scholarly journals The Role of Molecular Imaging Technologies in Breast Cancer Diagnosis and Management

Author(s):  
Anne Rosenberg ◽  
Douglas Arthur ◽  
Mark B. ◽  
Nathalie Johnson ◽  
Leora Lanzkowsky
Pathobiology ◽  
2011 ◽  
Vol 78 (2) ◽  
pp. 99-114 ◽  
Author(s):  
Anthony S.-Y. Leong ◽  
Zhengping Zhuang

In Vivo ◽  
2019 ◽  
Vol 34 (1) ◽  
pp. 355-359
Author(s):  
PIERO FREGATTI ◽  
MARCO GIPPONI ◽  
RAQUEL DIAZ ◽  
RAFFAELE DE ROSA ◽  
FEDERICA MURELLI ◽  
...  

Author(s):  
Hui Li ◽  
Han-Han Li ◽  
Qian Chen ◽  
Yu-Yang Wang ◽  
Chang Chang Fan ◽  
...  

Abnormal cell proliferation caused by abnormal transcription regulation mechanismseems to be one of the reasons for the progression of breast cancer and also thepathological basis. MicroRNA 142 5p (miR 142 5p) is a low expressed miRNA inbreast cancer. T he role of MKL1's regulation of DNMT1 in breast cancer cellproliferation and migration is still unclear. MKL 1 (myocardi n related transcriptionfactor A) can bind to the conserved cis regulatory element CC (A/T) 6GG (called CarGbox) in the promoter to re gulate the transcription of miR 142 5p. The expression ofmiR 142 5p and MKL 1 are positively correlated. In addition, it has been proved thatDNMT1 is the target of miR 142 5p, which inhibits the expression of DNMT1 bytargeting the 3'UTR of DNMT1, thereby forming a feedback loop and inhibiting themigration and proliferation of breast cancer. Our data provide important and novelinsights into the MKL 1/miR 142 5p/DNMT1/maspin signaling pathway, and maybecome a new idea for breast cancer diagnosis, treatment and prognosis.


2008 ◽  
Vol 6 ◽  
pp. S104-S108 ◽  
Author(s):  
Francesca Rovera ◽  
Gianlorenzo Dionigi ◽  
Marina Marelli ◽  
Alberta Ferrari ◽  
Giorgio Limonta ◽  
...  

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