scholarly journals Evaluation of sural nerve automated nerve conduction study in the diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus

2016 ◽  
Vol 2 ◽  
pp. 390-393 ◽  
Author(s):  
Georgia Chatzikosma ◽  
Kalliopi Pafili ◽  
Maria Demetriou ◽  
Dimitrios Papazoglou ◽  
Konstantinos Vadikolias ◽  
...  
2018 ◽  
Vol 5 (2) ◽  
pp. 380 ◽  
Author(s):  
Gurinder Mohan ◽  
Manish Chandey ◽  
Anusha Monga ◽  
Parik Dev

Background: Diabetes mellitus is known for its complications such as retinopathy, neuropathy and nephropathy. Diabetic neuropathy is one of the devastating complication associated with diabetes mellitus. The objective of this study was to detect sensory motor neuropathy in type 2 Diabetes mellitus by clinical examination and nerve conduction study and to correlate clinical features of peripheral neuropathy with nerve conduction study in Type 2 Diabetes mellitus.Methods: This study was undertaken to study types of neuropathy in type 2 diabetes and to correlate clinical features of peripheral neuropathy with nerve conduction study in type 2 diabetes mellitus.100 patients with diabetes whose onset of diabetes mellitus after age of 30 years and duration of diabetes 5 years or more visiting SGRDIMSR, Vallah, Amritsar were subjected to nerve conduction study to find out peripheral neuropathy.Results: Eight four percentage patients were found to have neuropathy on NCS whereas only 61% of patients were found to have neuropathy on clinical examination and detection rate with NCS was statistically significant (p <0.001) as compared to clinical examination.Conclusions: NCS helps in early detection of neuropathy and most common form of diabetic neuropathy is distal symmetrical polyneuropathy.


2016 ◽  
Vol 23 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Farah N. Abass ◽  
Moshtak Abdul-Atheem ◽  
Hanan F. Aswad

AbstractBackground and aims: This study aims to evaluate the electroencephalographic and nerve conduction changes in type 2 diabetes mellitus (T2DM) patients with and without peripheral neuropathy (DPN) and to investigate the relationship with other variables such as age, gender, duration of the diabetes and the degree of metabolic control.Materials and methods: This was a cross-sectional study, including 100 patients with T2DM and 100 control subjects, aged 34 to 77 years. All patients enrolled in the study were subjected to full assessment, including: history, biochemical and electrophysiological tests.Results: The study found that patients with diabetic peripheral neuropathy (DPN) in comparison to patients without DPN and control subjects were older, had longer duration of diabetes and poorer glycemic control reflected by fasting blood glucose and glycated hemoglobin. The electrophysiological findings showed that patients with DPN have significant differences in nerve conduction study (NCS) parameters when compared to patients without DPN and control subjects in the form of axonal degeneration and demyelination. They also had abnormalities of the electroencephalogram (EEG) which are correlated with nerve conduction study severity.Conclusion: Routine NCS is an important method for evaluating DPN. Investigating sensory nerves of lower limbs is helpful in discovering the early stages of DPN when other tested nerves are normal. The F-wave can be used as a sensitive indicator for the early diagnosis of DPN and it can help to detect the subclinical lesions. EEG examination in diabetic patients with severe DPN is important in showing the defect in the central nervous system.


Author(s):  
Sonali Das Pradhan ◽  
Sumana Panja ◽  
Shiuli Roy ◽  
Saktipada Pradhan ◽  
Kaushik Samajdar

Background: Type 2 diabetic patients have a higher prevalence of thyroid disorders, particularly hypothyroidism.  Peripheral neuropathy is a common and disabling complication of diabetes mellitus. Peripheral nervous system involvement in hypothyroidism is also a well-documented fact. Nerve conduction studies are generally considered to be the most sensitive and reproducible in the assessment of peripheral neuropathies. This study helped to determine the prevalence of peripheral neuropathy in diabetic hypothyroid patients as well as to compare it in diabetic patients with or without hypothyroidism. It compared the onset latency, amplitude, conduction velocity and F- wave latency of some nerves in type 2 diabetes mellitus patients with or without hypothyroidism.Methods: With RMS, EMG, EP MARK-II, nerve conduction studies are done in 30 cases (type 2 diabetes mellitus patients with hypothyroidism) and 30 controls (type 2 diabetes mellitus patients of diabetes without hypothyroidism) respectively, attending the Diabetic Clinic and Biochemistry Laboratory of North Bengal Medical College.Results: Data were treated with Unpaired t-Test. The study reveals that type 2 diabetes mellitus patients with hypothyroidism have higher prevalence of peripheral neuropathy. There is statistically significant (p<0.00) decrease in motor nerve conduction study in both right and left median nerves in diabetic patients with hypothyroidism than in diabetic patients without hypothyroidism.Conclusions: All diabetic patients should be screened for early detection of hypothyroidism as type 2 diabetic patients with hypothyroidism have higher prevalence of peripheral neuropathy. The nerve conduction study remains the most reliable, accurate, and sensitive method to evaluate peripheral nerve function.


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