scholarly journals Prevalence of Bacterial Pathogens in Aseer Region, Kingdom of Saudi Arabia: Emphasis on Antimicrobial Susceptibility of Staphylococcus aureus

2011 ◽  
Vol 26 (5) ◽  
pp. 368-369 ◽  
Author(s):  
Mohamed E. Hamid,
2016 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Ibrahim Al Balawi ◽  
Palanisamy Amirthalingam ◽  
Abdullah Abdul Khalig Alyoussef ◽  
Osama Salih Mohammed ◽  
Hyder Oman Mirghani ◽  
...  

The present study aimed to investigate the antibiotic susceptibility pattern of Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) in isolated wound cultures of the patients admitted in King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. A retrospective cohort study of 54 patients admitted with wound infections in the surgical department. Ethics committee approval was granted by the University of Tabuk and King Khalid Hospital, Kingdom of Saudi Arabia. Fifty-four adult patients (&gt;18 years old) diagnosed with moderate to severe skin and soft tissue infections were included in the study. 26 patients with isolated cultures of MRSA were compared with 28 patients with Methicillin-sensitive <em>Staphylococcus aureus</em> (MSSA) isolated cultures using Graph pad prism 4.0 version statistical databases. Overall, there was no significant difference in sensitivity (P = 0.2445) and resistance (P = 0.4215) between MRSA and MSSA cultures. However, it is interesting findings that Oxacillin and Fusidic acid had higher resistance in MRSA isolated cultures compared MSSA culture, on the other hand, Linezolid, Tigecycline and Nitrofurantoin shows 100% sensitivity in both MRSA and MSSA isolates. No significant difference between male and female regarding the sensitivity (P = 0.0638) and resistance (P = 0.3638). The current study emphasizes that Tigecycline, Nitrofurantoin and Fusidic acid were the best drugs in both MRSA and MSSA isolates. While, oxacillin showed 100% resistance to MRSA; but retain its efficacy on MSSA isolates.


2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Aynalem Mohammed ◽  
Mengistu Endris Seid ◽  
Teklay Gebrecherkos ◽  
Moges Tiruneh ◽  
Feleke Moges

Background.The widespread uses of antibiotics, together with the length of time over which they have been available, have led to the emergence of resistant bacterial pathogens contributing to morbidity and mortality. This study was aimed to assess bacterial isolates and their drug susceptibility patterns from inpatients and outpatients with pus and/or wound discharge.Methods.A cross-sectional study was conducted at the University of Gondar Referral Hospital from March to May, 2014. Wound swab samples were collected from each study participant and inoculated into appropriate media. The bacterial pathogens were identified using standard microbiological methods. Antimicrobial susceptibility tests were performed using disk diffusion technique following Kirby-Bauer method.Results.A total of 137 study subjects were included in the study with bacterial isolation rate of 115 (83.9%). Of all, 81 (59.1%) were males. Seventy-seven (57%) of the isolates were Gram-negative and 59 (43%) were Gram-positive. From the total isolates,Staphylococcus aureuswas the most predominant isolate 39/115 (34%) followed by Klebsiella species (13%), coagulase negative staphylococci spp. (12%) andPseudomonas aeruginosa. Gram-positive isolates were resistant to ampicillin (86.4%), amoxicillin (83%), penicillin (81.3%), oxacillin (74.6%), and tetracycline (59.4%), while Gram-negative isolates were resistant to amoxicillin (97.4%), ampicillin (94.8%), tetracycline (72.7%), trimethoprim/sulfamethoxazole (66%), and chloramphenicol (54.5%).Conclusion. High prevalence of bacterial isolates was found,Staphylococcus aureusbeing the most dominant. High rates of multiple drug resistance pathogens to the commonly used antimicrobial agents were isolated. Therefore, concerned bodies should properly monitor the choice of antibiotics to be used as prophylaxis and empiric treatment in the study area.


