scholarly journals AN OBSERVATIONAL CLINICAL STUDY ON LIPID PROFILE CHANGES BEFORE AND AFTER SHODHNARTH SNEHPAN

2021 ◽  
Vol p5 (6) ◽  
pp. 3086-3089
Author(s):  
Anupriya Varma ◽  
Ashish Varma

Background: Snehan(oleation) has a great role in all Panchakarma procedures. The therapeutic procedure by which greasiness is imparted to the body using different kinds of fat (Ghrita, Tail, Vasa, Majja etc) is called Snehan. Snehpan where fat substances are given in increasing doses by Ayurveda physicians, patients may have a fear that it will increase their cholesterol levels, there is this belief that if you consume ghrita, oil etc, it will in- crease your cholesterol levels and also increases the risk of heart disease. We conducted lipid profile reports be- fore and after Shodhnarth Snehpan in 10 patients in Janseva Ayurvedic Hospital, Surendranagar, Gujarat, India. Objectives: to observe Lipid Profile changes before and after Shodhanarth Snehpan. Management and Out- come: S. cholesterol, Triglycerides, LDL, VLDL in all 10 patients were decreased. HDL however increased which is good cholesterol. Conclusion: The study requires a large group for more specific data. From this study, we can say Snehpan does not increase S.cholesterol levels. Keywords: Lipid profile changes, Shodhanarth snehpan.

2015 ◽  
Vol 1 (1) ◽  
pp. 29-32
Author(s):  
Mithileshwer Raut ◽  
Prashant Regmi ◽  
Saroj Prasad Ojha ◽  
Bharat Jha

BACKGROUND: Alcohol dependence syndrome (ADS) has become a global public health challenge because of its high prevalence and the concomitant increase in risk of liver disease, cardiovascular disease and premature death. Influence of alcohol use on lipid metabolism is well recognized. Investigations had been carried out in the earlier period on abnormal lipid profile as a risk factor for Coronary Heart disease (CHD). Patients of alcohol dependence usually have a consumption pattern of more heavy use. Therefore it is useful to study the lipid profile in patients of alcohol dependence, to understand the effects of increasing levels of consumption. METHODS: This cross-sectional study was conducted in TU Teaching Hospital. ADS patients were screened by the consultant psychiatrist using the Alcohol Use Disorder Identification Test (AUDIT) questionnaire. A total of 89 patients scored positive on the AUDIT as having alcohol-related problems and were included in the study. 89 ADS patients and 89 healthy controls both male and female were enrolled as participants. Blood Pressure and other anthropometric parameters were measured while fasting blood samples were analyzed for serum lipid profile. SPSS program was used to analyze data, t-test & Spearman's correlation coefficient was used to find correlation. RESULTS: Among the ADS cases 95% were current smokers. Mean age of cases and controls was 35.42±5.6 & 34.53±3.5 years respectively. The mean total cholesterol levels were found to be higher in cases (5.41±0.70) than controls (3.79±0.74) with a strong statistical significance (p<0.001). Also, Mean triglyceride (TG) levels (2.09±0.72), along with the mean HDL-cholesterol (1.66±0.40) and LDL-cholesterol levels (2.79±0.81) were also elevated in cases when compared to the control samples (p<0.001). CONCLUSION: This study has demonstrated definitive lipid profile changes in patients of alcohol dependence, with some correlation to the liver dysfunction. Alcohol causes alteration in various parameters of lipid metabolism including those which predispose to CHD. Low to moderate alcohol use over prolonged periods has been linked to have protective influence for development of coronary heart disease (CHD), through increase in high density lipoprotein cholesterol (HDL-C) levels. DOI: http://dx.doi.org/10.3126/acclm.v1i1.12312 Ann. Clin. Chem. & Lab. Med. 1(1) 2015: 29-32


2021 ◽  
Vol 8 (1) ◽  
pp. 043-048
Author(s):  
Ririn Handayani ◽  
Rizki Fitrianingtyas

