scholarly journals Long-Term Treatment with an Herbal Formula MCC Ameliorates Obesity-Associated Metabolic Dysfunction in High Fat Diet-Induced Obese Mice: A Comparative Study among MCC and Various Combinations of Its Constituents

2014 ◽  
Vol 05 (01) ◽  
pp. 34-46 ◽  
Author(s):  
Pou Kuan Leong ◽  
Hoi Yan Leung ◽  
Hoi Shan Wong ◽  
Ji Hang Chen ◽  
Wing Man Chan ◽  
...  
Keyword(s):  
Comparative Study ◽  
High Fat Diet ◽  
Term Treatment ◽  
Herbal Formula ◽  
Metabolic Dysfunction ◽  
Obese Mice ◽  
High Fat ◽  
Long Term Treatment

scholarly journals Long-Term Treatment with an Herbal Formula MCC Reduces the Weight Gain in High Fat Diet-Induced Obese Mice

2013 ◽  
Vol 04 (03) ◽  
pp. 63-71 ◽  
Author(s):  
Pou Kuan Leong ◽  
Hoi Yan Leung ◽  
Hoi Shan Wong ◽  
Jihang Chen ◽  
Chung Wah Ma ◽  
...  
Keyword(s):  
Weight Gain ◽  
High Fat Diet ◽  
Term Treatment ◽  
Herbal Formula ◽  
Obese Mice ◽  
High Fat ◽  
Long Term Treatment

Extract of Schisandra chinensis fruit protects against metabolic dysfunction in high‐fat diet induced obese mice via FXR activation

2020 ◽  
Vol 34 (11) ◽  
pp. 3063-3077
Author(s):  
Ming Gu ◽  
Haiyan Song ◽  
Yiping Li ◽  
Yuwei Jiang ◽  
Yali Zhang ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Schisandra Chinensis ◽  
Metabolic Dysfunction ◽  
Obese Mice ◽  
High Fat

scholarly journals Long-Term Consumption of Platycodi Radix Ameliorates Obesity and Insulin Resistance via the Activation of AMPK Pathways

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Chae Eun Lee ◽  
Haeng Jeon Hur ◽  
Jin-Taek Hwang ◽  
Mi Jeong Sung ◽  
Hye Jeong Yang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
High Fat Diet ◽  
Adipocyte Differentiation ◽  
Cultured Cells ◽  
C2c12 Myotubes ◽  
Obese Mice ◽  
High Fat ◽  
Platycodi Radix ◽  
Chemotactic Protein

This study was designed to evaluate the effects and mechanism of Platycodi radix, having white balloon flower (Platycodon grandiflorum for. albiflorum (Honda) H. Hara) on obesity and insulin resistance. The extracts of Platycodi radix with white balloon flower were tested in cultured cells and administered into mice on a high-fat diet. The Platycodi radix activated the AMPK/ACC phosphorylation in C2C12 myotubes and also suppressed adipocyte differentiation in 3T3-L1 cells. In experimental animal, it suppressed the weight gain of obese mice and ameliorated obesity-induced insulin resistance. It also reduced the elevated circulating mediators, including triglyceride (TG), T-CHO, leptin, resistin, and monocyte chemotactic protein (MCP)-1 in obesity. As shown in C2C12 myotubes, the administration of Platycodi radix extracts also recovered the AMPK/ACC phosphorylation in the muscle of obese mice. These results suggest that Platycodi radix with white balloon flower ameliorates obesity and insulin resistance in obese mice via the activation of AMPK/ACC pathways and reductions of adipocyte differentiation.

Long-Term Treatment with a Yang-Invigorating Chinese Herbal Formula Produces Generalized Tissue Protection Against Oxidative Damage in Rats

2008 ◽  
Vol 11 (1) ◽  
pp. 43-62 ◽  
Author(s):  
Po Yee Chiu ◽  
Hoi Yan Leung ◽  
Ada Hoi Ling Siu ◽  
Na Chen ◽  
Michel K.T. Poon ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Term Treatment ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Tissue Protection ◽  
Long Term Treatment

Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice

2016 ◽  
Vol 36 (6) ◽  
pp. 1511-1518 ◽  
Author(s):  
Fabiano B. Calmasini ◽  
Mariana G. de Oliveira ◽  
Eduardo C. Alexandre ◽  
Fábio H. da Silva ◽  
Carmem P.V. da Silva ◽  
...  
Keyword(s):  
Detrusor Overactivity ◽  
Cyclic Adenosine Monophosphate ◽  
Adenosine Monophosphate ◽  
Term Treatment ◽  
Obese Mice ◽  
Adrenoceptor Agonist ◽  
Long Term Treatment ◽  
Camp Levels
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