scholarly journals Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Corinthia Fabien-Dupuis ◽  
Brian Cooper ◽  
Jeffrey Upperman ◽  
Shengmei Zhou ◽  
Nick Shillingford
Keyword(s):  
Estrogen Receptor ◽  
Case Report ◽  
Staining Pattern ◽  
English Literature ◽  
Review Of The Literature ◽  
Current Case ◽  
Young Females ◽  
Perineal Region ◽  
Cyst Lining ◽  
Ciliated Cyst

Mullerian-type ciliated cysts are uncommon lesions usually found in the lower extremities and perineal region of young females. They have however been reported in males and in other anatomic sites. The cyst lining is typically positive for estrogen receptor (ER), progesterone receptor (PR), PAX-8, and WT1 immunohistochemical stains. This staining pattern has led to the notion that these cysts are of Müllerian origin. The vast majority of cases are located in the dermis where the preferred nomenclature is cutaneous ciliated cyst (CCC). We report a case of Müllerian-type ciliated cyst in the thigh of a 16-year-old girl. Unlike most of the cases reported in the English literature, this cyst was not centered in the dermis. Only a few other cases of Müllerian-type ciliated cysts with no cutaneous connection have been reported. We propose the term ectopic Müllerian cyst for this rare subset of lesions that are not skin based as is the current case.

scholarly journals Concurrent JAK2-Positive Myeloproliferative Disorder and Chronic Myelogenous Leukemia: A Novel Entity? A Case Report With Review of the Literature

2019 ◽  
Vol 7 ◽  
pp. 232470961983232 ◽  
Author(s):  
Gilbert Bader ◽  
Bernard Dreiling
Keyword(s):  
Case Report ◽  
Chronic Myelogenous Leukemia ◽  
English Literature ◽  
Jak2 V617f ◽  
Patient Characteristics ◽  
Myeloproliferative Disorder ◽  
Myelogenous Leukemia ◽  
Jak2 V617f Mutation ◽  
Review Of The Literature ◽  
Shed Light

JAK2 V617F mutation and BCR-ABL translocation have been considered to be mutually exclusive. However, many cases where both hits coexisted have been reported. We have personally managed a case too. We believe this hybrid entity is underdiagnosed. Thus, we decided to shed light on this “double hit” disease to improve its diagnosis and optimize its treatment. We reviewed the English literature in PubMed since JAK2 discovery. We found 33 cases reported so far. We summarized patient characteristics and analyzed possible interactions between JAK2 and BCR-ABL clones.

Solitary Fibrous Tumor of the Parapharyngeal Space: A Case Report and Review of the Literature

1996 ◽  
Vol 75 (10) ◽  
pp. 681-684 ◽  
Author(s):  
Kunal Gangopadhyay ◽  
Khalid Taibah ◽  
M. Babu Manohar ◽  
Hala Kfoury
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Parapharyngeal Space ◽  
English Literature ◽  
Review Of The Literature ◽  
Solitary Fibrous Tumors ◽  
Rare Location ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms generally associated with serosal surfaces, especially the pleura. Recently, these tumors have been documented in a number of extrapleural sites including the head and neck. So far only two cases of parapharyngeal solitary fibrous tumor have been reported in the English literature. Rare location of an uncommon lesion often gives rise to difficulty in diagnosis or to misdiagnosis. In both the previously reported cases, as well as in our case, the diagnosis of solitary fibrous tumor was not made until the excised tumor was subjected to histopathology and immunohistochemistry.

scholarly journals Brown Tumors: A Case Report and Review of the Literature

2016 ◽  
Vol 6 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Özgür Can ◽  
Başak Boynueğri ◽  
Ali Murat Gökçe ◽  
Ebru Özdemir ◽  
Ferhat Ferhatoğlu ◽  
...  
Keyword(s):  
Case Report ◽  
Secondary Hyperparathyroidism ◽  
English Literature ◽  
Bone Lesions ◽  
Brown Tumor ◽  
Review Of The Literature ◽  
Normal Functions ◽  
Brown Tumors ◽  
Clinically Significant

Brown tumors are focal bone lesions, encountered in patients with uncontrolled hyperparathyroidism. They can be located in any part of the skeleton. Clinically significant lesions in the craniofacial bones are rare. Craniofacial involvement may cause facial disfiguration and compromise social ease of the patient and normal functions, such as chewing, talking, and breathing. In this case report, we present a patient with a brown tumor of the craniofacial bones provoked by secondary hyperparathyroidism and review the last 10 years of craniofacial brown tumors associated with secondary hyperparathyroidism in the English literature.

