scholarly journals Extracellular Vesicles: A Mechanism to Reverse Metastatic Behaviour as a New Approach to Cancer Therapy

10.5772/64391 ◽  
2016 ◽  
Author(s):  
Monerah Al Soraj ◽  
Salma Bargal ◽  
Yunus A. Luqmani
Keyword(s):  
Cancer Therapy ◽  
Extracellular Vesicles ◽  
New Approach

scholarly journals Extracellular vesicles: emerging targets for cancer therapy

2014 ◽  
Vol 20 (7) ◽  
pp. 385-393 ◽  
Author(s):  
Pieter Vader ◽  
Xandra O. Breakefield ◽  
Matthew J.A. Wood
Keyword(s):  
Cancer Therapy ◽  
Extracellular Vesicles

scholarly journals Circulating extracellular vesicles are effective biomarkers for predicting response to cancer therapy

EBioMedicine ◽  
2021 ◽  
Vol 67 ◽  
pp. 103365
Author(s):  
E Zhou ◽  
Yumei Li ◽  
Feng Wu ◽  
Mengfei Guo ◽  
Juanjuan Xu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Extracellular Vesicles

scholarly journals Mesenchymal Stromal Cells Primed with Paclitaxel Provide a New Approach for Cancer Therapy

PLoS ONE ◽  
2011 ◽  
Vol 6 (12) ◽  
pp. e28321 ◽  
Author(s):  
Augusto Pessina ◽  
Arianna Bonomi ◽  
Valentina Coccè ◽  
Gloria Invernici ◽  
Stefania Navone ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
New Approach

scholarly journals Extracellular Vesicles: An Emerging Nanoplatform for Cancer Therapy

2021 ◽  
Vol 10 ◽  
Author(s):  
Yifan Ma ◽  
Shiyan Dong ◽  
Xuefeng Li ◽  
Betty Y. S. Kim ◽  
Zhaogang Yang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Extracellular Vesicles ◽  
Drug Delivery Systems ◽  
Current Knowledge ◽  
Drug Loading ◽  
Cell Communication ◽  
Cancer Therapies ◽  
Therapeutic Function ◽  
Cancer Studies ◽  
Potential Use

Extracellular vesicles (EVs) are cell-derived membrane particles that represent an endogenous mechanism for cell-to-cell communication. Since discovering that EVs have multiple advantages over currently available delivery platforms, such as their ability to overcome natural barriers, intrinsic cell targeting properties, and circulation stability, the potential use of EVs as therapeutic nanoplatforms for cancer studies has attracted considerable interest. To fully elucidate EVs’ therapeutic function for treating cancer, all current knowledge about cellular uptake and trafficking of EVs will be initially reviewed. In order to further improve EVs as anticancer therapeutics, engineering strategies for cancer therapy have been widely explored in the last decade, along with other cancer therapies. However, therapeutic applications of EVs as drug delivery systems have been limited because of immunological concerns, lack of methods to scale EV production, and efficient drug loading. We will review and discuss recent progress and remaining challenges in developing EVs as a delivery nanoplatform for cancer therapy.

Cancer therapy based on extracellular vesicles as drug delivery vehicles

2020 ◽  
Vol 327 ◽  
pp. 296-315 ◽  
Author(s):  
Laura Cabeza ◽  
Gloria Perazzoli ◽  
Mercedes Peña ◽  
Ana Cepero ◽  
Cristina Luque ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Extracellular Vesicles ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles

Lonidamine, a New Approach to Cancer Therapy

Oncology ◽  
1984 ◽  
Vol 41 (1) ◽  
pp. 2-6 ◽  
Author(s):  
A. Caputo ◽  
B. Silvestrini
Keyword(s):  
Cancer Therapy ◽  
New Approach

scholarly journals Redox-Sensitive Nanocomplex for Targeted Delivery of Melittin

Toxins ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 582 ◽  
Author(s):  
Bei Cheng ◽  
Peisheng Xu
Keyword(s):  
Cancer Therapy ◽  
Targeted Delivery ◽  
Cell Permeability ◽  
Peptide Drug ◽  
New Approach ◽  
The Poor ◽  
Poor Stability ◽  
Target Effects

Although peptide therapeutics have been explored for decades, the successful delivery of potent peptides in vitro and in vivo remains challenging due to the poor stability, low cell permeability, and off-target effects. We developed a redox sensitive polymer-based nanocomplex which can efficiently and stably deliver the peptide drug melittin for cancer therapy. The nanocomplex selectively targets cancer cells through lactobionic acid mediated endocytosis and releases melittin intracellularly upon the trigger of elevated redox potential. In vivo study proved that the targeted nanocomplex shows excellent potency in inhibiting tumor growth in a xenograft colon cancer mouse model. Thus, the polymer/melittin nanocomplexes will provide a new approach for melittin based cancer therapy.

An Artificial Lymph Gland: A New Approach to Cancer Therapy

1988 ◽  
Vol 12 (3) ◽  
pp. 243-247 ◽  
Author(s):  
A. A. Pineda ◽  
I. J. Sniecinski ◽  
H. C. Stevenson
Keyword(s):  
Cancer Therapy ◽  
Lymph Gland ◽  
New Approach

Cancer Therapy: A Possible New Approach

Science ◽  
1963 ◽  
Vol 140 (3574) ◽  
pp. 1391-1392 ◽  
Author(s):  
A. Szent-Gyorgyi ◽  
A. Hegyeli ◽  
J. A. McLaughlin
Keyword(s):  
Cancer Therapy ◽  
New Approach

Mesenchymal stem/stromal cell-derived extracellular vesicles as a new approach in stem cell therapy

2016 ◽  
Vol 11 (S1) ◽  
pp. 228-234 ◽  
Author(s):  
V. Börger ◽  
M. Bremer ◽  
A. Görgens ◽  
B. Giebel
Keyword(s):  
Stem Cell ◽  
Cell Therapy ◽  
Extracellular Vesicles ◽  
Stem Cell Therapy ◽  
Stromal Cell ◽  
New Approach
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