scholarly journals Foot-and-mouth disease virus isolates: Candidate strains for trivalent vaccine development in Nigeria

2016 ◽  
Vol 10 (4) ◽  
pp. 106-113
Author(s):  
Ularamu G Hussaini ◽  
Ibu O John ◽  
Abenga N Jerry ◽  
Lazarus D David ◽  
Wungak S Yiltawe ◽  
...  
Keyword(s):  
Disease Virus ◽  
Vaccine Development ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Trivalent Vaccine ◽  
Virus Isolates

scholarly journals Enhanced Stability of Inactivated Foot-And-Mouth Disease Virus Vaccine With A Novel Solution Buffer.

2021 ◽  
Author(s):  
Jing Li ◽  
Yanming Wei ◽  
Rong Zhang ◽  
Huiqing Yang ◽  
Xuerong Liu
Keyword(s):  
Disease Virus ◽  
Virus Vaccine ◽  
Vaccine Development ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Size Exclusion ◽  
Basic Solution ◽  
The Novel ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Abstract Objectives: Stability is vital for potency of food-and-mouth disease virus vaccine preparation. However, the assembly of inactivated foot-and-mouth disease virus is poor stable and prone to dissociate into 12s under mild acidic or heating conditions, especially emulsified with oil-adjuvant. Thus, it is crucial to explore a suitable medium and condition to improve the stability and efficiency of inactivated FMDV vaccine. Results: In this study, the basic solution buffer and a serious of potential stabilizers, such as carbohydrate, amino acid, antioxidant, salt and antioxidant were screened for evaluating stable effect on FMDV antigen with aid of high performance size exclusion chromatography (HPSEC). On this basis, orthogonal experiment was performed to optimize and finally confirm the formulation. Anti-aging test were carried out to asses the efficiency of formulation on vaccine stability and the results showed that the vaccine was more stabler either stored at 37℃or 4℃. Moreover, physicochemical monitoring revealed that formulation had no influence on the properties of vaccine. The combined results suggested that the novel solution buffer would lower degradation and prolong shelf life of vaccine. In a word, the novel buffer is beneficial to make FMD vaccine more stable and effective, reducing the dependence on cold delivery and storage. This study also provides insight into the processes of optimization and inactivated vaccine development.

Antigenic analysis of serotype O foot-and-mouth disease virus isolates from the Middle East, 1981 to 1988

Vaccine ◽  
1990 ◽  
Vol 8 (4) ◽  
pp. 390-396 ◽  
Author(s):  
A.R. Samuel ◽  
E.J. Ouldridge ◽  
A.E.M. Arrowsmith ◽  
R.P. Kitching ◽  
N.J. Knowles
Keyword(s):  
Middle East ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Antigenic Analysis ◽  
Serotype O ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Virus Isolates

A serological study of Indian type O foot and mouth disease virus isolates

1983 ◽  
Vol 2 (1) ◽  
pp. 145-151
Author(s):  
V.A. SRINIVASAN ◽  
E.J. OULDRIDGE ◽  
M. HEAD ◽  
M.M. RWEYEMAMU
Keyword(s):  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Serological Study ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Virus Isolates

Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades

2008 ◽  
Vol 136 (1-2) ◽  
pp. 16-29 ◽  
Author(s):  
Jajati K. Mohapatra ◽  
Aniket Sanyal ◽  
Divakar Hemadri ◽  
Chakradhar Tosh ◽  
Subhajit Biswas ◽  
...  
Keyword(s):  
Comparative Genomics ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Serotype Asia 1 ◽  
Virus Isolates
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