scholarly journals Association of Platelet Count and Plateletcrit with Nerve Conduction Function and Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus

Author(s):  
Yuqin Qian ◽  
Yaying Zeng ◽  
Qingxia Lin ◽  
Huanjie Huang ◽  
Wanli Zhang ◽  
...  
Author(s):  
Sonali Das Pradhan ◽  
Sumana Panja ◽  
Shiuli Roy ◽  
Saktipada Pradhan ◽  
Kaushik Samajdar

Background: Type 2 diabetic patients have a higher prevalence of thyroid disorders, particularly hypothyroidism.  Peripheral neuropathy is a common and disabling complication of diabetes mellitus. Peripheral nervous system involvement in hypothyroidism is also a well-documented fact. Nerve conduction studies are generally considered to be the most sensitive and reproducible in the assessment of peripheral neuropathies. This study helped to determine the prevalence of peripheral neuropathy in diabetic hypothyroid patients as well as to compare it in diabetic patients with or without hypothyroidism. It compared the onset latency, amplitude, conduction velocity and F- wave latency of some nerves in type 2 diabetes mellitus patients with or without hypothyroidism.Methods: With RMS, EMG, EP MARK-II, nerve conduction studies are done in 30 cases (type 2 diabetes mellitus patients with hypothyroidism) and 30 controls (type 2 diabetes mellitus patients of diabetes without hypothyroidism) respectively, attending the Diabetic Clinic and Biochemistry Laboratory of North Bengal Medical College.Results: Data were treated with Unpaired t-Test. The study reveals that type 2 diabetes mellitus patients with hypothyroidism have higher prevalence of peripheral neuropathy. There is statistically significant (p<0.00) decrease in motor nerve conduction study in both right and left median nerves in diabetic patients with hypothyroidism than in diabetic patients without hypothyroidism.Conclusions: All diabetic patients should be screened for early detection of hypothyroidism as type 2 diabetic patients with hypothyroidism have higher prevalence of peripheral neuropathy. The nerve conduction study remains the most reliable, accurate, and sensitive method to evaluate peripheral nerve function.


2018 ◽  
Vol 5 (2) ◽  
pp. 380 ◽  
Author(s):  
Gurinder Mohan ◽  
Manish Chandey ◽  
Anusha Monga ◽  
Parik Dev

Background: Diabetes mellitus is known for its complications such as retinopathy, neuropathy and nephropathy. Diabetic neuropathy is one of the devastating complication associated with diabetes mellitus. The objective of this study was to detect sensory motor neuropathy in type 2 Diabetes mellitus by clinical examination and nerve conduction study and to correlate clinical features of peripheral neuropathy with nerve conduction study in Type 2 Diabetes mellitus.Methods: This study was undertaken to study types of neuropathy in type 2 diabetes and to correlate clinical features of peripheral neuropathy with nerve conduction study in type 2 diabetes mellitus.100 patients with diabetes whose onset of diabetes mellitus after age of 30 years and duration of diabetes 5 years or more visiting SGRDIMSR, Vallah, Amritsar were subjected to nerve conduction study to find out peripheral neuropathy.Results: Eight four percentage patients were found to have neuropathy on NCS whereas only 61% of patients were found to have neuropathy on clinical examination and detection rate with NCS was statistically significant (p <0.001) as compared to clinical examination.Conclusions: NCS helps in early detection of neuropathy and most common form of diabetic neuropathy is distal symmetrical polyneuropathy.


2016 ◽  
Vol 2 ◽  
pp. 390-393 ◽  
Author(s):  
Georgia Chatzikosma ◽  
Kalliopi Pafili ◽  
Maria Demetriou ◽  
Dimitrios Papazoglou ◽  
Konstantinos Vadikolias ◽  
...  

Gene ◽  
2019 ◽  
Vol 702 ◽  
pp. 114-122 ◽  
Author(s):  
Hemat El-Sayed El-Horany ◽  
Mona Mohamed Watany ◽  
Rasha Youssef Hagag ◽  
Shimaa Hassan El-Attar ◽  
Mohamed Abdelaziz Basiouny

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