Author(s):  
Ibrahim Al Balawi ◽  
Palanisamy Amirthalingam ◽  
Abdullah Abdul Khalig Alyoussef ◽  
Osama Salih Mohammed ◽  
Hyder Oman Mirghani ◽  
...  

The present study aimed to investigate the antibiotic susceptibility pattern of Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) in isolated wound cultures of the patients admitted in King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. A retrospective cohort study of 54 patients admitted with wound infections in the surgical department. Ethics committee approval was granted by the University of Tabuk and King Khalid Hospital, Kingdom of Saudi Arabia. Fifty-four adult patients (&gt;18 years old) diagnosed with moderate to severe skin and soft tissue infections were included in the study. 26 patients with isolated cultures of MRSA were compared with 28 patients with Methicillin-sensitive <em>Staphylococcus aureus</em> (MSSA) isolated cultures using Graph pad prism 4.0 version statistical databases. Overall, there was no significant difference in sensitivity (P = 0.2445) and resistance (P = 0.4215) between MRSA and MSSA cultures. However, it is interesting findings that Oxacillin and Fusidic acid had higher resistance in MRSA isolated cultures compared MSSA culture, on the other hand, Linezolid, Tigecycline and Nitrofurantoin shows 100% sensitivity in both MRSA and MSSA isolates. No significant difference between male and female regarding the sensitivity (P = 0.0638) and resistance (P = 0.3638). The current study emphasizes that Tigecycline, Nitrofurantoin and Fusidic acid were the best drugs in both MRSA and MSSA isolates. While, oxacillin showed 100% resistance to MRSA; but retain its efficacy on MSSA isolates.


2021 ◽  
Vol 3 (3) ◽  
pp. 221-226
Author(s):  
Abir Ben Ashur ◽  
◽  
Hamida El Magrahi ◽  
Asma Elkammoshi ◽  
Hiba Alsharif ◽  
...  

Introduction: Urinary tract infections (UTI) are one of the most common human bacterial infections encountered by physicians. The risk of resistant microbes is emerging as a result of the overuse of antibiotics treatments. The presence of pathogens with increased resistance to antimicrobial agents makes UTIs difficult to treat. This study was aimed at determining the prevalence of the pathogens that cause UTIs, as well as the antibiotic susceptibility of these isolates. Materials and methods: This prospective study was conducted from February 2020 to April 2020; a total number of 200 urine samples were collected from patients who daily attended TMC Libya. Bacterial pathogens were determined by bacteriological culture methods and Antimicrobial susceptibility testing was done by using the disc diffusion method. Results: Out of 200 samples, 110 cases had a positive culture. The dominant bacterial pathogens were Gram-negative that being with Escherichia coli (49, 55.68%), followed by Klebsiella pneumonia (18, 20.46%), Pseudomona aeruginosa (9, 10.23%), Proteus mirabilis (8, 9.09%), Enterobacter aerogenes (2, 2.27%), Citrobacter freundii (2, 2.27%). Gram-positive bacteria were Staphylococcus aureus 20 (90.91%) followed by S. saprophyticus (2, 9.01%) of the isolate’s strains. The isolated uropathogen showed increased levels of resistance to antibiotics. Where the Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus indicated the highest antibiotic resistance to Nitrofurantoin, Sulfamethoxazole/trimethoprim, Tetracycline, Ciprofloxacin, Metronidazole and also revealed the most sensitivity to Cefixime followed by doxycycline and ceftriaxone. Conclusions: The obtained results emphasized the emergence of highly resistant bacteria to most of the tested antimicrobials and propose the need for physicians to change their treatment pattern depending on antimicrobial susceptibility results.


