scholarly journals Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis

2012 ◽  
Vol 24 (1) ◽  
pp. 74 ◽  
Author(s):  
Takahito Chiba ◽  
Masakazu Takahara ◽  
Takeshi Nakahara ◽  
Shuji Fukagawa ◽  
Kenjiro Takei ◽  
...  
Keyword(s):  
Necrobiosis Lipoidica ◽  
Cutaneous Sarcoidosis ◽  
Systemic Sarcoidosis

scholarly journals Lupus pernio (Besnier-Tenneson syndrome): A rare form of sarcoidosis

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Amal Hubail ◽  
Roza Belkharoeva ◽  
Natalya Tepluk ◽  
Tatyana Belerosova
Keyword(s):  
Psychological Effects ◽  
Management Approach ◽  
Cutaneous Sarcoidosis ◽  
Rare Form ◽  
Rare Presentation ◽  
Lupus Pernio ◽  
Rare Manifestation ◽  
Systemic Sarcoidosis ◽  
Delay In Treatment ◽  
Demographic Features

Lupus pernio (LP) is a chronic non-life threatining type of cutaneous sarcoidosis that can be related to chronic fibrotic sarcoidosis, hyperglobulinemia and hypercalcemia. The aim of this case report is to evaluate the clinical and demographic features of cutaneous sarcoidosis mainly presenting with a rare manifestation of LP. In this paper we report a case of systemic sarcoidosis presenting with LP and a review of the available literature. LP is a rare presentation with infiltrated erythematoviolaceous plaques affecting the nose. We address the main management approach, and possible association with an underlying systemic sarcoidosis. LP is a rare but chronic manifestation of systemic sarcoidosis that needs to be treated in order to prevent cosmetic defects and psychological effects. It is important to recognize such a condition early in order to avoid a delay in treatment and worsening of the condition, both physically and psychologically. Further research regarding the diagnostic approach and management is required to understand this condition thoroughly.

Systemic Sarcoidosis Revealed by Axillary Electrolysis

2015 ◽  
Vol 19 (4) ◽  
pp. 404-406 ◽  
Author(s):  
Meggie Morand ◽  
Solange Beauregard ◽  
Steve Mathieu
Keyword(s):  
Clinical Manifestations ◽  
Skin Lesions ◽  
Hair Removal ◽  
Granulomatous Disease ◽  
Cutaneous Sarcoidosis ◽  
Systemic Sarcoidosis ◽  
Histopathologic Findings

Background: Sarcoidosis is a noncaseating granulomatous disease that affects a large variety of organs and tissues. Skin sarcoidosis is commonly found in scar and tattooed tissues. Objective: To report this particular case of sarcoidosis following electrolysis hair removal. Method: We report the case of a woman who developed sarcoidosis years after axillary electrolysis hair removal. Results: The diagnosis of cutaneous sarcoidosis was suggested by the clinical manifestations and confirmed by histopathologic findings. Conclusion: Sarcoidosis should be considered during the investigation of skin lesions occurring in scar or traumatized tissue.

Necrobiosis Lipoidica Mimicking Cutaneous Sarcoidosis Finally Treated With an Intralesional Injection of Corticosteroid: A Case Report

2019 ◽  
Vol 19 (1) ◽  
pp. 92-94
Author(s):  
Mohamad Goldust ◽  
Ghasem Rahmatpour Rokni ◽  
Jeffrey Weinberg ◽  
Leon Kircik ◽  
Martine Bagot ◽  
...  
Keyword(s):  
Case Report ◽  
Intralesional Injection ◽  
Necrobiosis Lipoidica ◽  
Cutaneous Sarcoidosis

scholarly journals Unusual presentation and successful treatment of necrobiosis lipoidica in a 15-year-old girl

2019 ◽  
Vol 3 (3) ◽  
pp. 219-222
Author(s):  
Allison L Limmer ◽  
Levi C Holland ◽  
Annabelle L Garcia
Keyword(s):  
Glucose Intolerance ◽  
Granulomatous Inflammation ◽  
Giant Cells ◽  
Diabetic Patients ◽  
Thyroid Disorder ◽  
Necrobiosis Lipoidica ◽  
Clinical Context ◽  
Cutaneous Sarcoidosis ◽  
Topical Tacrolimus ◽  
The Right

Necrobiosis lipoidica (NL) is a rare, granulomatous skin disease with a predilection for diabetic patients. NL can present both histopathologically and clinically in a similar fashion to other granulomatous dermatoses such as granuloma annulare, necrobiotic xanthogranuloma, and cutaneous sarcoidosis. When NL is suspected in patients without glucose intolerance, affirmative diagnosis can be difficult, and other comorbidities may be probed, as NL has been associated with conditions such as hypertension, dyslipidemia, and thyroid disorders. Familial disease has also been reported.In the following case report, we discuss a 15-year-old girl who presented with a new, single, pink atrophic plaque of the right pretibial region. Biopsy showed palisaded granulomatous inflammation within the dermis, absent dermal mucin, and rare multinucleated giant cells. This histopathologic description combined with the clinical context led to the diagnosis of necrobiosis lipoidica. The patient developed another similar lesion on the left anterior shin over the next 1.5 years which was also approached as necrobiosis lipoidica. The lesions were treated with intralesional triamcinolone acetonide and topical tacrolimus. Both lesions are now resolved with only mild atrophy of the affected areas. To date, the patient’s labs have shown no evidence of glucose intolerance, hyperlipidemia, or thyroid disorder.

