Narrow-band UVB for pretibial (necrobiosis lipoidica-like) involvement of cutaneous sarcoidosis: a promising therapeutic option

2017 ◽  
Vol 27 (5) ◽  
pp. 537-539
Author(s):  
Keiko Kuroda ◽  
Toshihisa Hamada ◽  
Mariko Shiomi ◽  
Keiji Iwatsuki
Endoscopy ◽  
2019 ◽  
Vol 51 (03) ◽  
pp. 253-260 ◽  
Author(s):  
Toshio Kuwai ◽  
Takuya Yamada ◽  
Tatsuya Toyokawa ◽  
Hiroaki Iwase ◽  
Tomohiro Kudo ◽  
...  

Background Cold polypectomy has been increasingly used to remove diminutive colorectal polyps. We evaluated the local recurrence rate of diminutive polyps at the 1-year follow-up after cold forceps polypectomy (CFP). Methods In a prospective, multicenter, observational cohort study, patients with diminutive colorectal polyps ( ≤ 5 mm) were treated by CFP using jumbo forceps followed by magnified narrow-band imaging (NBI). Patients were assessed for local recurrence at 1-year follow-up. Risk factors associated with local recurrence were analyzed using logistic regression analysis. Results Overall, 955 lesions were resected in 471 patients who completed the 1-year follow-up. The endoscopic complete resection rate was 99.4 %. Immediate and delayed bleeding occurred in 0.8 % and 0.2 % of cases, respectively, with no perforations observed. Local recurrence occurred in 2.1 % of cases at the 1-year follow-up. Univariable analyses indicated that polyps > 3 mm (P < 0.01) and immediate bleeding (P = 0.04) were significantly associated with local recurrence. A trend was observed for patients ≥ 65 years (P = 0.06) and fractional resection (P = 0.09). Multivariable analyses confirmed that lesions > 3 mm were significantly associated with local recurrence (odds ratio 3.4, P = 0.02). Conclusions CFP with jumbo forceps followed by NBI-magnified observation had a low local recurrence rate and is an acceptable therapeutic option for diminutive colorectal polyps. Although we recommend limiting the use of CFP with jumbo forceps to polyps ≤ 3 mm in size, future comparative studies are needed to make recommendations on cold polypectomy using either forceps or snares as the preferred approach for diminutive polyp resection.


2019 ◽  
Vol 19 (1) ◽  
pp. 92-94
Author(s):  
Mohamad Goldust ◽  
Ghasem Rahmatpour Rokni ◽  
Jeffrey Weinberg ◽  
Leon Kircik ◽  
Martine Bagot ◽  
...  

2019 ◽  
Vol 3 (3) ◽  
pp. 219-222
Author(s):  
Allison L Limmer ◽  
Levi C Holland ◽  
Annabelle L Garcia

Necrobiosis lipoidica (NL) is a rare, granulomatous skin disease with a predilection for diabetic patients. NL can present both histopathologically and clinically in a similar fashion to other granulomatous dermatoses such as granuloma annulare, necrobiotic xanthogranuloma, and cutaneous sarcoidosis. When NL is suspected in patients without glucose intolerance, affirmative diagnosis can be difficult, and other comorbidities may be probed, as NL has been associated with conditions such as hypertension, dyslipidemia, and thyroid disorders. Familial disease has also been reported.In the following case report, we discuss a 15-year-old girl who presented with a new, single, pink atrophic plaque of the right pretibial region. Biopsy showed palisaded granulomatous inflammation within the dermis, absent dermal mucin, and rare multinucleated giant cells. This histopathologic description combined with the clinical context led to the diagnosis of necrobiosis lipoidica. The patient developed another similar lesion on the left anterior shin over the next 1.5 years which was also approached as necrobiosis lipoidica. The lesions were treated with intralesional triamcinolone acetonide and topical tacrolimus. Both lesions are now resolved with only mild atrophy of the affected areas. To date, the patient’s labs have shown no evidence of glucose intolerance, hyperlipidemia, or thyroid disorder.


