Comparative Studies of the Potency of Foot and Mouth Disease Virus Trivalent Vaccine with Different Concentration of the Antigenic Content (146S).

2015 ◽  
Vol 45 (1) ◽  
pp. 33 ◽  
Author(s):  
Heba Hussein ◽  
Samy Khalil ◽  
Mohammed Saad
Keyword(s):  
Disease Virus ◽  
Comparative Studies ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Trivalent Vaccine

scholarly journals Foot-and-mouth disease virus isolates: Candidate strains for trivalent vaccine development in Nigeria

2016 ◽  
Vol 10 (4) ◽  
pp. 106-113
Author(s):  
Ularamu G Hussaini ◽  
Ibu O John ◽  
Abenga N Jerry ◽  
Lazarus D David ◽  
Wungak S Yiltawe ◽  
...  
Keyword(s):  
Disease Virus ◽  
Vaccine Development ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Trivalent Vaccine ◽  
Virus Isolates

High resolution surface structure of foot-and-mouth disease virus

1978 ◽  
Vol 36 (2) ◽  
pp. 376-377
Author(s):  
S. S. Breese ◽  
H. L. Bachrach
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Surface Structure ◽  
Disease Virus ◽  
Potassium Phosphate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Physical Measurements ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.

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