scholarly journals The <i>in Vivo</i> Antioxidant Effects of (&minus;)-Epigallocatechin-3-Gallate Consumption in Healthy Postmenopausal Women Measured by Urinary Excretion of Secondary Lipid Peroxidation Products

2019 ◽  
Vol 10 (01) ◽  
pp. 15-27
Author(s):  
Chelsey Fiecke ◽  
Mindy Kurzer ◽  
Chi Chen ◽  
A. Saari Csallany
Keyword(s):  
Lipid Peroxidation ◽  
Urinary Excretion ◽  
Postmenopausal Women ◽  
Lipid Peroxidation Products ◽  
Antioxidant Effects

scholarly journals α-Tocopherol Influences in Vivo Indices of Lipid Peroxidation in Postmenopausal Women Given Fish Oil

1996 ◽  
Vol 126 (3) ◽  
pp. 643-652 ◽  
Author(s):  
Rosemary C. Wander ◽  
Shi-Hua Du ◽  
Sharon O. Ketchum ◽  
Kenneth E. Rowe
Keyword(s):  
Lipid Peroxidation ◽  
Fish Oil ◽  
Postmenopausal Women

scholarly journals Effect of short-term fasting on urinary excretion of primary lipid peroxidation products and on markers of oxidative DNA damage in healthy women

2006 ◽  
Vol 27 (7) ◽  
pp. 1398-1403 ◽  
Author(s):  
Kyoung-Ho Lee ◽  
Helmut Bartsch ◽  
Jagadeesan Nair ◽  
Dong-Ho Yoo ◽  
Yun-Chul Hong ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Dna Damage ◽  
Urinary Excretion ◽  
Oxidative Dna Damage ◽  
Short Term ◽  
Lipid Peroxidation Products ◽  
Healthy Women

scholarly journals A Diet with 3% of Energy from a Mixture of Omega-3 Fatty Acids Significantly Increases <i>in Vivo</i> Lipid Peroxidation in Postmenopausal Women

2016 ◽  
Vol 07 (12) ◽  
pp. 1099-1111
Author(s):  
A. Saari Csallany ◽  
Cheryl E. Ainslie-Waldman ◽  
Lindsay R. Young ◽  
Chi Chen ◽  
Mindy S. Kurzer ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Fatty Acids ◽  
Postmenopausal Women ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals A REVIEW ON ANTIOXIDANT METHODS

2016 ◽  
pp. 14 ◽  
Author(s):  
Dontha Sunitha
Keyword(s):  
Reactive Oxygen Species ◽  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Free Radical ◽  
Oxygen Species ◽  
Antioxidant Assay ◽  
Antioxidant Effects ◽  
In Vitro Antioxidant Activity

<p>ABSTRACT<br />To provide an outlook of the various available methods of antioxidant activity. Various available in vitro and in vivo methods are listed and the<br />procedure to perform the method, its mechanism is also explained in brief. 1,1-diphenyl-2-picrylhydrazyl method was found to be used mostly for the<br />in vitro antioxidant activity evaluation purpose while lipid peroxidation was found as mostly used in vivo antioxidant assay. An ethanol was with the<br />highest frequency as a solvent for extraction purpose. Summarized information on the various methods available provides with reliable information<br />to confirm the benefits of antioxidant effects.<br />Keywords: Antioxidant activity, Reactive oxygen species, Free radical, 1,1-diphenyl-2-picrylhydrazyl, Flavonoid.</p>

Effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics and sodium homoeostasis in cirrhotic patients with refractory ascites

1999 ◽  
Vol 96 (5) ◽  
pp. 467-474 ◽  
Author(s):  
Florence WONG ◽  
Arieh BOMZON ◽  
Johane ALLARD ◽  
Peter LIU ◽  
Laurence BLENDIS
Keyword(s):  
Lipid Peroxidation ◽  
Liver Function ◽  
Ursodeoxycholic Acid ◽  
Sodium Excretion ◽  
Refractory Ascites ◽  
Sodium Retention ◽  
Lipid Peroxidation Products ◽  
Cirrhotic Patients ◽  
Antioxidant Effects ◽  
Sodium Handling

