scholarly journals Effects of Organic Acids on Growth Performance, Gastrointestinal pH, Intestinal Microbial Populations and Immune Responses of Weaned Pigs

2008 ◽  
Vol 21 (2) ◽  
pp. 252-261 ◽  
Author(s):  
Zheji Li ◽  
Ganfeng Yi ◽  
Jingdong Yin ◽  
Peng Sun ◽  
Defa Li ◽  
...  
Keyword(s):  
Immune Responses ◽  
Organic Acids ◽  
Growth Performance ◽  
Microbial Populations ◽  
Weaned Pigs ◽  
Gastrointestinal Ph

scholarly journals PSXIV-42 Late-Breaking: Effects of yeast cell wall product on growth performance, immune responses, and gene expression of tight junction proteins of weaned pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 333-334
Author(s):  
Hyunjin Kyoung ◽  
Myungwoo Cho ◽  
Hanbae Lee ◽  
Sangwoo Park ◽  
Joowon Kang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Wall ◽  
Immune Responses ◽  
Tight Junction ◽  
Yeast Cell ◽  
Growth Performance ◽  
Experimental Period ◽  
Yeast Cell Wall ◽  
Weaned Pigs ◽  
Tnf Α

Abstract The study was conducted to investigate effects of yeast cell wall product on growth performance, immune responses, and gene expression of tight junction proteins of weaned pigs. A total of 112 weaned pigs (7.98 ± 0.43 kg BW) were randomly assigned to 2 dietary treatments (8 pigs/pen; 7 replicates/treatments) for 4 weeks in a randomized complete block design (block = BW). Dietary treatments were 1) a commercial basal nursery diet (CON) and 2) CON + 0.05% yeast cell wall product (YCW, EasyBio Inc., Seoul, Korea). Blood was collected from one randomly selected pig per pen on d 0, 7, and 14 after weaning. The randomly selected one pig per replicate was euthanized to collect ileum tissue samples at the end of the experimental period. Measurements were growth performance, number of white blood cells (WBC) by an automated hematology analyzer calibrated for porcine blood, cortisol, tumor necrosis factor-α (TNF-α), transforming growth factor-β1, interleukin-1β (IL-1β), and interleukin-6 (IL-6) by the ELISA, and gene expression of tight junction in ileum tissues. Data were analyzed using the PROC GLM procedure of SAS. The statistical model for every measurement included dietary effect and BW as a covariate. Pigs fed YCW had higher (P < 0.10) ADG than those fed CON during overall experimental period. Pigs fed YCW had lower WBC on d 14 (P < 0.10), TNF-α on d 7 (P < 0.10), and decreased IL-1β on d 14 (P < 0.05) than those fed CON. In addition, The YCW increased (P < 0.05) expression of Claudin family, Occludin, Muc1, INF-α, and IL-6, but decreased (P < 0.05) expression of TNF-α genes in the ileum tissues compared with CON. In conclusion, addition of yeast cell wall product in the nursery diet improved growth performance and gut health and modified immune responses of weaned pigs.

scholarly journals Comparison of the Efficacy of Different Organic Acids on Growth Performance and Nutrient Digestibility in Weaned Pigs

2009 ◽  
Vol 51 (1) ◽  
pp. 15-24 ◽  
Author(s):  
Ji-Whan Joo ◽  
YuXin Yang ◽  
Jae-Yong Choi ◽  
Soon-Chon Choi ◽  
Won-Tak Cho ◽  
...  
Keyword(s):  
Organic Acids ◽  
Growth Performance ◽  
Nutrient Digestibility ◽  
Weaned Pigs

scholarly journals Effects of dietary inactivated probiotics on growth performance and immune responses of weaned pigs

2021 ◽  
Author(s):  
Joowon Kang ◽  
Jeong Jae Lee ◽  
Jin Ho Cho ◽  
Jeehwan Choe ◽  
Hyunjin Kyoung ◽  
...  
Keyword(s):  
Immune Responses ◽  
Growth Performance ◽  
Weaned Pigs

scholarly journals PSIV-B-42 Late-Breaking: Effects of dietary inactivated probiotics on growth performance, nutrient digestibility, and immune responses of weaned pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 327-328
Author(s):  
Joowon Kang ◽  
Jong Pyo Chae ◽  
S-H Kim ◽  
J-W Kim ◽  
Sangwoo Park ◽  
...  
Keyword(s):  
Immune Responses ◽  
Growth Performance ◽  
Block Design ◽  
Lactobacillus Rhamnosus ◽  
Experimental Period ◽  
Nutrient Digestibility ◽  
Weaned Pigs ◽  
Biotechnology Research ◽  
Tnf Α ◽  
Dietary Treatments

