Usefulness of nasal provocation tests in occupational rhinitis

2009 ◽  
Vol 47 (4) ◽  
Author(s):  
F. Zerah-Lancer
Keyword(s):  
Occupational Rhinitis ◽  
Provocation Tests ◽  
Nasal Provocation

scholarly journals Nasal Provocation Test with Cat and Dog Extracts: Results according to Molecular Components

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Andres Sánchez ◽  
Ricardo Cardona ◽  
Marlon Munera ◽  
Victor Calvo ◽  
Manuela Tejada-Giraldo ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Clinical Symptoms ◽  
Provocation Test ◽  
Control Group ◽  
Nasal Provocation Test ◽  
Allergen Components ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Increased Risk ◽  
Can F 1

Background. IgE sensitization (atopy) to pets is commonly evaluated using pet dander extracts. However, the diagnosis by components seems to be more adequate to evaluate the clinical relevance (allergy) of sIgE sensitization. Objective. To study the association between IgE sensitization to pet allergen components and clinical symptoms. Methodology. Dander extracts and sIgE levels to pet components (Can f 1, Can f 2, Can f 3, Can f 5, Fel d 1, Fel 2, and Fel 4) were measured in a rhinitis group (n=101) and a control group (n=68). Nasal provocation tests with pet extract were done in patients with atopy to pets. Results. Dog (34.6% vs. 23.5%) and cat dander (26.7% vs. 8.8%, p=0.05) IgE sensitization was frequent among rhinitis and no-rhinitis subjects, and it was similar to dog (29.7% vs. 20.5%) and cat (18.8% vs. 8.8%) components. Polysensitization for dog (3.1, 95% CI: 1.5 to 6.1, p<0.001) or cat (2.5, 95% CI: 0.8 to 8.0, p=0.01) components was the principal risk factor for a positive nasal provocation test. Additionally, positive nasal provocation test with one animal increased the risk of atopy and positive nasal provocation test to others animals. Pet ownership or asthma was not associated with increased risk of atopy or positive nasal provocation test. Conclusions. Sensitization to pet dander extract identifies atopic patients, but its utility to predict clinical relevance is poor. Allergenic components could help to define the clinical relevance of sensitization to furry animals and could reduce the need for provocation test.

scholarly journals Detection of local allergic rhinitis in children with chronic, difficult‐to‐treat, non‐allergic rhinitis using multiple nasal provocation tests

2019 ◽  
Vol 30 (3) ◽  
pp. 296-304 ◽  
Author(s):  
Olympia Tsilochristou ◽  
Marialena Kyriakakou ◽  
Ioanna Manolaraki ◽  
John Lakoumentas ◽  
Ekaterini Tiligada ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Local Allergic Rhinitis ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Non Allergic Rhinitis

Nasal Provocation Tests With Allergens: Just a Research Tool or Suitable for Everyday Clinical Practice?

2017 ◽  
Vol 4 (1) ◽  
pp. 98-109 ◽  
Author(s):  
Paloma Campo ◽  
Esther Barrionuevo ◽  
Ibon Eguiluz ◽  
María Salas ◽  
M. José Torres ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Research Tool ◽  
Everyday Clinical Practice ◽  
Provocation Tests ◽  
Nasal Provocation

Acoustic Rhinometry in the Diagnosis of Occupational Rhinitis

1996 ◽  
Vol 10 (6) ◽  
pp. 393-398 ◽  
Author(s):  
Maija L Hytönen ◽  
Eeva L Sala ◽  
Henrik O Malmberg ◽  
Henrik Nordman
Keyword(s):  
Nasal Cavity ◽  
Provocation Test ◽  
Acoustic Rhinometry ◽  
Cross Sectional ◽  
Occupational Rhinitis ◽  
Limit Value ◽  
Provocation Tests ◽  
Calculated Parameter ◽  
Essential Change ◽  
The Mean

Acoustic rhinometry (ARM) has been used to study the nasal cavity geometry and the response in nasal provocations. However, the use of ARM in the diagnosis of occupational rhinitis (OR) has not been reported. The purpose of this study was to find an ARM parameter and a limit value that could be used in provocation tests to express an objective change in the nasal cavity geometry. We used a new calculated parameter, Volume MCA%, for describing the change in the nasal geometry. Volume MCA% is the mean of the percentile changes of nasal volumes and minimal cross-sectional areas in a provocation test. We recommend a decrease of at least 15% in Volume MCA% for the limit of an essential change in the nasal cavity.

Review of Symptoms Assessment During Nasal Allergen Provocation in Patients with Allergic Rhinitis

2010 ◽  
Vol 3 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Akli Zetchi ◽  
Marie-Claire Rousseau ◽  
Annie LeBlanc ◽  
Marie-Eve Boulay ◽  
Louis-Philippe Boulet
Keyword(s):  
Allergic Rhinitis ◽  
Animal Models ◽  
Therapy Monitoring ◽  
Literature Searching ◽  
Validation Process ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Nasal Symptoms ◽  
Allergen Provocation ◽  
Allergen Extracts

Background: Allergic rhinitis is the most prevalent allergic disease. Nasal provocation tests (NPTs) may be useful for its clinical diagnostic and therapy monitoring although they are mostly used in clinical research. However, the lack of standardisation in the symptoms assessed and the variety of instruments used make effective comparison between studies difficult. Objective: To review the published literature searching for instruments assessing nasal symptoms during NPTs for allergic rhinitis. Methods: Pubmed and Embase electronic databases were reviewed, looking for all methods including an instrument assessing symptoms during or following NPTs. Studies on animal models, pediatric subjects, and patients without allergic rhinitis were excluded. Studies were also excluded if they did not assess nasal symptoms during or following the NPT. Only NPT studies performed with allergen extracts or histamine were included. Results: A total of 520 studies were retrieved, from which 81 different instruments from 81 studies were included in the present analysis. There was no instrument reporting a validation process for the assessment of symptoms during NPTs. From the remaining instruments, the most common symptoms assessed were rhinorrhea (67), sneezing (70), congestion (67), and nasal pruritus (50). The most frequently used type of scales among those instruments was the four-point Likert scale (39), although different methods were used. Conclusions: This review illustrates the large variety of symptoms and methods used to assess the aforementioned NPTs. The lack of validation studies suggests the need to develop and validate a standardized instrument assessing symptoms following NPTs.

Nasal Provocation Tests

2019 ◽  
pp. 123-126
Author(s):  
Duygu Zorlu ◽  
Nuray Bayar Muluk ◽  
Paloma Campo
Keyword(s):  
Provocation Tests ◽  
Nasal Provocation

Optical rhinometry: Application on children and adolescents for nasal provocation tests

2007 ◽  
Vol 18 (5) ◽  
pp. 372-377 ◽  
Author(s):  
Holger Mittenzwey ◽  
Eike Gunther Wüstenberg ◽  
Wolfgang Leupold
Keyword(s):  
Children And Adolescents ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Optical Rhinometry
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