CLASSIFICATION OF MAMMOGRAMS HAVING ARCHITECTURAL DISTORTION AND SPICULATED MASSES USING TEXTURE FEATURES

Architectural distortion is the third most common mammographic appearance of nonpalpable breast cancer, representing nearly 6% of abnormalities detected on screening mammography. Although its prevalence on mammography is small compared with calcication or visible mass, architectural distortion is also more difcult to diagnose because it can be subtle and variable in presentation. Early detection of breast cancer is possible by nding architectural distortion in monographic images. Spiculated masses account for about 14% of biopsied lesions and about 81% of these are malignant. Current CAD systems are dramatically better at detecting microcalcications than masses. The sensitivity is considerably lower for Spiculated Masses that are rated as "subtle" by radiologists Moreover, since current systems were devised with masses and calcications in mind, they don’t perform as well on other, less prevalent but still clinically signicant lesion types. In this paper, we propose a computer aided diagnosis system for distinguishing abnormal mammograms with architectural distortion or spiculated masses from normal mammograms. Five types of texture features GLCM, GLRLM, fractal texture, spectral texture and HOG features for the regions of suspicion are extracted. Support vector machine has been used as classier in this work. The proposed system yielded an overall accuracy of 97.29% for mammogram images collected from mini-MIAS database which is better as compared to existing methods.

Preoperative Localization of Recurrence in the Thyroidectomy Bed Using a Radioactive Iodine125 Seed

Intraoperative localization of nonpalpable recurrent thyroid cancer has been reported using needle localization, intraoperative ultrasound (US), dye injection, and radio-guided surgery. We describe the alternative technique of radioactive seed localization (RSL) in 3 patients with residual or recurrent papillary thyroid cancer. This technique has been used for many years in the setting of nonpalpable breast cancer, where it has been shown to be safe and has been associated with greater surgeon satisfaction as well as improved patient tolerability, cosmesis, and outcomes compared to needle localization. In addition, RSL allows complete decoupling of the radiology and surgery schedules. RSL was successful in our 3 patients with regard to safety, patient tolerability, and scheduling.