Coral reef aorta: case report and review of the literature

Vascular ◽  
2013 ◽  
Vol 21 (4) ◽  
pp. 251-259 ◽  
Author(s):  
Aleksandra Policha ◽  
Neil Moudgill ◽  
Joshua Eisenberg ◽  
Atul Rao ◽  
Paul DiMuzio
Keyword(s):  
Case Report ◽  
Coral Reef ◽  
Lower Extremity ◽  
English Literature ◽  
Lower Extremities ◽  
Retroperitoneal Approach ◽  
Review Of The Literature ◽  
Rare Form ◽  
Arterial Insufficiency

Coral reef aorta (CRA) is a rare form of atherosclerosis that affects the paravisceral and pararenal aorta and its branches. Patients typically present with arterial insufficiency of the bowels, kidneys and lower extremities. The current mainstay of treatment is operative, typically involving transaortic endarterectomy. Herein, we describe a 54-year-old woman with incapacitating lower extremity claudication secondary to a paravisceral coral reef atheroma treated successfully with transaortic endarterectomy via a left retroperitoneal approach. In addition, we present a complete review of modern English literature on CRA.

scholarly journals Renal Metastases of a Femur Osteosarcoma: A Case Report and a Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Yousra Akasbi ◽  
Samia Arifi ◽  
Karim Lahlaidi ◽  
Tarik Namad ◽  
Nawfel Mellas ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
English Literature ◽  
Renal Involvement ◽  
Review Of The Literature ◽  
Metastatic Osteosarcoma ◽  
History Of ◽  
Renal Metastases

This paper discusses a rare case of renal metastatic osteosarcoma. A 25-year-old man with a history of metastatic osteosarcoma involving his right kidney was referred to our institution for treatment. He was managed with chemotherapy. An exhaustive review of the English literature pertaining to this disease was performed. To our knowledge, this case represents only the sixteenth. The literature suggests that the incidence of renal involvement in osteosarcoma is significant and that the treatment should be multidisciplinary in such patients.

Duodenal Gangliocytic Paraganglioma With Lymph Node Metastasis: A Case Report and Review of the Literature

2003 ◽  
Vol 127 (3) ◽  
pp. e139-e141 ◽  
Author(s):  
Vanitha Sundararajan ◽  
Toni M. Robinson-Smith ◽  
Andrew M. Lowy
Keyword(s):  
Case Report ◽  
Lymph Nodes ◽  
Metastatic Tumor ◽  
Review Of The Literature ◽  
Epithelioid Cells ◽  
Gangliocytic Paraganglioma ◽  
Regional Lymph Nodes ◽  
Current Case ◽  
Node Metastasis ◽  
Spindle Cells

Abstract A case of duodenal gangliocytic paraganglioma (DGP) in a 67-year-old woman is presented. The DGP arose in the second part of the duodenum. Although most of the reported cases of DGP are considered benign, in the present case, we found regional lymph nodes containing metastatic tumor. Previous reports have documented metastases containing only epithelioid cells. The current case demonstrates metastatic tumor in regional lymph nodes containing all 3 of the DGP components (spindle cells, ganglion-like cells, and epithelioid cells).

scholarly journals Hybrid Desmoplastic/Follicular Ameloblastoma of the Mandible: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Masayasu Iwase ◽  
Airi Fukuoka ◽  
Yoko Tanaka ◽  
Naoyuki Saida ◽  
Eriko Onaka ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Histopathological Examination ◽  
English Literature ◽  
Panoramic Radiograph ◽  
Review Of The Literature ◽  
Postoperative Course ◽  
Radiolucent Lesion ◽  
The Right ◽  
Cortical Perforation

