scholarly journals Toxicity of Nanomaterials and Recent Developments in Lung Disease

Bronchitis ◽  
10.5772/16670 ◽  
2011 ◽  
Author(s):  
R. Asmatulu
Keyword(s):  
Lung Disease ◽  
Recent Developments

scholarly journals NOVOSTI V OBRAVNAVI PLJUČNE BOLEZNI PRI OTROCIH IN MLADOSTNIKIH S CISTIČNO FIBROZO

2015 ◽  
Vol 84 (2) ◽  
Author(s):  
Marina Praprotnik ◽  
Ana Kotnik Pirš ◽  
Barbara Salobir ◽  
Majda Oštir ◽  
Matjaž Turel ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Lung Disease ◽  
Respiratory Insufficiency ◽  
Clinical Skills ◽  
Holistic Approach ◽  
Patient Registries ◽  
Recent Developments ◽  
Chronic Respiratory Insufficiency ◽  
Infection And Inflammation

Cystic fibrosis (CF) is a multi-organ disease,  affecting mostly lungs and gastrointestinal tract. Data from patient registries show that the survival of patients with CF has progressively improved over the past several decades, as a result of advances in antibiotic treatment, supplementation of pancreatic enzymes, better nutrition and a holistic approach to treatment in CF centres.The purpose of this review is to survey recent developments in the treatment of lung disease  in children and adolescents with CF.We describe newborn screening for CF.When chronic respiratory insufficiency occurs, lung transplantation becomes a very important issue.Lung disease is the most common cause of morbidity and mortality in CF patients. Emerging new therapies are targeted at all points in the pathogenesis of lung disease, from drugs that treat infection and inflammation in the airways to gene transfer studies  and to drugs that augment airway surface liquid height. A number of antibacterial agents formulated for inhalation are at various stages of study and there are several anti-inflammatory candidate drugs in  clinical trials.  The most important development  in the recent years is  modulation of the abnormal protein that causes CF, the cystic fibrosis transmembrane regulator (CFTR), where drugs are targeted at specific defects in the transcription, processing or functioning.When chronic respiratory insufficiency occurs, lung transplantation becomes a very important issue. The role of the CF nurse, who has responsibilities in educating and teaching clinical skills to patients and families, is described.

scholarly journals Correction to: Tackling injustices of occupational lung disease acquired in South African mines: recent developments and ongoing challenges

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Barry Kistnasamy ◽  
Annalee Yassi ◽  
Jessica Yu ◽  
Samuel Spiegel ◽  
Andre Fourie ◽  
...  
Keyword(s):  
Lung Disease ◽  
South African ◽  
Occupational Lung Disease ◽  
Recent Developments

scholarly journals Tackling injustices of occupational lung disease acquired in South African mines: recent developments and ongoing challenges

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Barry Kistnasamy ◽  
Annalee Yassi ◽  
Jessica Yu ◽  
Samuel J. Spiegel ◽  
Andre Fourie ◽  
...  
Keyword(s):  
Lung Disease ◽  
South African ◽  
Occupational Lung Disease ◽  
Recent Developments

scholarly journals Recent advances in nontuberculous mycobacterial lung infections

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1710 ◽  
Author(s):  
David Horne ◽  
Shawn Skerrett
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Natural History ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Nontuberculous Mycobacteria ◽  
Mycobacterium Leprae ◽  
Mycobacterium Abscessus ◽  
Recent Developments ◽  
Lung Infections ◽  
Ntm Lung Disease

Nontuberculous mycobacteria (NTM) are members of the Mycobacterium genus other than Mycobacterium tuberculosis complex and Mycobacterium leprae. NTM are widely distributed in the environment and are increasingly recognized as causes of chronic lung disease that can be challenging to treat. In this brief review, we consider recent developments in the ecology, epidemiology, natural history, and treatment of NTM lung disease with a focus on Mycobacterium avium complex (MAC) and Mycobacterium abscessus complex.

