scholarly journals The Changing Role of Pathology in Breast Cancer Diagnosis and Treatment

Pathobiology ◽  
2011 ◽  
Vol 78 (2) ◽  
pp. 99-114 ◽  
Author(s):  
Anthony S.-Y. Leong ◽  
Zhengping Zhuang
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Diagnosis And Treatment ◽  
Changing Role

HER2 targeting as a two-sided strategy for breast cancer diagnosis and treatment: Outlook and recent implications in nanomedical approaches

2010 ◽  
Vol 62 (2) ◽  
pp. 150-165 ◽  
Author(s):  
Miriam Colombo ◽  
Fabio Corsi ◽  
Diego Foschi ◽  
Elisa Mazzantini ◽  
Serena Mazzucchelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Diagnosis And Treatment

Influence of birthplace on breast cancer diagnosis and treatment for Hispanic women

2009 ◽  
Vol 121 (3) ◽  
pp. 743-751 ◽  
Author(s):  
Elena M. Kouri ◽  
Yulei He ◽  
Eric P. Winer ◽  
Nancy L. Keating
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Hispanic Women ◽  
Breast Cancer Diagnosis ◽  
Diagnosis And Treatment

The potential of iodine for improving breast cancer diagnosis and treatment

2013 ◽  
Vol 80 (1) ◽  
pp. 94-98 ◽  
Author(s):  
Michael B. Altman ◽  
Michael J. Flynn ◽  
Robert M. Nishikawa ◽  
Indrin J. Chetty ◽  
Kenneth N. Barton ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Diagnosis And Treatment

scholarly journals Indigenous women's perceptions of breast cancer diagnosis and treatment in Queensland

2000 ◽  
Vol 24 (5) ◽  
pp. 515-519 ◽  
Author(s):  
Celia McMichael ◽  
Maureen Kirk ◽  
Lenore Manderson ◽  
Elizabeth Hoban ◽  
Helen Potts
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Diagnosis And Treatment ◽  
Women’S Perceptions

ACUFOCIN: Randomized clinical trial of ACUpuncture plus standard care versus standard care alone FOr Chemotherapy Induced peripheral Neuropathy (CIPN).

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 12003-12003 ◽  
Author(s):  
Andrew M. Wardley ◽  
David Ryder ◽  
Vivek Misra ◽  
Peter S Hall ◽  
Peter Mackereth ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trial ◽  
Cancer Diagnosis ◽  
Odds Ratio ◽  
Standard Care ◽  
Breast Cancer Diagnosis ◽  
Summary Score ◽  
Mean Difference ◽  
Diagnosis And Treatment ◽  
Grade Ii

12003 Background: CIPN is a dose limiting toxicity, and a major clinical challenge. This study aims to explore the use of acupuncture with standard care (Acu +SC) against SC alone, to reduce symptoms of CIPN. Methods: A phase II, randomised, parallel group design was used to investigate the effectiveness of a 10 week course of acupuncture to manage CIPN. Patients experiencing CIPN ≥ Grade II (CTCAE v4.03), recording a ‘Most Troublesome’ CIPN symptom score of ≥ 3 using the "Measure Yourself Medical Outcome Profile" (MYMOP 2), were randomised (1:1) to either Acu+SC or SC alone. The primary end-point was a ≥ 2 point improvement in MYMOP2 score at week 10 (logistic regression adjusted for stratification factors and baseline MYMOP2 score). The necessary sample size was 100 patients;120 were randomised to allow for attrition (90% power; 10% one-sided alpha), for a hypothesised improvement in success proportions from 30% to 55%. Results: 120 patients were randomised to ACUFOCIN; diagnosis: breast 61 (51%), multiple myeloma 9 (8%), GI 48 (40%), gynaecological 2 (2%). MYMOP2 score for most troubling CIPN symptom at baseline: 3-4 33 (28%), 5-6 87 (73%). CTCAE CIPN at baseline; grade II 103 (86%), grade III 17 (14%). Baseline characteristics were balanced between arms. Primary outcome data were available for 108 participants with 36/54 (67%) successes in the Acu+SC arm compared to 18/55 (33%) in the SC arm. Adjusted success odds ratio was 4.3 (95% CI 1.9-9.6; p < 0.001; Acu+SC vs SC). Additionally, 27/53 (51%) participants achieved a CIPN success (grade ≤ I) in the Acu+SC arm compared to 4/56 (7%) in the SC arm with adjusted odds ratio 13.1 (95% CI 4.1-41.7; p < 0.001; Acu+SC vs SC). Significant reduction in week 10 pain score; mean difference (SC+Acu – SC alone) -1.45 with 95% CI (-2.25, -0.65) after adjustment for week 1 pain, breast cancer diagnosis and treatment complete status. (note pain on a 0-10 scale). Significant increase in the EORTC QLQ-C30 summary score; mean difference (SC+Acu – SC alone) 9.51 with 95% CI (5.01, 14.02) after adjustment for the baseline score, breast cancer diagnosis and treatment complete status. (note summary score on a 0-100 scale). Significant effects seen at week 10 are also present at week 6. The week 6 effect estimates are consistently less than the week 10 effects (but not usually statistically significantly so). Conclusions: In this patient cohort, a 10 week course of acupuncture significantly improved symptoms of CIPN. These results support further investigation within a phase III trial. Clinical trial information: NCT02275403 .

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