Injectable DMPA contraception can cause changes in lipoprotein metabolism. Changes in fat metabolism occur because of the hormonal influence of progesterone, causing disruption of the balance of lipid profiles in the body. The change in serum lipid profile (trgliseride, total cholesterol, HDL and LDL) in long-term use of DMPA is a risk factor for atherosclerosis and cardiovascular disease. The purpose of this study was to look at the description of the lipid profile at 3 months injection acceptors. The design of the study was descriptive. The population in this study was 76, the number of samples that met the inclusion and exclusion criteria in this study was 30. Examination of the lipid profile was carried out with an enzymatic colorimetric (cholesterol oxidase method / CHOD PAP). The results of lipid profile examination showed that 13.33% had high cholesterol levels, 3.33% had high triglyceride levels, 13.33% had high HDL levels, 20% had high LDL levels and 3.33% have very high LDL levels. The conclusion of this study was long term use of DMPA injection contraception could cause changes in the lipid profile, so it is recommended for acceptors who want to use contraception in the long term to use MKJP as an option so as not to affect the fat profile in the body.


2017 ◽  
Vol 4 (1) ◽  
pp. 39-44
Author(s):  
Ni Made Restina Juliani ◽  
I Putu Oka Dharmawan ◽  
Putu Ayu Parwati

Introduction: Low Density Lipoprotein (LDL) is a type of low-density lipoprotein and the most widely transported cholesterol in the body. Increased levels of LDL in the body can be affected by genetics, age, gender, obesity, physical activity, lifestyle, drug consumption and smoking. Substances in a cigarette can cause an increase of LDL levels. Increased of LDL cholesterol levels can cause Coronary Heart Disease (CHD). The purpose of this research is to know the description of Low Density Lipoprotein (LDL) levels on smoker and non-smoker adolescent in Buyan Hamlet, Pancasari Village, Sukasada District, Buleleng Bali. Method: The type of this research is descriptive. This research was conducted in April-May 2017, which used fasting blood samples of 42 respondents. Result: From the average result of LDL level in smoker adolescent that is 134,91 mg/dL higher than the average of LDL level in non-smoker adolescent that is 74,90 mg/dL. The result of LDL cholesterol levels was determined by 21 smoker adolescent respondents with the close to optimal category (100-129 mg/dL) as many as 9 people (42,8%), and 12 people (57,3%) with worry category (130-159 mg/dL). Whereas in 21 non-smoker adolescent respondents obtained  result of LDL cholesterol level test with optimal category (<100 mg/dL) counted 18 people (87,71%) and 3 person (14,30%) with close to optimal category (100-129 mg/dL). Discussion: Based on the results of this research can be concluded that in smoker adolescent obtained LDL levels with close to optimal category and worrying whereas in non-smoker adolescents obtained LDL levels in the optimal category and close to optimal.


2012 ◽  
Vol 8 (3) ◽  
pp. 106
Author(s):  
Krisnansari Diah ◽  
Ariadne Tiara Hapsari ◽  
Evy Sulistyoningrum ◽  
Agus Prastowo

Background: Nowadays, cardiovascular disease caused by hypercholesterolemia has become the main cause of death. Propolis has been used widely to reduce plasma cholesterol levels.Objective: The aims of this research was to study the effect of propolis on lipid profile of hypercholesterolemic Sprague Dawley rats.Method: This was an experimental study with pre-post test. Twenty four (24) male Sprague Dawley rats aged 12-16 week old, weighing 125-200 g were allocated into 4 groups. Group I received standard meal + aquadest-gavage; group II received high cholesterol meal + PTU 0,01 + aquadest gavage; group III received high cholesterol meal + PTU 0,01 + 0,027 g propolis gavage; group IV received high cholesterol meal + PTU 0,01 + 0,054 g propolis gavage. Total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol levels before and after treatment were measured. The data were then analyzed with One Way Anova.Results: The study showed that there were no significant differences in changes of body weight. There were significant differences in total cholesterol levels between all groups of treatment. Triglyceride levels were significantly different among all groups, except between group I and IV. Furthermore, the HDL cholesterol levels of group I vs III and group I vs IV were significantly different. However, there were no differences found in LDL cholesterol levels among all groups of treatment.Conclusion: Provision of 0,027 g and 0,054 g propolis improve lipid profile (total cholesterol, triglyceride and HDL cholesterol levels) of hypercholesterolemic rats.


