scholarly journals Lead-induced increase in erythrocyte osmotic fragility and malondialdehyde concentration in Wistar rats: Chemo-protective effects of flavonoid mixture

2018 ◽  
Vol 6 (1) ◽  
pp. 9-14 ◽  
Author(s):  
I. L. Yusuf ◽  
◽  
I. O. Akefe ◽  
M. B. Tijjani ◽  
H. Yusuf ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Osmotic Fragility ◽  
Protective Effects ◽  
Erythrocyte Osmotic Fragility

scholarly journals Lycopene Ameliorates Diabetic-Induced Changes in Erythrocyte Osmotic Fragility and Lipid Peroxidation in Wistar Rats

2017 ◽  
Vol 07 (03) ◽  
pp. 71-85 ◽  
Author(s):  
Ejike Daniel Eze ◽  
Yusuf Tanko ◽  
Ahmed Abubakar ◽  
Sheu Oluwadare Sulaiman ◽  
Karimah Mohammed Rabiu ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Wistar Rats ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility ◽  
Induced Changes

Effect of zinc on erythrocyte osmotic fragility and hemogram following chronic exposure to glyphosate-based herbicide in Wistar rats

2019 ◽  
Vol 28 (5) ◽  
pp. 1275-1279
Author(s):  
Emmanuel Vandi Tizhe ◽  
Najume Dogon-Giginya Ibrahim ◽  
Mohammed Yakasai Fatihu ◽  
Suleiman Folorunsho Ambali ◽  
Ikechukwu Onyebuchi Igbokwe ◽  
...  
Keyword(s):  
Chronic Exposure ◽  
Wistar Rats ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility

Vitamin E protects Wistar rats from chlorpyrifos-induced increase in erythrocyte osmotic fragility

2010 ◽  
Vol 48 (12) ◽  
pp. 3477-3480 ◽  
Author(s):  
Suleiman Folorunsho Ambali ◽  
Joseph Olusegun Ayo ◽  
Samuel Adeniyi Ojo ◽  
King A. Nelson Esievo
Keyword(s):  
Vitamin E ◽  
Wistar Rats ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility

scholarly journals Co-Treatment of Purified Annatto Oil (Bixa orellana L.) and Its Granules (Chronic®) Improves the Blood Lipid Profile and Bone Protective Effects of Testosterone in the Orchiectomy-Induced Osteoporosis in Wistar Rats

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4720
Author(s):  
Arlindo César Matias Pereira ◽  
Helison de Oliveira Carvalho ◽  
Danna Emanuelle Santos Gonçalves ◽  
Karyny Roberta Tavares Picanço ◽  
Abrahão Victor Tavares de Lima Teixeira dos dos Santos ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Wistar Rats ◽  
Calcium Concentration ◽  
Calcium Content ◽  
Blood Lipid ◽  
Atomic Absorption Spectrophotometry ◽  
Protective Effects ◽  
Blood Lipid Profile ◽  
Bone Calcium ◽  
Weight Structure

This study aimed to evaluate and compare the effects of co-treatment with purified annatto oil (PAO) or its granules (GRA, Chronic®) with that of testosterone on the orchiectomy-induced osteoporosis in Wistar rats. After surgery, rats were treated from day 7 until day 45 with testosterone only (TES, 7 mg/kg, IM) or TES + PAO or GRA (200 mg/kg, p.o.). The following parameters were evaluated: food/water intake, weight, HDL, LDL, glucose, triglycerides (TG), total cholesterol (TC), alkaline phosphatase levels, blood phosphorus and calcium contents, femur weight, structure (through scanning electron microscopy), and calcium content (through atomic absorption spectrophotometry). Our results show that orchiectomy could significantly change the blood lipid profile and decrease bone integrity parameters. Testosterone reposition alone could improve some endpoints, including LDL, TC, bone weight, and bone calcium concentration. However, other parameters were not significantly improved. Co-treatment with PAO or GRA improved the blood lipid profile and bone integrity more significantly and improved some endpoints not affected by testosterone reposition alone (such as TG levels and trabeculae sizes). The results suggest that co-treatment with annatto products improved the blood lipid profile and the anti-osteoporosis effects of testosterone. Overall, GRA had better results than PAO.

scholarly journals Minor Changes in Erythrocyte Osmotic Fragility in Trace Amine-Associated Receptor 5 (TAAR5) Knockout Mice

2021 ◽  
Vol 22 (14) ◽  
pp. 7307
Author(s):  
Ilya S. Zhukov ◽  
Larisa G. Kubarskaya ◽  
Inessa V. Karpova ◽  
Anastasia N. Vaganova ◽  
Marina N. Karpenko ◽  
...  
Keyword(s):  
Knockout Mice ◽  
Emotional Regulation ◽  
Complete Blood Count ◽  
Gene Knockout ◽  
Hematological Parameters ◽  
Osmotic Fragility ◽  
Erythrocyte Osmotic Fragility ◽  
Trace Amine ◽  
Socially Relevant ◽  
The Impact

Trace amine-associated receptors (TAARs) are a group of G protein-coupled receptors that are expressed in the olfactory epithelium, central nervous system, and periphery. TAAR family generally consists of nine types of receptors (TAAR1-9), which can detect biogenic amines. During the last 5 years, the TAAR5 receptor became one of the most intriguing receptors in this subfamily. Recent studies revealed that TAAR5 is involved not only in sensing socially relevant odors but also in the regulation of dopamine and serotonin transmission, emotional regulation, and adult neurogenesis by providing significant input from the olfactory system to the limbic brain areas. Such results indicate that future antagonistic TAAR5-based therapies may have high pharmacological potential in the field of neuropsychiatric disorders. TAAR5 is known to be expressed in leucocytes as well. To evaluate potential hematological side effects of such future treatments we analyzed several hematological parameters in mice lacking TAAR5. In these mutants, we observed minor but significant changes in the osmotic fragility test of erythrocytes and hematocrit levels. At the same time, analysis of other parameters including complete blood count and reticulocyte levels showed no significant alterations in TAAR5 knockout mice. Thus, TAAR5 gene knockout leads to minor negative changes in the erythropoiesis or eryptosis processes, and further research in that field is needed. The impact of TAAR5 deficiency on other hematological parameters seems minimal. Such negative, albeit minor, effects of TAAR5 deficiency should be taken into account during future TAAR5-based therapy development.

Effects of melatonin on cloacal temperature and erythrocyte osmotic fragility in layer hens during the hot-dry season

2014 ◽  
Vol 43 (1) ◽  
pp. 52-60 ◽  
Author(s):  
Victor Olusegun Sinkalu ◽  
Joseph Olusegun Ayo ◽  
Ariyo Adelaja Abimbola ◽  
Josiah Egbamushe Ibrahim
Keyword(s):  
Osmotic Fragility ◽  
Dry Season ◽  
Erythrocyte Osmotic Fragility ◽  
Hot Dry Season ◽  
Layer Hens
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