Abstract The study was conducted to investigate effects of dietary inactivated probiotics on growth performance, nutrient digestibility, and immune responses of weaned pigs. A total of 96 weaned pigs (initial BW = 6.95 ± 0.25 kg) were randomly assigned to 4 dietary treatments with increasing levels of inactive probiotics (4 pigs/replicate; 6 replicates/treatment; 0, 0.1, 0.2, and 0.4%; CON, T1, T2, and T3) in a randomized complete block design (BW and sex as blocks). The inactivated probiotics used in this experiment was a commercial product (CJ CheilJedang Biotechnology Research Institute, Seoul, Korea) containing 1 x 106 CFU/g on stains of Lactobacillus rhamnosus. Pigs were fed respective dietary treatments for 4 weeks. During the last week of the experimental period, pigs were fed their respective dietary treatments containing 0.2% chromic oxide. Fecal samples were collected by rectal palpation daily for the last 3 days after the 4-day adjustment period during the last week of experiment. Blood was collected from randomly selected one pig each pen on d 1, 3, 7, and 14 after weaning. Measurements were growth performance, apparent total tract digestibility (ATTD), TNF-α, TGF-β, CRP, and cortisol by ELISA. Data were analyzed using the MIXED procedure of SAS. The inactivated probiotics increased ADG (471, 501, and 513 vs. 428 g/d; P < 0.05) and G:F (0.65, 0.69, and 0.71 vs. 0.58 g/g; P < 0.05) during overall experimental period compared with CON. The inactivated probiotics increased ATTD of GE (86.87, 87.29, and 88.53 vs. 85.25%; P < 0.05) compared with CON. The inactivated probiotics decreased TNF-α (600, 542, and 523 vs. 849 pg/ml; P < 0.05) and cortisol (5.58, 5.56, and 5.44 vs. 7.25 ng/ml; P < 0.05) on d 7 compared with CON. In conclusion, addition of inactivated probiotics improved growth performance, and nutrient digestibility, and modified immune responses.

scholarly journals Dietary Yeast Cell Wall Improves Growth Performance and Prevents of Diarrhea of Weaned Pigs by Enhancing Gut Health and Anti-Inflammatory Immune Responses

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2269
Author(s):  
Jeong Jae Lee ◽  
Hyunjin Kyoung ◽  
Jin Ho Cho ◽  
Jeehwan Choe ◽  
Younghoon Kim ◽  
...  
Keyword(s):  
Cell Wall ◽  
Body Weight ◽  
Immune Responses ◽  
Yeast Cell ◽  
Growth Performance ◽  
Relative Abundance ◽  
Yeast Cell Wall ◽  
Intestinal Health ◽  
Weaned Pigs ◽  
Tnf Α

Dietary yeast cell wall products (YCW) are recognized as a feed additive due to multifunctional benefits by the biological response modulators. Thus, this study was conducted to verify a potential advantage of YCW for improving growth performance, nutrient digestibility, immune responses, and intestinal health and microbiota of weaned pigs. A total of 112 weaned pigs (7.99 ± 1.10 kg of body weight; 28 days old) were arbitrarily allocated to two experimental treatments with eight pigs (four barrows and four gilts) per pen and seven replicate pens per treatment in a completely randomized block design (block = BW and sex): (1) a basal diet based on corn and soybean meal (CON) and (2) CON + 0.05% YCW. The experimental period was for 4 weeks. There were no differences in final body weight, average daily feed intake, and gain-to-feed ratio between dietary treatments. In contrast, pigs fed YCW had higher average daily gain (p = 0.088) and apparent ileal digestibility of DM (p < 0.05) and energy (p = 0.052) and lower diarrhea frequency (p = 0.083) than those fed control diet (CON). Pigs fed YCW also had a higher (p < 0.05) ratio between villus height and crypt depth, villus width and area, and goblet cell counts in the duodenum and/or jejunum than those fed CON. Dietary YCW decreased (p < 0.05) serum TNF-α and IL–1β of weaned pigs on day 7 and 14, respectively, compared with CON. Furthermore, pigs fed YCW had higher (p < 0.05) ileal gene expression of claudin family, occludin, MUC1, INF-γ, and IL-6 and lower (p < 0.05) that of TNF-α than those fed CON. Lastly, there were no differences in the relative abundance of bacteria at the phylum level between CON and YCW. However, dietary YCW increased (p < 0.05) the relative abundance of genera Prevotella and Roseburia compared with CON. This study provided that dietary YCW improved growth rate, nutritional digestibility, and intestinal health and modified immune responses and intestinal microbiota of weaned pigs.

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