2012 ◽  
Vol 24 (1) ◽  
pp. 74 ◽  
Author(s):  
Takahito Chiba ◽  
Masakazu Takahara ◽  
Takeshi Nakahara ◽  
Shuji Fukagawa ◽  
Kenjiro Takei ◽  
...  

1966 ◽  
Vol 24 ◽  
pp. 188-189
Author(s):  
T. J. Deeming

If we make a set of measurements, such as narrow-band or multicolour photo-electric measurements, which are designed to improve a scheme of classification, and in particular if they are designed to extend the number of dimensions of classification, i.e. the number of classification parameters, then some important problems of analytical procedure arise. First, it is important not to reproduce the errors of the classification scheme which we are trying to improve. Second, when trying to extend the number of dimensions of classification we have little or nothing with which to test the validity of the new parameters.Problems similar to these have occurred in other areas of scientific research (notably psychology and education) and the branch of Statistics called Multivariate Analysis has been developed to deal with them. The techniques of this subject are largely unknown to astronomers, but, if carefully applied, they should at the very least ensure that the astronomer gets the maximum amount of information out of his data and does not waste his time looking for information which is not there. More optimistically, these techniques are potentially capable of indicating the number of classification parameters necessary and giving specific formulas for computing them, as well as pinpointing those particular measurements which are most crucial for determining the classification parameters.


1966 ◽  
Vol 24 ◽  
pp. 170-180
Author(s):  
D. L. Crawford

Early in the 1950's Strömgren (1, 2, 3, 4, 5) introduced medium to narrow-band interference filter photometry at the McDonald Observatory. He used six interference filters to obtain two parameters of astrophysical interest. These parameters he calledlandc, for line and continuum hydrogen absorption. The first measured empirically the absorption line strength of Hβby means of a filter of half width 35Å centered on Hβand compared to the mean of two filters situated in the continuum near Hβ. The second index measured empirically the Balmer discontinuity by means of a filter situated below the Balmer discontinuity and two above it. He showed that these two indices could accurately predict the spectral type and luminosity of both B stars and A and F stars. He later derived (6) an indexmfrom the same filters. This index was a measure of the relative line blanketing near 4100Å compared to two filters above 4500Å. These three indices confirmed earlier work by many people, including Lindblad and Becker. References to this earlier work and to the systems discussed today can be found in Strömgren's article inBasic Astronomical Data(7).


1997 ◽  
Vol 161 ◽  
pp. 611-621
Author(s):  
Guillermo A. Lemarchand ◽  
Fernando R. Colomb ◽  
E. Eduardo Hurrell ◽  
Juan Carlos Olalde

AbstractProject META II, a full sky survey for artificial narrow-band signals, has been conducted from one of the two 30-m radiotelescopes of the Instituto Argentino de Radioastronomía (IAR). The search was performed near the 1420 Mhz line of neutral hydrogen, using a 8.4 million channels Fourier spectrometer of 0.05 Hz resolution and 400 kHz instantaneous bandwidth. The observing frequency was corrected both for motions with respect to three astronomical inertial frames, and for the effect of Earths rotation, which provides a characteristic changing signature for narrow-band signals of extraterrestrial origin. Among the 2 × 1013spectral channels analyzed, 29 extra-statistical narrow-band events were found, exceeding the average threshold of 1.7 × 10−23Wm−2. The strongest signals that survive culling for terrestrial interference lie in or near the galactic plane. A description of the project META II observing scheme and results is made as well as the possible interpretation of the results using the Cordes-Lazio-Sagan model based in interstellar scattering theory.


1968 ◽  
Vol 11 (4) ◽  
pp. 811-816 ◽  
Author(s):  
Maurice I. Mendel

Thirty infants, ranging in age from 4 to 11 months, were tested with five different recorded sounds that varied in bandwidth and temporal configuration: a continuous band of white noise, the same band of noise interrupted twice per second, the crinkling of onionskin paper, a narrow band of noise centered at 3000 Hz, and a warbled 3000 Hz tone. With loudness and duration of the stimuli held constant, more responses occurred to sounds composed of a broadband spectrum than to those of a limited bandwidth. Temporal configuration of the sound had no effect on the number of responses elicited.


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