2018 ◽  
Vol 12 (31) ◽  
pp. 747-753 ◽  
Author(s):  
Badger-Emeka Lorina ◽  
Abdulhadi Al-Sultan Abdulrahman ◽  
Sami Alrashed Abdullatif ◽  
Sami Alhaddad Mohammed ◽  
Khalifah Al-Barjas Afnan

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Mohammed S. Al Ahmary ◽  
Ali S. Al Mastour ◽  
Wagih M. Ghnnam

Objectives. Tonsillitis is a common infection in all age groups, especially under the age of five. Organisms causing this condition vary from place to place. Our aim is to find out the main causative agents of this condition in our hospital. Patients and Methods. Fifty-two consenting patients who needed tonsillectomy in Khamis civil hospital, Kingdom of Saudi Arabia, between September 2006 and April 2007, were enrolled for the study. Swabs were taken from their inner surfaces and cultured for anaerobes and aerobes according to standard microbiological techniques. Results. Fifty-two patients, consisting of 30 males and 22 females were enrolled. Their mean age was 9.81±6.47. Nearly 65% of patients had positive cultures while 35% were negative. The commonest bacteria isolated were Staphylococcus aureus (44.1%); and Group B Streptococcus (35.3 %). Two Gram-negative bacteria, Klebsiella pneumoniae, (8.82%), and Pseudomonas aeruginosa (2.94 %), were also isolated. No anaerobe was isolated. Conclusion. Gram-positive cocci, consisting of Staphylococcus aureus and Group B Streptococcus (Streptococcus agalactiae), are the major causes of tonsillitis requiring surgery in our hospital. Antibiotic treatment of this condition should be directed largely against these organisms.


2018 ◽  
Vol 4 (3) ◽  
pp. 492-496
Author(s):  
Yousef Ahmed Alomi ◽  
Hussam Saad Almalki ◽  
Aisha Omar Fallatah ◽  
Awatif Faraj Alshammari ◽  
Nesreen Al-Shubbar

The national total parental nutrition program with an emphasis on pediatrics started before several ago at Ministry of health hospitals In Kingdom of Saudi Arabia. The program covered several regions and consisted from the foundation of Intravenous Admixture and preparation of pediatric parenteral nutrition to administration and follow up of patients outcomes. In addition to the prior system, the new initiative project with the standardized formulation of pediatric’s parenteral nutrition is the complementary project of the parental nutrition for pediatrics. The project initiated to prevent drug-related problems of parental nutrition, improve patient clinical outcome and reduce the unnecessary economic burden on the healthcare system. It is the new system in the Middle East and Gulf counties in additional to Saudi Arabia. The initiatives are the systemic implementation of standardized pediatrics formulation using management project tools of starting new idea until finding in the ground.


2018 ◽  
Vol 4 (3) ◽  
pp. 483-487
Author(s):  
Yousef Ahmed Alomi ◽  
Hussam Saad Almalki ◽  
Aisha Omar Fallatah ◽  
Awatif Faraj Alshammari ◽  
Nahedh Rashed Alotaibi

The general administration of pharmaceutical care started potential pharmacy practice program. The program is part of accreditation professional’s process of national and international regulations. The adult’s parenteral nutrition was one of the critical programs. The most healthcare professionals are not familiar with the new system. The new initiatives system adult’s standardized concentration formulation of total parental nutrition as complementary to the previous one. The new formulation consisted of all parental nutrition requirements based on national and international standards. The new system can be converted as computerized physician orders. The new initiatives may implement as project management model over one year or less than that’s. The new system prevents nutrition-related problems, and medication errors, and improve clinical outcomes of the adults’ population in the Kingdom of Saudi Arabia.


2019 ◽  
Vol 16 (4) ◽  
pp. 503-512
Author(s):  
Simeon S. Magliveras

Filipinos are a major part of the workforce in the Kingdom of Saudi Arabia with a population of almost one million. This article investigates the effects of gender segregation on Filipino workers and how they navigate their lives through systems imposed on them. In particular, it examines the Kafala system (administrative sponsoring system) used for recruiting migrant workers for GCC countries. This article suggests that contrary beliefs about gender segregation and dress codes, Filipinas found it empowering. However, this article also concludes that gender segregation and dress codes also lead to isolation and loneliness. In addition, it is concluded that the fate and contentment of the overseas Filipino workers are directly dependent on who sponsors them.


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