Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice

2016 ◽  
Vol 36 (6) ◽  
pp. 1511-1518 ◽  
Author(s):  
Fabiano B. Calmasini ◽  
Mariana G. de Oliveira ◽  
Eduardo C. Alexandre ◽  
Fábio H. da Silva ◽  
Carmem P.V. da Silva ◽  
...  
Keyword(s):  
Detrusor Overactivity ◽  
Cyclic Adenosine Monophosphate ◽  
Adenosine Monophosphate ◽  
Term Treatment ◽  
Obese Mice ◽  
Adrenoceptor Agonist ◽  
Long Term Treatment ◽  
Camp Levels

Long-term clinical use of mirabegron in patients with overactive bladder syndrome

2020 ◽  
Vol 13 (4) ◽  
pp. 460-464
Author(s):  
Tomasz Wiatr ◽  
Piotr Chłosta
Keyword(s):  
Overactive Bladder ◽  
Term Treatment ◽  
Overactive Bladder Syndrome ◽  
Invasive Treatment ◽  
Treatment Development ◽  
Non Invasive ◽  
Antimuscarinic Drugs ◽  
Adrenoceptor Agonist ◽  
Long Term Treatment

Overactive bladder syndrome (OAB) is defined by the International Continence Society (ICS) as urinary urgency with increased daytime frequency and nocturia in the absence of proven infection or any other pathology, usually with or without urgency incontinence. Pharmacotherapy with antimuscarinic drugs is highly effective, but more than 60% of patients discontinue the treatment. Development of mirabegron, a β3-adrenoceptor agonist (β3-AR), has become an expected pharmacotherapy option for the non-invasive treatment of overactive bladder. The available studies show that long-term treatment with 50 mg mirabegron in patients with OAB is associated with reducing the severity of symptoms. Data from clinical trials show that mirabegron provides efficacy similar to antimuscarinic drugs, but with a better tolerance profile.

Long-term treatment with melatonin may increase anticontractile activity of perivascular fat in obese mice

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5686-P5686
Author(s):  
C. Agabiti Rosei ◽  
C. De Ciuceis ◽  
C. Rossini ◽  
E. Porteri ◽  
R. Rezzani ◽  
...  
Keyword(s):  
Term Treatment ◽  
Obese Mice ◽  
Long Term Treatment ◽  
Perivascular Fat

Anticontractile activity of perivascular fat in obese mice and the effect of long-term treatment with melatonin

2014 ◽  
Vol 32 (6) ◽  
pp. 1264-1274 ◽  
Author(s):  
Claudia Agabiti-Rosei ◽  
Carolina De Ciuceis ◽  
Claudia Rossini ◽  
Enzo Porteri ◽  
Luigi F. Rodella ◽  
...  
Keyword(s):  
Term Treatment ◽  
Obese Mice ◽  
Long Term Treatment ◽  
Perivascular Fat

scholarly journals Long-Term Treatment with an Herbal Formula MCC Reduces the Weight Gain in High Fat Diet-Induced Obese Mice

2013 ◽  
Vol 04 (03) ◽  
pp. 63-71 ◽  
Author(s):  
Pou Kuan Leong ◽  
Hoi Yan Leung ◽  
Hoi Shan Wong ◽  
Jihang Chen ◽  
Chung Wah Ma ◽  
...  
Keyword(s):  
Weight Gain ◽  
High Fat Diet ◽  
Term Treatment ◽  
Herbal Formula ◽  
Obese Mice ◽  
High Fat ◽  
Long Term Treatment

5.6 LONG-TERM TREATMENT WITH MELATONIN MAI IMPROVE ANTICONTRACTILE ACTIVITY OF PERIVASCULAR FAT IN OBESE MICE

2013 ◽  
Vol 7 (3-4) ◽  
pp. 169
Author(s):  
C. Agabiti Rosei ◽  
C. De Ciuceis ◽  
C. Rossiini ◽  
E. Porteri ◽  
R. Rezzani ◽  
...  
Keyword(s):  
Term Treatment ◽  
Obese Mice ◽  
Long Term Treatment ◽  
Perivascular Fat

Hypnotherapy is effective in the long-term treatment of functional dyspepsia

2001 ◽  
Vol 120 (5) ◽  
pp. A115-A115 ◽  
Author(s):  
E CALVERT ◽  
L HOUGHTON ◽  
P COOPER ◽  
P WHORWELL
Keyword(s):  
Functional Dyspepsia ◽  
Term Treatment ◽  
Long Term Treatment
Sign in / Sign up

Export Citation Format

Share Document