AYUSHDHARA ◽  
2021 ◽  
pp. 3104-3108
Author(s):  
Gupta Sudesh ◽  
Manhas Raman, Prasher Aarushi, Sharma Sakshi, Sharma Arun

Skin is the general covering of the entire external surface of the body. Because of a large number of its functions, the skin is regarded as an important organ of the body. There are so many skin disorders of which Tenia pedis is a very common fungal infection that affects a significantly large number of people globally. This fungal infection is called Athlete’s foot because it is commonly seen in athletes. In Ayurveda, various skin disorders are described under the heading of kshudraroga. A brief description about Kshudraroga has been given in many Ayurvedic classics. Alasa is a variety of Kshudraroga occurring in between the skin of toes manifesting with Kleda, Kandu, Daha and Ruja. Talisadi tailam mentioned in Sushruta Samhita is an excellent formulation prepared of drugs which are effective against this disease. Current study includes 30 patients from OPD Department of Shalya Tantra, Jammu Institute of Ayurveda and Research, Jammu and Sri Sain Charitable Hospital, Janipur, Jammu diagnosed to have Tenia pedis based on signs and symptoms. Therapeutic effect was evaluated before and after treatment. The present clinical study has shown symptoms of Kandu, Daha, Ruja, Kleda significantly reduced after application of Talisadi tailam.


Jurnal GIZIDO ◽  
2019 ◽  
Vol 11 (01) ◽  
pp. 1-7
Author(s):  
Nonce Nova Legi ◽  
Mirna Kawulusan ◽  
Marstevi Olivia Gedoan

Hypercholesterolemia is an increase in total cholesterol levels in the blood beyond the normal limits. Excess cholesterol levels in the blood will have an impact on degenerative diseases. Brown rice (oryza nivara) is a rice rich in vitamins, minerals and contain water soluble fiber that can help bind cholesterol, then throw it out of the body. Regular consumption of brown rice is very beneficial for health that can reduce levels of LDL. The aim of this research is to know the effectiveness of brown rice rice to total cholesterol level in hypercholesterolemia patient in Vilage Sea Pineleng District of Minahasa Regency. The type of this research is Quasi Eksperimen with One Group of Pretest and Posttest Design. The sample in this study is the entire population of hypercholesterolemia patients recorded in Posbindu Village Sea Pineleng District Minahasa regency that meets the inclusion criteria. Rice brown rice is given for 8 consecutive days every morning, day and night. Total cholesterol levels were measured before and after administration of brown rice. Data analysis using Paired t-test. The results showed that the total cholesterol level before the study was the highest of 360 mg / dl, the lowest was 216 mg / dl, and after the highest total cholesterol was 298 mg / dl, the lowest was 164 mg / dl. The result of statistical test shows that p = 0,019 (p <0,05), which means that there is difference of total cholesterol before and after giving of rice of red rice to hypercholesterolemia patient in Vilage Sea Pineleng Sub-district of Minahasa Regency.