Systemic arterial vasodilatation has been implicated in the pathogenesis of sodium retention in cirrhosis. Hydrophobic bile acids, which have vasodilatory actions, may be involved. Ursodeoxycholic acid, a hydrophilic bile acid, could potentially decrease systemic arterial vasodilatation, possibly due to its antioxidant effects, and improve sodium handling in cirrhosis. The effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics, liver function and renal sodium handling were assessed in vasodilated cirrhotic patients with refractory ascites treated with a transjugular intrahepatic porto-systemic shunt (TIPS). Eight cirrhotic patients with refractory ascites without TIPS placement served as controls for the sodium handling effects of ursodeoxycholic acid. From 1 month post TIPS, seven patients were studied before, after 1 month of treatment with ursodeoxycholic acid (15 mg·day-1·kg-1) and at 1 month follow-up. Lipid peroxidation products were used as indices of its antioxidant effects. Ursodeoxycholic acid caused a significant reduction in sodium excretion in both groups (P< 0.05). This, in the post-TIPS patients (urinary sodium excretion: 35±8 mmol/day at 1 month versus 93±21 mmol/day at baseline, P< 0.05), was due to a significant increase in sodium reabsorption proximal to the distal tubule (P< 0.05), without any significant changes in systemic, renal or forearm haemodynamics, or in liver function. No significant change in lipid peroxidation products was observed. We conclude that: (i) in cirrhotic patients with refractory ascites, ursodeoxycholic acid causes sodium retention, (ii) the abnormality in sodium handling in the post-TIPS cirrhotic patients appears to be the result of a direct effect on the proximal nephron, suggesting that factors other than systemic vasodilatation also contribute to sodium retention in cirrhosis, (iii) caution should be exercised in administering ursodeoxycholic acid in cirrhotic patients with ascites.

scholarly journals Enhanced Lipid Peroxidation in Patients Positive for Antiphospholipid Antibodies

Blood ◽  
1997 ◽  
Vol 90 (10) ◽  
pp. 3931-3935 ◽  
Author(s):  
Luigi Iuliano ◽  
Domenico Praticò ◽  
Domenico Ferro ◽  
Valerio Pittoni ◽  
Guido Valesini ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lipid Peroxidation ◽  
Urinary Excretion ◽  
Lupus Erythematosus ◽  
Antiphospholipid Antibodies ◽  
Previous History ◽  
Oxidation Products ◽  
Systemic Lupus ◽  
Highly Correlated

Abstract The mechanism leading to the formation of antiphospholipid antibodies (aPL) is still unknown. Because an in vitro study suggested that aPL may derive from pro-oxidant conditions, we sought a relationship between aPL and isoprostanes, indices of lipid peroxidation in vivo. Thirty patients with systemic lupus erythematosus have been studied. Seventeen (56.6%) were positive for aPL because they had lupus anticoagulant and/or high titer of anticardiolipin antibodies (aCL). Plasma levels of tumor necrosis factor (TNF ) and urinary excretion of two isoprostanes, 8-epi-PGF2α and IPF2α -I, free radical catalyzed oxidation products of arachidonic acid, were measured. Patients with systemic lupus erythematosus had higher urinary excretion of 8-epi-PGF2α and IPF2α -I than controls; urinary excretion of the two isoprostanes was highly correlated (Rho = 0.74, P < .0001). Urinary 8-epi-PGF2α was highly correlated with both aCL titer (Rho = 0.70, P < .0001) and TNF (Rho = 0.84, P < .0001), a measure of disease severity. Excretion of this isoprostane was also higher in those patients who exhibited aPL (P < .0001). Comparable correlations were observed with the isoprostane IPF2α -I. No difference of 8-epi-PGF2α was observed between patients with and without previous history of thrombosis. This study, showing the existence of a close association between aPL and increased in vivo lipid peroxidation, supports the hypothesis that these antibodies may result from pro-oxidative conditions and suggests that inflammation may play an important role.

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