scholarly journals Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept

2016 ◽  
Vol 62 (8) ◽  
pp. 718-720 ◽  
Author(s):  
Marcella Amaral Horta Barbosa Vieira ◽  
Maria Isabel Ramos Saraiva ◽  
Larissa Karine Leite da Silva ◽  
Rafael Cavanellas Fraga ◽  
Priscila Kakizaki ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Skin Lesion ◽  
Negative Staining ◽  
Cutaneous Sarcoidosis ◽  
Cutaneous Involvement ◽  
Acid Fast Bacilli ◽  
Granulomatous Dermatitis ◽  
Systemic Sarcoidosis

Summary We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.

scholarly journals Cutaneous sarcoidosis with protean manifestations: a rare case report

2019 ◽  
Vol 5 (2) ◽  
pp. 437
Author(s):  
Avinash Pravin ◽  
Shreya Srinivasan ◽  
Jayakar Thomas
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Rare Case ◽  
Unknown Origin ◽  
Granulomatous Disease ◽  
Skin Involvement ◽  
Cutaneous Sarcoidosis ◽  
Rare Case Report ◽  
Systemic Manifestations ◽  
Systemic Sarcoidosis

<p class="abstract">Sarcoidosis is a multisystem granulomatous disease of unknown origin. The lung is the most commonly affected organ, but skin is frequently involved. Skin involvement is important because it may be the presenting sign of systemic sarcoidosis. Here, we report a rare case of sarcoidosis with systemic manifestations, in a 39 year old male patient.</p>

scholarly journals Manifestations of Besnier-Boeck-Schaumann sarcoidosis on skin

2020 ◽  
pp. 83-86
Author(s):  
V. G. Akimov
Keyword(s):  
Differential Diagnosis ◽  
Erythema Nodosum ◽  
Diagnosis And Treatment ◽  
Unknown Etiology ◽  
Cutaneous Sarcoidosis ◽  
Clinical Forms ◽  
Lupus Pernio ◽  
Multisystemic Disease ◽  
Nodular Sarcoidosis ◽  
Systemic Sarcoidosis

Besnier-Boeck-Schaumann sarcoidosis is a multisystemic disease of unknown etiology. Only about 25 % of patients have cutaneous involvement. Every patient with cutaneous sarcoidosis should be evaluated for possible systemic sarcoidosis. This article contains descriptions and original images of clinical forms of the disease: miliary sarcoidosis, circinate sarcoidosis, nodular sarcoidosis, angiolupoid (Brocq-Potrier), lupus pernio (Besnier-Tennesson), erythema nodosum, subcutaneous sarcoidosis (Darier-Roussy). Differential diagnosis and treatment of patients are discussed.

scholarly journals Cutaneous Sarcoidosis- A Report of Two Intriguing Cases

2020 ◽  
Author(s):  
R Mathumathy ◽  
S Murugan ◽  
S Adikrishnan ◽  
R Sivayogana
Keyword(s):  
Histopathological Examination ◽  
Corticosteroid Treatment ◽  
Skin Involvement ◽  
Lupus Vulgaris ◽  
Cutaneous Sarcoidosis ◽  
Noncaseating Granuloma ◽  
Systemic Involvement ◽  
Cutaneous Tuberculosis ◽  
Systemic Sarcoidosis ◽  
Systemic Symptoms

Sarcoidosis is an inflammatory disease which leads to formation of noncaseating granuloma in the affected organs like lungs, lymph nodes and less commonly the skin. Cutaneous sarcoidosis occurs in about 20-35% of individuals with systemic sarcoidosis. Skin involvement serves as an early marker and may be the presenting sign of systemic sarcoidosis. Wide variety of morphological forms of cutaneous sarcoidosis is known to occur simulating several other dermatoses. Isolated skin involvement is very rare. Histopathological examination and special stains plays an important role in ruling out other granulomatous conditions like cutaneous tuberculosis, leprosy, foreign body granuloma and granuloma annulare from sarcoidosis. Corticosteroids remain the main cornerstone in the treatment of cutaneous sarcoidosis. Here, the authors reported two interesting cases of cutaneous sarcoidosis without systemic involvement, of which one presented as micropapular sarcoidosis and the other was mimicking lupus vulgaris. Both of them responded well to corticosteroid treatment and are in regular monitoring for development of systemic symptoms. Informed consent was obtained was obtained from both the patients.

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