clinical and histological spectrum of ILH.

scholarly journals Xanthogranulomatous salpingo-oophoritis: a case report and review of literature

2020 ◽  
Vol 9 (10) ◽  
pp. 4316
Author(s):  
Keval A. Patel ◽  
Kinalee P. Chothani ◽  
Bimal Patel ◽  
Dhaneshwar N. Lanjewar
Keyword(s):  
Case Report ◽  
Rare Disease ◽  
Plasma Cells ◽  
Giant Cells ◽  
Ovarian Tumour ◽  
Multinucleated Giant Cells ◽  
Review Of Literature ◽  
Xanthogranulomatous Inflammation ◽  
Extensive Surgery

Xanthogranulomatous inflammation of ovary is a rare disease that is characterized by presence of large number of lipid laden macrophages with an admixture of neutrophils, lymphocytes, plasma cells and multinucleated giant cells. It is misdiagnosed as ovarian tumour that leads to extensive surgery including hysterectomy. In this report we describe a case of Xanthogranulomatous salpingo-oophoritis along with review of literature.

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