scholarly journals Clinical and radiographical evaluation of the healing of large periapical lesions using triple antibiotic paste, photo activated disinfection and calcium hydroxide when used as root canal disinfectant

2014 ◽  
pp. e230-6 ◽  
Author(s):  
DA. Johns ◽  
JM. Varughese ◽  
K. Thomas ◽  
A. Abraham ◽  
EP. James ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Periapical Lesions ◽  
Triple Antibiotic Paste

Effect of triple antibiotic paste and calcium hydroxide on the rate of healing of periapical lesions: A systematic review

2021 ◽  
Vol 24 (4) ◽  
pp. 307
Author(s):  
NKiran Kumar ◽  
Biji Brigit ◽  
BS Annapoorna ◽  
SavithaB Naik ◽  
Seema Merwade ◽  
...  
Keyword(s):  
Systematic Review ◽  
Calcium Hydroxide ◽  
Periapical Lesions ◽  
Triple Antibiotic Paste

scholarly journals Erratum: Number of Dental Stem Cells on Root Canal Dentin after Application of Triple Antibiotic Paste or Calcium Hydroxide: An In Vitro Study

2019 ◽  
Vol 13 (02) ◽  
pp. e1-e1
Author(s):  
Konstantinos Gougousis ◽  
Dimitrios G. Giannakoulas ◽  
Vasiliki Taraslia ◽  
Anastasia Agrafioti ◽  
Ema Anastasiadou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
In Vitro Study ◽  
Vitro Study ◽  
Dental Stem Cells ◽  
Triple Antibiotic Paste ◽  
Root Canal Dentin

scholarly journals Assessment of Nitrofurantoin as an Experimental Intracanal Medicament in Endodontics

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Mewan Salahalddin A. Alrahman ◽  
Bestoon Muhammed Faraj ◽  
Kawa F. Dizaye
Keyword(s):  
Enterococcus Faecalis ◽  
Root Canal ◽  
Antibacterial Agent ◽  
Antibacterial Agents ◽  
Distilled Water ◽  
Human Teeth ◽  
Periapical Lesions ◽  
Complete Eradication ◽  
Colony Forming Unit ◽  
Triple Antibiotic Paste

Background and Objectives. Multiple antibacterial agents have been mixed and used as an intracanal medicament-like modified triple antibiotic paste (MTAP) to eliminate Enterococcus faecalis (EF), which has been most frequently identified in the cases of failed root canal treatment and periapical lesions. This study is aimed at using a single antibacterial agent, nitrofurantoin (Nit), as an experimental intracanal medicament paste against different clinical isolates of EF bacteria and at comparing its antimicrobial efficacy with MTAP. Materials and Methods. Three strains of EF (S1, S2, and S3) were clinically isolated. A total of 198 straight single-rooted human teeth were collected and divided randomly into three main groups: group N (Nit) (n=90), group M (MTAP) (n=90), and group W (distilled water) (n=18). The main groups were subdivided into three subgroups according to the strain of EF: in groups N and M, subgroups S1, S2, and S3 (n=30), while in group W, subgroups S1, S2, and S3 (n=6). Then, each subgroup of N and M was divided into five groups (n=6) according to the concentrations of Nit or MTAP (6.25, 12.5, 25, 50, and 100 mg/mL). The colony-forming unit (CFU) of EF from the canal lumen and dentinal chips was measured. Results. Nit could eradicate S1, S2, and S3 completely with concentrations of 6.25, 12.5, and 25 mg/mL, respectively, while MTAP showed complete eradication of the three strains only at 25 mg/mL. In all the groups, it was found that the CFU counts of EF in the dentinal chips were higher than those in the root canal lumen. Conclusion. At the concentration of 25 mg/mL, the Nit paste is effective in eradicating EF completely when it is used as an intracanal medicament.

scholarly journals Non-surgical management of periapical lesions with triple antibiotic paste: A case reports

2020 ◽  
Vol 2 ◽  
pp. 120-123
Author(s):  
Munish Singla ◽  
Iyana Garg ◽  
Vandana Goyal ◽  
Harleen Kaur ◽  
Litik Mittal
Keyword(s):  
Case Report ◽  
Surgical Management ◽  
Root Canal ◽  
Case Reports ◽  
Endodontic Treatment ◽  
Root Canal Treatment ◽  
Periapical Lesion ◽  
Present Case Report ◽  
Periapical Lesions ◽  
Triple Antibiotic Paste

Sterilization of root canal space is foremost for the success of the endodontic treatment which is usually carried out with intracanal irrigants and medicaments. Triple antibiotic paste (metronidazole, ciprofloxacin, and minocycline) is used to achieve sterilization and healing of periradicular area. In the present case report, the triple antibiotic paste was used for non-surgical management of periapical lesion for 3 weeks. After 3 weeks, the tooth became asymptomatic that was then obturated. Hence, it is confirmed that conventional root canal treatment, along with intracanal medicaments (triple antibiotic paste), can non-surgically manage the periapical lesions and further promotes healing.

scholarly journals Nonsurgical Clinical Management of Periapical Lesions Using Calcium Hydroxide-Iodoform-Silicon-Oil Paste

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Qusai Al Khasawnah ◽  
Fathi Hassan ◽  
Deeksha Malhan ◽  
Markus Engelhardt ◽  
Diaa Eldin S. Daghma ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Tooth Extraction ◽  
Rating Scale ◽  
Complete Healing ◽  
Permanent Teeth ◽  
Slow Phase ◽  
Rapid Phase ◽  
Periapical Lesions ◽  
Silicon Oil

