scholarly journals Inter-Rater Agreement in the Clinical Diagnosis of Essential Tremor: Data from the NEDICES-2 Pilot Study

2014 ◽  
Vol 4 (0) ◽  
pp. 04
Author(s):  
Fernando Sierra-Hidalgo ◽  
Juan Pablo Romero ◽  
Felix Bermejo-Pareja ◽  
Alvaro Sánchez-Ferro ◽  
Jesús Hernández-Gallego ◽  
...  
2020 ◽  
pp. 1-1
Author(s):  
Ekaterina Kovalenko ◽  
Aleksandr Talitckii ◽  
Anna Anikina ◽  
Aleksei Shcherbak ◽  
Olga Zimniakova ◽  
...  

2021 ◽  
pp. 10.1212/CPJ.0000000000001145
Author(s):  
Abhishek Lenka ◽  
Sanjay Pandey

ABSTRACTPurpose of the review:To highlight five new things in the research and clinical aspects of essential tremor (ET).Recent findings:The introduction of a new definition of ET and a new category “ET plus” were the major themes of the recent consensus statement. This new change demands a change in the approach to the clinical diagnosis of ET and related diseases. From the pathogenesis standpoint, the cerebellar neurodegenerative model seems to have numerous evidence in its favor compared to the olivary model which has largely fallen out of favor. From the standpoint of therapeutics, magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has enriched the therapeutic armamentarium.Summary:There has been considerable progress in the field of ET. We discuss five new things in this article which include- (i) new definition (ii) ET plus (iii) approach to the diagnosis of ET, (iv) cerebellar degeneration, and (v) MRgFUS thalamotomy.


2014 ◽  
Vol 261 (5) ◽  
pp. 884-888 ◽  
Author(s):  
Isabel Wurster ◽  
Annegret Abaza ◽  
Kathrin Brockmann ◽  
Inga Liepelt-Scarfone ◽  
Daniela Berg

2014 ◽  
Vol 17 (4) ◽  
pp. 717-719 ◽  
Author(s):  
A. Bocheńska ◽  
M. Kwiatkowska ◽  
A. Pomianowski ◽  
T. Monowid ◽  
Z. Adamiak

Abstract EEG recording is used in veterinary medicine as a diagnostic tool to support clinical diagnosis of idiopathic epilepsy and to identify focal seizure activity. This retrospective study was designed to compare EEG procedures in 23 dogs with idiopathic epilepsy before and after phenobarbital treatment. Differences among standard deviations for particular bands were significant. During phenobarbital treatment the delta band decreased.


2017 ◽  
Vol 13 (1) ◽  
Author(s):  
Tariku Jibat Beyene ◽  
Amanuel Eshetu ◽  
Amina Abdu ◽  
Etenesh Wondimu ◽  
Ashenafi Feyisa Beyi ◽  
...  

2016 ◽  
Vol 25 (4) ◽  
pp. 194-198
Author(s):  
Ana Maria Gheorghiu ◽  
◽  
Raida Oneata ◽  
Mihai Bojinca ◽  
Rucsandra Dobrota ◽  
...  

Background. Semi-quantitative nailfold capillaroscopy (NFC) scoring represents a promising tool for assessing disease activity, severity and change in systemic sclerosis (SSc), however there is no consensus yet over which capillaroscopy abnormalities should be analyzed and how. Objective. Investigation of the reliability of the qualitative and semi-quantitative scoring of NFC assessment between two raters and test-retest for each rater in a SSc cohort. Methods. This is a single-center pilot study where 2 raters assessed the NFC images of 48 consecutive patients with SSc. Data were analyzed in 3 ways: 1. qualitatively by “normal”/“abnormal” category; 2. qualitatively by the following categories: “early”, “active”, “late” SSc patterns, “normal”, and unclassifiable in any pattern, and step; 3. Semi-quantitatively by calculating the mean score for capillary loss, disorganization of the microvascular array, giant capillaries, microhaemorrhages and capillary ramifications and combinations of giant capillaries and microhaemorrhages (as a surrogate for vascular activity). Disorganization and ramifications (surrogate for vascular damage) were also assessed. Variables for all steps were calculated for all fingers and for each finger. Inter-rater/intra-rater agreement was assessed by Cohen’s kappa coefficients for qualitative variables and by intraclass correlation coefficients (ICC) for mean score values of abnormalities. Results. Inter-rater reliability ranged from good to excellent agreement for mean score values of abnormalities in all fingers (ICC coefficients 0.745 to 0.897) and was excellent for activity (ICC coefficient of 0.923) and damage combinations (ICC coefficient of 0.918). Assessment of abnormalities in a qualitative manner (normal/abnormal or with capillaroscopy patterns) showed weaker inter-rater agreement than the semi-quantitative assessment (k coefficient <0.7). Intra-rater variability was good to excellent for mean score values of abnormalities and activity and damage combinations in all fingers and separate fingers for both raters; for qualitative assessment, only one of the raters had good test-retest reliability. Conclusion. Reliability of NFC assessment is essential in SSc trials/clinical practice to ensure quality of data. This pilot study demonstrates very good reliability between raters of the semi-quantitative NFC assessment in a SSc cohort. Combinations of NFC abnormalities had very good reliability and might be preferred because they are less time consuming.


2012 ◽  
Vol 2 (0) ◽  
pp. 12 ◽  
Author(s):  
Karen Ma ◽  
Rachel Babij ◽  
Etty Cortés ◽  
Jean-Paul G. Vonsattel ◽  
Elan D. Louis

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