scholarly journals Lycopene Ameliorates Diabetic-Induced Changes in Erythrocyte Osmotic Fragility and Lipid Peroxidation in Wistar Rats

2017 ◽  
Vol 07 (03) ◽  
pp. 71-85 ◽  
Author(s):  
Ejike Daniel Eze ◽  
Yusuf Tanko ◽  
Ahmed Abubakar ◽  
Sheu Oluwadare Sulaiman ◽  
Karimah Mohammed Rabiu ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Wistar Rats ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility ◽  
Induced Changes

Erythrocyte osmotic fragility and lipid peroxidation in experimental hyperthyroidism

Endocrine ◽  
2009 ◽  
Vol 36 (3) ◽  
pp. 498-502 ◽  
Author(s):  
Rıfat Yücel ◽  
Semra Özdemir ◽  
Nuran Darıyerli ◽  
Selmin Toplan ◽  
M. Can Akyolcu ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Osmotic Fragility ◽  
Experimental Hyperthyroidism ◽  
Erythrocyte Osmotic Fragility

scholarly journals Enhanced calcium-sensitivity of erythrocytes in hypertension. Calcium-induced changes of erythrocyte osmotic fragility in essential hypertension.

1986 ◽  
Vol 50 (11) ◽  
pp. 1158-1164 ◽  
Author(s):  
Kazushi TSUDA ◽  
Yohsuke MINATOGAWA ◽  
Seiko FURUYA ◽  
Eizo UEDA ◽  
Yoshio KUSUYAMA ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Osmotic Fragility ◽  
Calcium Sensitivity ◽  
Erythrocyte Osmotic Fragility ◽  
Induced Changes

Vitamins C and E alone and in combination partly protect against chronic ethanol-induced toxicity in rat erythrocytes

2019 ◽  
Vol 89 (3-4) ◽  
pp. 152-160
Author(s):  
Parisa Hasanein ◽  
Peyman Mohammadi-Raighan ◽  
Alireza Komaki
Keyword(s):  
Lipid Peroxidation ◽  
Osmotic Fragility ◽  
Chronic Ethanol ◽  
Rat Erythrocytes ◽  
Beneficial Effects ◽  
Erythrocyte Osmotic Fragility ◽  
Ethanol Toxicity ◽  
Potential Alternative ◽  
And Control ◽  
Erythrocyte Fragility

Abstract. Oxidative stress is part of the mechanisms involved in ethanol toxicity. We investigated effects of vitamins C (VC), E (VE) and the combination of VC+VE on chronic ethanol-induced toxicity in rat erythrocytes. The following groups were treated for 30 days: control (C), VC (200 mg/kg), VE (200 mg/kg), VC (200 mg/kg) + VE (200 mg/kg), ethanol 4 g/kg, ethanol + VC, ethanol + VE and ethanol + VC + VE. The doses of vitamins and ethanol were selected for per kilogram of animal’s body weight. Blood samples collected at the end of treatments were analyzed for erythrocyte osmotic fragility and plasma scavenging activity. The washed erythrocytes were used to determine superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and malondialdeyde (MDA). Ethanol induced erythrocyte fragility (p < 0.001) and increased lipid peroxidation (p < 0.001) in rat erythrocytes. Furthermore, there were significant decreases in plasma scavenging (p < 0.001), SOD (p < 0.001), CAT (p < 0.01) and GPx (p < 0.001) activities in erythrocytes of ethanol-treated animals. Although VC or VE alone restored all of ethanol-induced disturbances to near normal (p > 0.05) but there were still significant differences compared to control animals. Combination therapy completely corrected ethanol-induced erythrocyte fragility, lipid peroxidation and prooxidant/antioxidant imbalance. We showed the beneficial effects of VC and VE combination in decreasing erythrocyte fragility and lipid peroxidation in both ethanol and control groups. Therefore this combination treatment may provide a new potential alternative for prevention of ethanol toxicity which deserves consideration and further examination.

Effect of zinc on erythrocyte osmotic fragility and hemogram following chronic exposure to glyphosate-based herbicide in Wistar rats

2019 ◽  
Vol 28 (5) ◽  
pp. 1275-1279
Author(s):  
Emmanuel Vandi Tizhe ◽  
Najume Dogon-Giginya Ibrahim ◽  
Mohammed Yakasai Fatihu ◽  
Suleiman Folorunsho Ambali ◽  
Ikechukwu Onyebuchi Igbokwe ◽  
...  
Keyword(s):  
Chronic Exposure ◽  
Wistar Rats ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility
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