Background. The study aim is to avoid tooth extraction by nonsurgical treatment of periapical lesion. It assesses healing progress in response to calcium hydroxide-iodoform-silicon oil paste (CHISP). Numeric Pain Rating Scale was used to validate the approach. Furthermore, CHISP was used to treat cystic lesions secondary to posttraumatic avulsion of permanent teeth. Materials and Methods. Over 200 patients with radicular cysts were treated with CHISP through the root canal. Radiographs were used to verify lesion size and position, ensure correct delivery to the site, and monitor the progress of bone healing in the lesion area. Ten males and 10 females were randomly selected for statistical assessment. Results. No severe pain, complications, or failure in cyst healing was reported. Complete healing was achieved in an average of 75 days. Furthermore, healing of radicular cyst secondary to posttraumatic tooth avulsion was successful. Conclusion. CHISP indicated an antiseptic effect, which enhanced and shortened healing time of periapical lesions. The less invasive procedure avoids tooth extraction and reduces bone resorption. Cyst management with CHISP can remedy failed root canal treatments. The results show a bone regenerative capacity of CHISP suggested in first rapid phase and a second slow phase.

scholarly journals Apical third enlargement of the root canal and its relationship with the repair of periapical lesions

2012 ◽  
Vol 06 (04) ◽  
pp. 385-388 ◽  
Author(s):  
Ronaldo Araújo Souza ◽  
João Costa Pinto Dantas ◽  
Paula Maciel Brandão ◽  
Suely Colombo ◽  
Maurício Lago ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Undergraduate Students ◽  
Root Canal ◽  
Endodontic Treatment ◽  
Exact Test ◽  
Periapical Lesions ◽  
Group I ◽  
Group Ii ◽  
Determinant Factor

ABSTRACTObjective: The purpose of this study was to evaluate if the apical third enlargement of root canal is the determinant factor for the repair of periapical lesions in endodontic treatment.Methods: Eighty upper and lower incisors, canines and premolars with periapical lesions were randomly divided in 2 groups and were treated by undergraduate students. Canals were instrumented with up to 3 files in group I (n = 40) and up to 4 files in group II (n = 40) 1 mm short of the apex and were filled with a calcium hydroxide dressing. After removing calcium hydroxide 14 days later, both groups were filled using the lateral condensation technique. In the 2-year follow-up, a few patients did not return, and some cases did not present conditions for accurate comparisons. Therefore, only 43 patients (24 in group I and 19 in group II) presented conditions for radiographic comparisons. Data were statistically analyzed using Fisher's exact test.Results: Comparison of the initial and follow-up radiographs showed that 22 out of 24 (91.67%) patients in group I and 17 out of 19 patients (89.47%) in group II showed repair. Statistical analysis revealed no significant differences between the groups (P>.05).Conclusion: The results of this study show that the apical third enlargement did not alter the outcome of endodontic treatment of teeth with periapical lesion performed by undergraduate students. (Eur J Dent 2012;6:385-388)

scholarly journals Comparison of Antibacterial Effects of Photodynamic Therapy, Modified Triple Antibiotic Paste and Calcium Hydroxide on Root Canals Infected With Enterococcus faecalis: An In Vitro Study

2019 ◽  
Vol 10 (5) ◽  
pp. S23-S29 ◽  
Author(s):  
Mohammad Asnaashari ◽  
Mohammad Jafar Eghbal ◽  
Amirali Sahba Yaghmayi ◽  
Mehdi Shokri ◽  
Saranaz Azari-Marhabi
Keyword(s):  
Photodynamic Therapy ◽  
Calcium Hydroxide ◽  
Enterococcus Faecalis ◽  
Root Canal ◽  
Control Group ◽  
Root Canals ◽  
Anterior Teeth ◽  
Triple Antibiotic Paste ◽  
Working Length

Introduction: A pivotal issue to achieve success in the treatment of the root canal is root canal disinfection. One of the most important bacteria that infect the root canal is Enterococcus faecalis. This study seeks to examine the effectiveness of 3 methods for disinfecting the root canal: photodynamic therapy, modified triple antibiotic paste (MTAP), and calcium hydroxide. Methods: Sixty-two single-rooted extracted anterior teeth were collected. After cleaning and disinfecting the teeth, their crowns were cut at the CEJ point. The root canals were shaped to the working length up to file F3 ProTaper (F1, F2, F3). EDTA 17% and sodium hypochlorite 2.5% were used for 5 minutes to wash and remove the smear layer, and then the apical foramen was sealed using composite. After that, the teeth were sterilized in an autoclave at 121°C for 15 minutes. Then 10 samples were taken randomly as the negative control. The remaining samples were immersed and cultivated in a suspension containing E. faecalis for 21 days. Then the samples were divided into 5 groups: 2 positive control groups, 1 group treated with the antibiotic paste with the concentration of 1 mg/mL, 1 group treated with calcium hydroxide, and 1 group treated with photodynamic therapy. Then, to collect the biofilm, the ProTaper file F4 was used. After that, the microbial suspension was provided and counting the colonies was carried out to compare the groups. Results: The findings indicated that the amount of CFU/mg of MTAP samples, including clindamycin, metronidazole, ciprofloxacin in the concentration of 1 mg/mL and photodynamic therapy and calcium hydroxide was lower than that in the control group. Antibiotic paste cleansed the root canal up to 99.9%. Photodynamic therapy reduced the amount of CFU/mg to 98.8%, and calcium hydroxide reduced the amount of CFU/mg to 94.13%. Conclusion: Using photodynamic therapy causes a reduction in the biofilm and inhibits the growth of the E. faecalis bacterium. In addition, in this study, MTAP with a concentration of 1 mg/mL was used, which expunged the bacteria completely. Meanwhile, calcium hydroxide had the weakest effect of all on the E. faecalis bacterium.

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