Managing Pleural Disease in Acute Medicine (II): Spontaneous Pneumothorax

2008 ◽  
Vol 7 (2) ◽  
pp. 63-69
Author(s):  
Nazir I Lone ◽  
◽  
George Antunes ◽  
Keyword(s):  
Lung Disease ◽  
Spontaneous Pneumothorax ◽  
Thoracic Trauma ◽  
Medical Setting ◽  
Pleural Disease ◽  
Healthy Individuals ◽  
Acute Medicine ◽  
Tube Drainage ◽  
Respiratory Physician ◽  
Recent Developments

Spontaneous pneumothoraces occur in individuals who have not experienced antecedent thoracic trauma. Primary spontaneous pneumothorax occurs in otherwise healthy individuals with no clinically apparent lung disease, whereas secondary pneumothorax is a consequence of an underlying lung disease. This review focuses on their management in the acute medical setting. The specific issues of simple aspiration versus intercostal tube drainage, who can be discharged home safely, and when to refer to a respiratory physician are addressed. In addition, recent developments in the management of pneumothorax are presented.

Managing Pleural Disease in Acute Medicine (I): Pleural Effusion

2007 ◽  
Vol 6 (3) ◽  
pp. 114-120
Author(s):  
Nazir I. Lone ◽  
◽  
George Antunes ◽  
Keyword(s):  
Clinical Practice ◽  
Pleural Effusion ◽  
Pleural Space ◽  
Diagnostic Approach ◽  
Initial Assessment ◽  
Common Finding ◽  
Pleural Disease ◽  
Pleural Effusions ◽  
Acute Medicine ◽  
Recent Developments

A pleural effusion is the accumulation of fluid in the pleural space. It is a relatively common finding in clinical practice. The diagnostic approach to the patient presenting with a pleural effusion is aimed at defining the effusion as a transudate or an exudate. This review summarises the initial assessment and investigation of pleural effusions diagnosed during the acute medical take, and who should be referred for specialist advice. In addition, recent developments, including the measurement of NT-proBNP levels and diagnostic markers for mesothelioma, are presented.

scholarly journals NOVOSTI V OBRAVNAVI PLJUČNE BOLEZNI PRI OTROCIH IN MLADOSTNIKIH S CISTIČNO FIBROZO

2015 ◽  
Vol 84 (2) ◽  
Author(s):  
Marina Praprotnik ◽  
Ana Kotnik Pirš ◽  
Barbara Salobir ◽  
Majda Oštir ◽  
Matjaž Turel ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Lung Disease ◽  
Respiratory Insufficiency ◽  
Clinical Skills ◽  
Holistic Approach ◽  
Patient Registries ◽  
Recent Developments ◽  
Chronic Respiratory Insufficiency ◽  
Infection And Inflammation

Cystic fibrosis (CF) is a multi-organ disease,  affecting mostly lungs and gastrointestinal tract. Data from patient registries show that the survival of patients with CF has progressively improved over the past several decades, as a result of advances in antibiotic treatment, supplementation of pancreatic enzymes, better nutrition and a holistic approach to treatment in CF centres.The purpose of this review is to survey recent developments in the treatment of lung disease  in children and adolescents with CF.We describe newborn screening for CF.When chronic respiratory insufficiency occurs, lung transplantation becomes a very important issue.Lung disease is the most common cause of morbidity and mortality in CF patients. Emerging new therapies are targeted at all points in the pathogenesis of lung disease, from drugs that treat infection and inflammation in the airways to gene transfer studies  and to drugs that augment airway surface liquid height. A number of antibacterial agents formulated for inhalation are at various stages of study and there are several anti-inflammatory candidate drugs in  clinical trials.  The most important development  in the recent years is  modulation of the abnormal protein that causes CF, the cystic fibrosis transmembrane regulator (CFTR), where drugs are targeted at specific defects in the transcription, processing or functioning.When chronic respiratory insufficiency occurs, lung transplantation becomes a very important issue. The role of the CF nurse, who has responsibilities in educating and teaching clinical skills to patients and families, is described.

scholarly journals Value of immune factors for monitoring risk of lung cancer in patients with interstitial lung disease

2019 ◽  
Vol 47 (7) ◽  
pp. 3344-3353
Author(s):  
Ning Li ◽  
Haisheng Hu ◽  
Ge Wu ◽  
Baoqing Sun
Keyword(s):  
Lung Cancer ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Serum Levels ◽  
Scaling Analysis ◽  
Healthy Controls ◽  
Healthy Individuals ◽  
Reactive Protein ◽  
Increased Risk ◽  
Immune Factors

Objective Patients with interstitial lung disease (ILD) are at increased risk of developing lung cancer. We aimed to investigate the clinical significance of serum immune factors in this progression. Methods We retrospectively screened a hospital database from January 2012 to December 2016 for patients with lung cancer and ILD. We measured serum levels of C3, C4, IgA, IgG, IgM, C-reactive protein (CRP), ceruloplasmin (CER), and rheumatoid factor in these patients and in healthy controls. Results We analyzed data for 262 patients with lung cancer, 220 with ILD, and 57 healthy controls. CER levels were significantly higher in patients with lung cancer (0.35 ± 0.10 g/L) compared with both ILD patients (0.31 ± 0.25 g/L) and healthy individuals (0.25 ± 0.04 g/L). C3 and C4 levels were both significantly higher in healthy individuals compared with patients with lung cancer (C3: 1.70 ± 0.29 vs 1.04 ± 0.26 g/L, C4: 0.27 ± 0.24 vs 0.24 ± 0.09 g/L) and ILD (C3: 1.70 ± 0.29 vs 0.97 ± 0.25 g/L, C4: 0.27 ± 0.24 vs 0.21 ± 0.09 g/L). Optimal scaling analysis demonstrated that lung cancer was closely associated with CRP, CER, C3, and C4. Conclusions Increased levels of CRP and CER and decreased levels of C3 and C4 may identify patients with ILD at high risk of developing lung cancer.

scholarly journals Correction to: Tackling injustices of occupational lung disease acquired in South African mines: recent developments and ongoing challenges

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Barry Kistnasamy ◽  
Annalee Yassi ◽  
Jessica Yu ◽  
Samuel Spiegel ◽  
Andre Fourie ◽  
...  
Keyword(s):  
Lung Disease ◽  
South African ◽  
Occupational Lung Disease ◽  
Recent Developments

scholarly journals Tackling injustices of occupational lung disease acquired in South African mines: recent developments and ongoing challenges

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Barry Kistnasamy ◽  
Annalee Yassi ◽  
Jessica Yu ◽  
Samuel J. Spiegel ◽  
Andre Fourie ◽  
...  
Keyword(s):  
Lung Disease ◽  
South African ◽  
Occupational Lung Disease ◽  
Recent Developments
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