scholarly journals Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration

Theranostics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Chenggui Wang ◽  
Min Wang ◽  
Tianzhen Xu ◽  
Xingxing Zhang ◽  
Cai Lin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Skin Regeneration ◽  
Self Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

scholarly journals Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration: Erratum

Theranostics ◽  
2021 ◽  
Vol 11 (20) ◽  
pp. 10174-10175
Author(s):  
Chenggui Wang ◽  
Min Wang ◽  
Tianzhen Xu ◽  
Xingxing Zhang ◽  
Cai Lin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Skin Regeneration ◽  
Self Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

Integrin-binding pro-survival peptide engineered silk fibroin nanosheets for diabetic wound healing and skin regeneration

2020 ◽  
Vol 398 ◽  
pp. 125617
Author(s):  
Huishang Yang ◽  
Chen Lai ◽  
Chengkai Xuan ◽  
Muyuan Chai ◽  
Xuemin Liu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Silk Fibroin ◽  
Skin Regeneration ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

Improving Chronic Diabetic Wound Healing through an Injectable and Self-Healing Hydrogel with Platelet-Rich Plasma Release

2020 ◽  
Vol 12 (50) ◽  
pp. 55659-55674
Author(s):  
Zhiyong Qian ◽  
Haiping Wang ◽  
Yating Bai ◽  
Yuqing Wang ◽  
Lei Tao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Self Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

scholarly journals Regulation of inflammatory microenvironment using a self-healing hydrogel loaded with BM-MSCs for advanced wound healing in rat diabetic foot ulcers

2020 ◽  
Vol 11 ◽  
pp. 204173142094724
Author(s):  
Haotian Bai ◽  
Noh Kyu-Cheol ◽  
Zhonghan Wang ◽  
Yutao Cui ◽  
He Liu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Wound Healing ◽  
Growth Factors ◽  
Chronic Inflammation ◽  
Diabetic Foot ◽  
Normal Skin ◽  
Self Healing ◽  
Diabetic Wound ◽  
Swelling Properties ◽  
Diabetic Wound Healing

A diabetic foot ulcer (DFUs) is a state of prolonged chronic inflammation, which can result in amputation. Different from normal skin wounds, various commercially available dressings have not sufficiently improved the healing of DFUs. In this study, a novel self-healing hydrogel was prepared by in situ crosslinking of N-carboxyethyl chitosan ( N-chitosan) and adipic acid dihydrazide (ADH) with hyaluronic acid-aldehyde (HA-ALD), to provide a moist and inflammatory relief environment to promote stem cell proliferation or secretion of growth factors, thus accelerating wound healing. The results demonstrated that this injectable and self-healing hydrogel has excellent swelling properties, stability, and mechanical properties. This biocompatible hydrogel stimulated secretion of growth factors from bone marrow mesenchymal stem cells (BM-MSCs) and regulated the inflammatory environment by inhibiting the expression of M1 macrophages and promoting the expression of M2 macrophages, resulting in granulation tissue formation, collagen deposition, nucleated cell proliferation, neovascularization, and enhanced diabetic wound healing. This study showed that N-chitosan/HA-ALD hydrogel could be used as a multifunctional injectable wound dressing to regulate chronic inflammation and provide an optimal environment for BM-MSCs to promote diabetic wound healing.

The diabetic wound healing effect of a two-herb formula and its mechanisms of action

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CBS Lau ◽  
VKM Lau ◽  
CL Liu ◽  
PKK Lai ◽  
JCW Tam ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mechanisms Of Action ◽  
Diabetic Wound ◽  
Healing Effect ◽  
Diabetic Wound Healing ◽  
Wound Healing Effect

Critical Regulation of Angiogenesis by Nrf2 Signaling Is Absent in Diabetic Wound Healing

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 634-P
Author(s):  
PIUL S. RABBANI ◽  
JOSHUA A. DAVID ◽  
DARREN L. SULTAN ◽  
ALVARO P. VILLARREAL-PONCE ◽  
JENNIFER KWONG ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing
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