Circulation ◽  
2001 ◽  
Vol 103 (suppl_1) ◽  
pp. 1369-1369
Author(s):  
Viktorina N Muratova ◽  
Syed S Islam ◽  
Emily C Spangler ◽  
Ellen W Demerath ◽  
William A Neal

P94 Background: Selective blood cholesterol screening of children based upon National Cholesterol Education Program (NCEP) guidelines of family history of premature cardiovascular disease (CVD) or parental hypercholesterolemia is inadequate in a population with high prevalence of coronary heart disease (CHD), low levels of cholesterol screening, low socio-economic status (SES) and diminished access to preventive health care. We hypothesize that universal cholesterol screening of pre-pubertal school children may be effective in identifying children and their parents with abnormal lipid levels in this high risk rural population. Fifth grade school children from seven rural Appalachian counties participated in a school based cholesterol screening program. Data on family history of premature CHD, anthropometric and blood pressure measurements, tobacco smoke exposure, dietary history and physical activity levels were collected at the time of screening. Seven hundred and nine 5 th grade students ( mean age 10.8 years) participated in the program. One hundred seventy four (24.5%) were considered presumptively dyslipidemic after non-fasting finger- stick (FS) cholesterol screening. Thirty six percent of these dyslipidemic children had a fasting lipid profile done. Dyslipidemia was confirmed in 37(59%) of these children. FS cholesterol levels were significantly correlated with fasting TC (r=0.80 p < 0.0001). Among confirmed dyslipidemic children, family history was not a good predictor of dyslipidemia (sensitivity 21.6%). Seventy nine parents of dyslipidemic children participated in fasting lipid profile assessment. Fifty two parents (67%) were dyslipidemic, most of them (79%) did not have a family history of premature CHD or hypercholesterolemia. FS cholesterol levels were also correlated with fasting TC of fathers (r=0.46 p=0.01), and mothers (r=0.32 p=0.02). Conclusion: Significant correlation exists between non-fasting FS cholesterol levels of children and subsequent fasting lipid profile of children and their parents. Family history has low sensitivity in predicting children with elevated serum cholesterol concentrations.


2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Rosalia N.H Lamanepa ◽  
Miftakhul Mualimah

ABSTRAKKolesterol menjadi ujung pangkal permasalahan munculnya berbagai penyakit dalam tubuh. Ada banyak cara yang dapat dilakukan untuk menangani kadar kolesterol, selain perawatan medis, pengobatan tradisional juga bisa dilakukan untuk mencegah dan menurunkan kadar kolesterol yang tinggi diantaranya buah alpukat. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian smoothie alpukat terhadap kadar kolesterol pada wanita menopause di kelas lansia BPM Ny “N”. Penelitian ini termasuk penelitian pre eksperimen dengan pendekatan One Group Pretest-Posttest Design. Populasi dalam penelitian ini adalah semua wanita menopause yang mengalami hiperkolesterolemia (kolesterol 200mg/dL) di Kelas Lansia BPM Ny “N” sebanyak 30 orang. Dengan sampel sebanyak 16 orang. Teknik sampel yang digunakan adalah purposive sampling. Hasil penelitian menunjukkan adanya pengaruh pemberian smoothie alpukat terhadap kadar kolesterol pada wanita menopause di kelas lansia BPM Ny “N” dengan persentase penurunan rata-rata kolesterol sebanyak 16.14%. Uji statistik menggunakan Uji T berpasangan dengan tingkat kepercayaan 95% didapatkan p-value α yaitu 0.000 0.05 yang artinya ada perbedaan signifikan antara kadar kolesterol sebelum dan sesudah mengkonsumsi smoothie alpukat pada wanita menopause.Dari hasil penelitian ini dapat disimpulkan bahwa smoothie alpukat efektif menurunkan kadar kolesterol pada wanita menopause dan dari hasil penelitian ini diharapkan masyarakat dapat menggunakan smoothie alpukat sebagai salah satu alternatif terapi untuk menurunkan kolesterol pada wanita menopause.Kata Kunci: Smoothie Alpukat, Kadar Kolesterol, Menopause ABSTRACTCholesterol becomes the root of the problem of the emergence of various diseases in the body. There are many ways that can be done to handle cholesterol levels, in addition to medical care, traditional medicine can also be done to prevent and lower high cholesterol levels such as avocados. This study aims to determine the effect of avocado smoothie on cholesterol levels in menopausal women in the elderly BPM Ny "N" class. This research includes pre experimental research with One Group Pretest-Posttest Design approach. The population in this study were all menopausal women who had hypercholesterolaemia (cholesterol 200mg / dL) in the elderly grade BPM Ny "N" as many as 30 people. With a sample of 16 people. The sample technique used is purposive sampling. The research instrument used was monitor cholesterol and observation sheet. The results showed the effect of giving avocado smoothie to cholesterol levels in menopausal women in the elderly class BPM Ny "N" with the percentage decrease in average cholesterol as much as 16.14%. Statistical test using paired T Test with 95% confidence level obtained p-value α that is 0.000 0.05 which means H0 rejected and H1 accepted. This means there is a significant difference between cholesterol levels before and after consuming avocado smoothie in menopausal women in the Elderly Class BPM Ny "N". From the results of this study is expected people can use avocado smoothie as one alternative therapy to lower cholesterol in menopausal women.Keywords: Avocado Smoothie, Cholesterol Level, Menopause


