Effect of triple antibiotic paste and calcium hydroxide on the rate of healing of periapical lesions: A systematic review

2021 ◽  
Vol 24 (4) ◽  
pp. 307
Author(s):  
NKiran Kumar ◽  
Biji Brigit ◽  
BS Annapoorna ◽  
SavithaB Naik ◽  
Seema Merwade ◽  
...  
Keyword(s):  
Systematic Review ◽  
Calcium Hydroxide ◽  
Periapical Lesions ◽  
Triple Antibiotic Paste

scholarly journals Effectiveness of triple antibiotic paste as an intra-canal medication for the root canal treatment of non-vital teeth with apical periodontitis: A systematic review

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1627
Author(s):  
Ehab Abdel Hamid ◽  
Saied Abdel Aziz ◽  
Hany Samy Sadek ◽  
Ahmed Mohamed Ibrahim
Keyword(s):  
Systematic Review ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Apical Periodontitis ◽  
Root Canal Treatment ◽  
Effect Estimate ◽  
Clinical Trial Registries ◽  
Triple Antibiotic Paste ◽  
Post Operative Pain ◽  
Significant Difference

Background: This is a systematic review to assess and provide a pooled effect estimate, if possible, for the effects of triple antibiotic paste as an intra-canal medication for root canal treatment of mature permanent non-vital teeth with apical periodontitis. This review will assess post-operative pain, flare-up incidence, and clinical and radiographic healing. Methods: Nine electronic databases (Pubmed, CENTRAL, VHL, Scopus, EBSCOhost, Web of Science, Trip, OpenGrey, Proquest) were searched along with two major clinical trial registries. Conference proceedings, reference lists and citations of the included studies were also searched. A total of 537 records were identified and 392 were obtained after duplicate removal. Six records were identified after screening and three studies were included after full text eligibility assessment. Results:  Three comparators were reported in the included studies: calcium hydroxide paste, 2% chlorhexidine gel and ledermix paste.  There was no statistically significant difference between triple antibiotic paste and calcium hydroxide regarding postoperative pain, and clinical and radiographic healing of periapical lesions. There was no difference between triple antibiotic paste and chlorhexidine regarding flare-up incidence. However, triple antibiotic paste reduced the level of post-operative pain more than ledermix, which was statistically significant. Conclusions:  The evidence is still insufficient surrounding the use of triple antibiotic paste; therefore more clinical investigations with high levels of evidence and rigorous methodologies are needed.

scholarly journals Management of Large Periapical Cystic Lesion by Aspiration and Nonsurgical Endodontic Therapy using Calcium Hydroxide Paste

2012 ◽  
Vol 13 (6) ◽  
pp. 897-901 ◽  
Author(s):  
Kunjamma Thomas ◽  
T Prasanth Dhanapal ◽  
Elsy P Simon
Keyword(s):  
Calcium Hydroxide ◽  
Cystic Lesion ◽  
Additional Treatment ◽  
Radiographic Evaluation ◽  
Treatment Protocols ◽  
Maxillary Central Incisor ◽  
Periapical Lesions ◽  
Nonsurgical Management ◽  
Complications Of Surgery ◽  
Periapical Cyst

ABSTRACT Aim To report a case of conservative nonsurgical management of periapical lesions. Background Small periapical lesions of endodontic origin usually heal by conventional endodontic therapy alone. Larger periapical lesions presumed to be cystic may require additional treatment protocols to aid in regression. Conservative nonsurgical management of such lesions eliminates the possible complications of surgery and has wider patient compliance and acceptance. Case description A periapical cystic lesion associated with maxillary central incisor and lateral incisor was treated conservatively using buccal aspiration decompression followed by conventional endodontic therapy employing calcium hydroxide iodoform paste as intracanal medicament is reported. Clinical significance The treatment was successful as evidenced by relief of symptoms and radiographic evaluation. Conclusion Large periapical cyst-like lesions can resolve by nonsurgical endodontic therapy employing calcium hydroxide intracanal interappointment medicament. How to cite this article Thomas K, Dhanapal PT, Simon EP. Management of Large Periapical Cystic Lesion by Aspiration and Nonsurgical Endodontic Therapy using Calcium Hydroxide Paste. J Contemp Dent Pract 2012;13(6):897-901.