Desmoplastic ameloblastoma (DA) is one of the 6 histopathological subtypes of ameloblastoma. Hybrid lesions in which histopathologically conventional ameloblastoma coexists with areas of DA are rare. A 40-year-old male was referred to our hospital complaining of a swelling in the right premolar region of the mandible. A panoramic radiograph showed an area of radiolucency with a well-defined corticated border, whereas computed tomography revealed a unilocular radiolucent lesion and buccal expansion together with cortical perforation. The lesion was treated via enucleation and curettage of the marginal bone and fenestration. A histopathological examination showed a hybrid ameloblastoma with a pronounced desmoplastic pattern and follicular changes. The patient’s postoperative course has been favorable up to now, and no marked changes have been observed. We presented a case of hybrid ameloblastoma and reviewed the 36 reported cases of hybrid ameloblastoma that have been reported in the English literature.

scholarly journals Sarcomatous Carcinoma of the Orbit: A Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. 180-185
Author(s):  
Ninan Mathew ◽  
Mathen Mathew ◽  
Jon Farrah
Keyword(s):  
Case Report ◽  
Poor Prognosis ◽  
Advanced Disease ◽  
English Literature ◽  
Treatment Options ◽  
Malignant Cells ◽  
Review Of The Literature ◽  
Immunological Markers ◽  
Rare Tumours ◽  
The Right

Sarcomatous carcinomas (SCs) are rare tumours that contain malignant cells with epithelial and mesenchymal characteristics. SC rarely presents in the head and neck, and occurs even less often in the orbit. Only 8 cases of SCs located in the orbit or affecting the globe function have been described in the English literature. Here, we report a case of SC affecting the right orbit. SC is associated with a poor prognosis and advanced disease at presentation. Diagnosis is difficult, as histology often fails to definitively identify SC, necessitating a wide panel of molecular/immunological markers. Treatment options are generally aggressive but risky, and frequently yield poor results. Due to the rarity of SC, there has been little focus on the development of improved treatment options.

Case report on cherubism: non-familial variant

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Shelly Arora ◽  
Aadithya B. Urs ◽  
Jeyaseelan Augustine ◽  
Priya Kumar ◽  
Ashi Singh
Keyword(s):  
Case Report ◽  
English Literature ◽  
Giant Cells ◽  
Familial Case ◽  
Multinucleated Giant Cells ◽  
Current Case ◽  
Radiographic Appearance ◽  
Second Year Of Life ◽  
Second Year

Introduction: Cherubism is a rare, non-neoplastic, self-limiting, fibro-osseous disease, characterized by painless expansion of the maxilla, mandible or both. It usually develops in the first and second year of life. The radiographic appearance presentation is ordinarily bilateral, multilocular appearance in the mandible. To the best of our knowledge, very few cases (less than ten) of non-familial cherubism have been reported in the English literature. Objective: To describe non-familial case of cherubism in a 10-year-old child. Materials and methods: The current case was clinically, radiographically and histopathologically analysed for confirmatory diagnosis. Results: H & E stained section showed vascular and cellular stroma containing numerous multinucleated giant cells. Conclusion: Correlating radiographically and histopathologically the case was finally diagnosed as non-familial variant of cherubism.

scholarly journals PAX5-Negative Classical Hodgkin Lymphoma: A Case Report of a Rare Entity and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Elham Vali Betts ◽  
Denis M. Dwyre ◽  
Huan-You Wang ◽  
Hooman H. Rashidi
Keyword(s):  
Case Report ◽  
Hodgkin Lymphoma ◽  
Germinal Center ◽  
English Literature ◽  
Rare Entity ◽  
Classical Hodgkin Lymphoma ◽  
Review Of The Literature ◽  
Diagnostic Dilemma ◽  
Small Minority ◽  
Cell Neoplasm

Classical Hodgkin lymphoma (CHL) is recognized as a B-cell neoplasm arising from germinal center or postgerminal center B-cells. The hallmark of CHL is the presence of CD30 (+) Hodgkin and Reed-Sternberg (HRS) cells with dim expression of PAX5. Nearly all of the HRS cells are positive for PAX5. However, a small minority of HRS cells may lack PAX5 expression, which can cause a diagnostic dilemma. Herein we describe two cases of PAX5-negative CHL and review of the English literature on this very rare entity. It is crucial to be aware of this phenomenon, which in some cases may lead to misdiagnosis and may ultimately adversely affect patient’s management.

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