scholarly journals A fibrous papule with abundant CD34-immunoreactive ganglion-like multinucleated giant cells: a case report and review of the literature

2015 ◽  
Vol 21 (7) ◽  
Author(s):  
Kurt B Schaberg ◽  
Albert S Chiou ◽  
Kevin C Wang ◽  
Barbara M Egbert
Keyword(s):  
Case Report ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Review Of The Literature

scholarly journals Pleomorphic lobular carcinoma of the breast with osteoclast-like giant cells: a case report and review of the literature

2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Lourdes Peña-Jaimes ◽  
Irene González-García ◽  
María Eugenia Reguero-Callejas ◽  
Ignacio Pinilla-Pagnon ◽  
Belén Pérez-Mies ◽  
...  
Keyword(s):  
Case Report ◽  
Lobular Carcinoma ◽  
Giant Cells ◽  
Review Of The Literature ◽  
Carcinoma Of The Breast ◽  
Pleomorphic Lobular Carcinoma

Aneurysmal Bone Cyst of the Larynx Presenting With Hypoglottic Obstruction

2001 ◽  
Vol 125 (5) ◽  
pp. 673-676
Author(s):  
Duilio Della Libera ◽  
Gillian Redlich ◽  
Lucia Bittesini ◽  
Giovanni Falconieri
Keyword(s):  
Aneurysmal Bone Cyst ◽  
Radical Surgery ◽  
Bone Cyst ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Review Of The Literature ◽  
Osteoid Tissue ◽  
Spindle Cells ◽  
Apparent Relationship

Abstract We report a new case of aneurysmal bone cyst of the larynx occurring in a 22-year-old man. The lesion manifested with progressive breathing discomfort and appeared as a polypoid pedunculated mass attached to the subglottic mucosa. Microscopically, it featured numerous mononuclear and multinucleated giant cells surrounding cavernous spaces filled with blood. Foci of proliferating spindle cells and mature osteoid tissue could be recognized. There was no apparent relationship with the cricoid perichondrium. Clinical follow-up was negative for local recurrence. Based on this report and a review of the literature, we conclude that aneurysmal bone cyst of the larynx is phenotypically comparable to its bone homologue; however, its microscopic recognition may be difficult, especially on small biopsy fragments. Since it can be confused with several lesions, including telangiectatic osteosarcoma, awareness of this rare appearance of aneurysmal bone cyst is important to avoid unnecessary radical surgery.

scholarly journals A rare coexistence of central giant cell granuloma and parathyroid adenoma: Case report

2021 ◽  
Vol 6 (2) ◽  
pp. 155-158
Author(s):  
Rohini Sebastian ◽  
Meethu Rappai
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Parathyroid Adenoma ◽  
Giant Cell ◽  
Stromal Cells ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Bony Lesion

Central giant cell granuloma is a reparative bony lesion characterised by abundant multinucleated giant cells within a sea of spindle shaped mesenchymal stromal cells. Giant cells are scattered throughout the fibrovascular connective tissue stroma containing hemorrhage. Its coexistence with parathyroid adenoma is very rare. Brown tumour is a close differential in this scenario. Herein we present the case of a central giant cell granuloma of maxilla and parathyroid adenoma diagnosed almost during the same time in a 58 years old male.

Chondroid lipoma associated with osteoclast-like multinucleated giant cells - a case report

Apmis ◽  
2017 ◽  
Vol 125 (5) ◽  
pp. 506-508 ◽  
Author(s):  
Mohammed Alyousef ◽  
Areej Al Nemer
Keyword(s):  
Case Report ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Chondroid Lipoma

Case report on cherubism: non-familial variant

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Shelly Arora ◽  
Aadithya B. Urs ◽  
Jeyaseelan Augustine ◽  
Priya Kumar ◽  
Ashi Singh
Keyword(s):  
Case Report ◽  
English Literature ◽  
Giant Cells ◽  
Familial Case ◽  
Multinucleated Giant Cells ◽  
Current Case ◽  
Radiographic Appearance ◽  
Second Year Of Life ◽  
Second Year

Introduction: Cherubism is a rare, non-neoplastic, self-limiting, fibro-osseous disease, characterized by painless expansion of the maxilla, mandible or both. It usually develops in the first and second year of life. The radiographic appearance presentation is ordinarily bilateral, multilocular appearance in the mandible. To the best of our knowledge, very few cases (less than ten) of non-familial cherubism have been reported in the English literature. Objective: To describe non-familial case of cherubism in a 10-year-old child. Materials and methods: The current case was clinically, radiographically and histopathologically analysed for confirmatory diagnosis. Results: H & E stained section showed vascular and cellular stroma containing numerous multinucleated giant cells. Conclusion: Correlating radiographically and histopathologically the case was finally diagnosed as non-familial variant of cherubism.

scholarly journals Pineal germinomas with granulomatous inflammation Report of two cases and review of the literature

1998 ◽  
Vol 5 (1) ◽  
pp. E7 ◽  
Author(s):  
Masaji Murakami ◽  
Jun-ichi Kuratsu ◽  
Masato Kochi ◽  
Naoko Kunitoku ◽  
Akihito Hashiguchi ◽  
...  
Keyword(s):  
B Lymphocytes ◽  
Granulomatous Inflammation ◽  
Immunohistochemical Analysis ◽  
Giant Cells ◽  
The Other ◽  
Glial Fibrillary Acid Protein ◽  
Multinucleated Giant Cells ◽  
Review Of The Literature ◽  
Ki 67 ◽  
Acid Protein

The authors report on two cases of pineal germinomas with granulomatous inflammation (granulomatous germinomas). Macroscopically, both tumors were relatively hard and grayish in color. Histological examination revealed a germinoma with multinucleated giant cells and Schaumann bodies in one case, and a germinoma with the background of acellular fibrillated matrix in the other. On immunohistochemical analysis, the granulomatous germinomas were shown to contain many macrophages, T- and B-lymphocytes, and glial fibrillary acid protein-positive cells infiltrating the specimens, compared to nongranulomatous germinomas. Analysis of Masson's trichrome staining tests showed that large areas of the granulomatous germinomas were occupied by a collagenous component; this was not the case in cases of nongranulomatous germinomas. Analysis of monoclonal anti-human Ki-67 results showed that the granulomatous germinomas had a lower score than nongranulomatous germinomas (p < 0.05, unpaired t-test), indicating that germinomas with granulomatous inflammation may have a better prognosis.

Generalized Multinucleate Cell Angiohistiocytoma

2015 ◽  
Vol 19 (3) ◽  
pp. 323-325 ◽  
Author(s):  
Jennifer A.E. Doane ◽  
Kerri Purdy ◽  
Sylvia Pasternak
Keyword(s):  
Treatment Options ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Review Of The Literature ◽  
Multinucleate Cell ◽  
Multinucleate Cells

Background There are less than 100 cases of multinucleate cell angiohistiocytoma (MCA) currently reported in the literature. It occurs as a localized, asymptomatic, benign proliferation of the skin, characterized histologically by irregular multinucleate cells. Due to its novelty, the etiology of the disease and treatment options are still under investigation. Objective To report a case of confirmed, generalized MCA along with a review of the literature on the histology, immunology, potential etiology, and treatment of MCA. Observations The patient was a 41-year-old female with asymptomatic violaceous plaques found on the extensor arms, legs, and trunk. Histopathology revealed increased dilated vascularity and cellularity (composed of mononuclear histiocytes and a few angulated multinucleated giant cells) in the dermis. Conclusions Overall, MCA is a poorly understood, distinct dermatologic phenomenon. Here we present a case of generalized MCA to further the understanding of this disease presentation.

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