scholarly journals Erratum: Number of Dental Stem Cells on Root Canal Dentin after Application of Triple Antibiotic Paste or Calcium Hydroxide: An In Vitro Study

2019 ◽  
Vol 13 (02) ◽  
pp. e1-e1
Author(s):  
Konstantinos Gougousis ◽  
Dimitrios G. Giannakoulas ◽  
Vasiliki Taraslia ◽  
Anastasia Agrafioti ◽  
Ema Anastasiadou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
In Vitro Study ◽  
Vitro Study ◽  
Dental Stem Cells ◽  
Triple Antibiotic Paste ◽  
Root Canal Dentin

scholarly journals Assessment of Nitrofurantoin as an Experimental Intracanal Medicament in Endodontics

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Mewan Salahalddin A. Alrahman ◽  
Bestoon Muhammed Faraj ◽  
Kawa F. Dizaye
Keyword(s):  
Enterococcus Faecalis ◽  
Root Canal ◽  
Antibacterial Agent ◽  
Antibacterial Agents ◽  
Distilled Water ◽  
Human Teeth ◽  
Periapical Lesions ◽  
Complete Eradication ◽  
Colony Forming Unit ◽  
Triple Antibiotic Paste

Background and Objectives. Multiple antibacterial agents have been mixed and used as an intracanal medicament-like modified triple antibiotic paste (MTAP) to eliminate Enterococcus faecalis (EF), which has been most frequently identified in the cases of failed root canal treatment and periapical lesions. This study is aimed at using a single antibacterial agent, nitrofurantoin (Nit), as an experimental intracanal medicament paste against different clinical isolates of EF bacteria and at comparing its antimicrobial efficacy with MTAP. Materials and Methods. Three strains of EF (S1, S2, and S3) were clinically isolated. A total of 198 straight single-rooted human teeth were collected and divided randomly into three main groups: group N (Nit) (n=90), group M (MTAP) (n=90), and group W (distilled water) (n=18). The main groups were subdivided into three subgroups according to the strain of EF: in groups N and M, subgroups S1, S2, and S3 (n=30), while in group W, subgroups S1, S2, and S3 (n=6). Then, each subgroup of N and M was divided into five groups (n=6) according to the concentrations of Nit or MTAP (6.25, 12.5, 25, 50, and 100 mg/mL). The colony-forming unit (CFU) of EF from the canal lumen and dentinal chips was measured. Results. Nit could eradicate S1, S2, and S3 completely with concentrations of 6.25, 12.5, and 25 mg/mL, respectively, while MTAP showed complete eradication of the three strains only at 25 mg/mL. In all the groups, it was found that the CFU counts of EF in the dentinal chips were higher than those in the root canal lumen. Conclusion. At the concentration of 25 mg/mL, the Nit paste is effective in eradicating EF completely when it is used as an intracanal medicament.

scholarly journals Comparative Evaluation of the Interappointment Pain by Using Different Intracanal Medicaments—An In Vivo Study

2019 ◽  
Vol 07 (01) ◽  
pp. 019-022
Author(s):  
Varun Jindal ◽  
Sahil Monga ◽  
Deepti Jindal
Keyword(s):  
Calcium Hydroxide ◽  
Visual Analog Scale ◽  
Comparative Evaluation ◽  
Apical Periodontitis ◽  
In Vivo Study ◽  
Analog Scale ◽  
Cavity Preparation ◽  
Triple Antibiotic Paste

Abstract Objective The purpose of this in vivo study was to evaluate pain using different intracanal medicaments. Materials and Methods Seventy-five permanent single-rooted mandibular premolars with acute apical periodontitis were selected for this study. After access cavity preparation and cleaning and shaping of canals, patients were randomly divided into five groups with different intracanal medicaments viz calcium hydroxide paste, calcium hydroxide points, triple antibiotic paste, and Ledermix paste. Interappointment pain was recorded by the patient using visual analog scale after 6 hours, 12 hours, 18 hours, 24 hours, 2 days, 3 days, 4 days, 5 days, and 6 days of intracanal medicament dressing. Results Ledermix paste showed highly significant results in reducing the interappointment pain as compared with calcium hydroxide paste, calcium hydroxide points, and triple antibiotic paste. Conclusion Patients with Ledermix as intracanal medicament had minimum interappointment pain.

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