2021 ◽  
Vol p5 (4) ◽  
pp. 2896-2901
Author(s):  
Rakshitha Kumari ◽  
Niranjan Rao

Panchakarma therapy is the ideal line of treatment to maintain the state of health for a longer duration. It aims at the elimination of excessive Doshas from the body. Vamana karma is one of the Panchakarma procedure where in vomiting is induced by drugs and aims at the elimination of excessive Kapha and Pitta dosha from the body. Amavata is a Vyadhi where Kapha and Vata are predominantly involved. Its Udhbava Sthana is Amashaya and Vyaktha Sthana is Sandhi. Vamana is considered as best treatment for Kapha and its associated conditions. In Amavata mainly Kapha Sthana like Sandhi is affected. Langhana is considered as the prime line of treatment for Amavata. Vamana is considered under shodhana variety of Langhana. Normally, after Vamana patient does not complain of having any untowards like those patients after vomiting due to dehydration. This study was conduct- ed to evaluate the effect of vamana karma on serum electrolyte levels and access the safety of therapeutic vomiting. In this study, 20 patients diagnosed with Amavata were selected and subjected for Vamana karma. This study in- volves estimation of serum electrolyte levels before and after Vamana. The results are suggestive of safe applica- tion of the Vamana karma. Keywords: Amavata, Serum electrolytes, Vamana karma.


2020 ◽  
Vol 5 (2) ◽  
pp. 179
Author(s):  
Novi Dwi Yanti ◽  
Suryana Suryana ◽  
Yulia Fitri

World Health Organization has estimated that the main cause of death in degenerative diseases is coronary heart disease (CHD). Coronary heart disease can be caused by narrowing of the blood vessels due to high levels of fat in the blood. This is due to excessive intake of fat and carbohydrates, and not doing physical activity or the body is not moving. This study aims to determine the blood lipid profile of outpatients with coronary heart disease. This descriptive-analytic study was used as a case-control study design, with a sample of 64 outpatients. The study was conducted at the Meuraxa Hospital Banda Aceh in March 2019. Intake data were collected using the SQ-FFQ method and physical activity data using the PAL method, while HDL, LDL, and triglyceride data were obtained through secondary data from hospital medical records. The statistical test was used by the Chi-Square test. The results showed that there was an effect of fat intake on blood lipid profiles in coronary heart disease patients (p= 0,006 with OR= 4,80), and the effect of carbohydrate intake (p= 0,032 and OR= 2,96), on the contrary, physical activity (p= 0,130) with a lipid profile showed no association. In conclusion, the intake of fat and carbohydrates has an effect on blood lipid profiles, but physical activity does not affect the blood lipid profiles of patients with coronary heart disease. Suggestions, it is necessary to maintain a balance of consumption of foods that are high in fat, and it is necessary to do consultations regarding low-fat diets


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