Managing Pleural Disease in Acute Medicine (II): Spontaneous Pneumothorax

2008 ◽  
Vol 7 (2) ◽  
pp. 63-69
Author(s):  
Nazir I Lone ◽  
◽  
George Antunes ◽  
Keyword(s):  
Lung Disease ◽  
Spontaneous Pneumothorax ◽  
Thoracic Trauma ◽  
Medical Setting ◽  
Pleural Disease ◽  
Healthy Individuals ◽  
Acute Medicine ◽  
Tube Drainage ◽  
Respiratory Physician ◽  
Recent Developments

Spontaneous pneumothoraces occur in individuals who have not experienced antecedent thoracic trauma. Primary spontaneous pneumothorax occurs in otherwise healthy individuals with no clinically apparent lung disease, whereas secondary pneumothorax is a consequence of an underlying lung disease. This review focuses on their management in the acute medical setting. The specific issues of simple aspiration versus intercostal tube drainage, who can be discharged home safely, and when to refer to a respiratory physician are addressed. In addition, recent developments in the management of pneumothorax are presented.

scholarly journals Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications

2018 ◽  
Vol Volume 13 ◽  
pp. 419-432 ◽  
Author(s):  
Kenneth R Chapman ◽  
Joanna Chorostowska-Wynimko ◽  
A Rembert Koczulla ◽  
Ilaria Ferrarotti ◽  
Noel G McElvaney
Keyword(s):  
Lung Disease ◽  
Clinical Implications ◽  
Antitrypsin Deficiency ◽  
Recent Developments ◽  
Alpha 1 Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin

Trends in Electron Energy Loss Spectroscopy

1977 ◽  
Vol 35 ◽  
pp. 228-229
Author(s):  
C. Colliex ◽  
P. Trebbia
Keyword(s):  
Energy Loss ◽  
Electron Energy ◽  
Electron Energy Loss Spectroscopy ◽  
Materials Science ◽  
Analytical Technique ◽  
Recent Developments ◽  
Quantitative Results ◽  
Electron Microscopes ◽  
Electron Energy Loss ◽  
Primary Electrons

The physical foundations for the use of electron energy loss spectroscopy towards analytical purposes, seem now rather well established and have been extensively discussed through recent publications. In this brief review we intend only to mention most recent developments in this field, which became available to our knowledge. We derive also some lines of discussion to define more clearly the limits of this analytical technique in materials science problems.The spectral information carried in both low ( 0<ΔE<100eV ) and high ( >100eV ) energy regions of the loss spectrum, is capable to provide quantitative results. Spectrometers have therefore been designed to work with all kinds of electron microscopes and to cover large energy ranges for the detection of inelastically scattered electrons (for instance the L-edge of molybdenum at 2500eV has been measured by van Zuylen with primary electrons of 80 kV). It is rather easy to fix a post-specimen magnetic optics on a STEM, but Crewe has recently underlined that great care should be devoted to optimize the collecting power and the energy resolution of the whole system.

Filaments and membranes in the mitotic apparatus

1983 ◽  
Vol 41 ◽  
pp. 544-547
Author(s):  
Kent McDonald
Keyword(s):  
Intermediate Filaments ◽  
Mitotic Spindle ◽  
Mitotic Apparatus ◽  
Light Microscope Level ◽  
Microtubule Associated Proteins ◽  
Recent Developments ◽  
Associated Proteins ◽  
Force Generator ◽  
Spindle Function ◽  
Antibody Technology

At the light microscope level the recent developments and interest in antibody technology have permitted the localization of certain non-microtubule proteins within the mitotic spindle, e.g., calmodulin, actin, intermediate filaments, protein kinases and various microtubule associated proteins. Also, the use of fluorescent probes like chlorotetracycline suggest the presence of membranes in the spindle. Localization of non-microtubule structures in the spindle at the EM level has been less rewarding. Some mitosis researchers, e.g., Rarer, have maintained that actin is involved in mitosis movements though the bulk of evidence argues against this interpretation. Others suggest that a microtrabecular network such as found in chromatophore granule movement might be a possible force generator but there is little evidence for or against this view. At the level of regulation of spindle function, Harris and more recently Hepler have argued for the importance of studying spindle membranes. Hepler also believes that membranes might play a structural or mechanical role in moving chromosomes.

Sign in / Sign up

Export Citation Format

Share Document