scholarly journals Influence of Yeast Extract on the Cytotoxicity of PSL Nanoparticles and Adhesion Force Measurement between a Nanoparticle and a Cell Using AFM

2016 ◽  
Vol 53 (12) ◽  
pp. 762-767 ◽  
Author(s):  
Shohei Yumiyama ◽  
Eri Fujisawa ◽  
Shunsuke Toyoda ◽  
Yuta Kuriyama ◽  
Yasuhiro Konishi ◽  
...  
Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 577
Author(s):  
Ashwini Shinde ◽  
Kavitha Illath ◽  
Pallavi Gupta ◽  
Pallavi Shinde ◽  
Ki-Taek Lim ◽  
...  

Cells exert, sense, and respond to the different physical forces through diverse mechanisms and translating them into biochemical signals. The adhesion of cells is crucial in various developmental functions, such as to maintain tissue morphogenesis and homeostasis and activate critical signaling pathways regulating survival, migration, gene expression, and differentiation. More importantly, any mutations of adhesion receptors can lead to developmental disorders and diseases. Thus, it is essential to understand the regulation of cell adhesion during development and its contribution to various conditions with the help of quantitative methods. The techniques involved in offering different functionalities such as surface imaging to detect forces present at the cell-matrix and deliver quantitative parameters will help characterize the changes for various diseases. Here, we have briefly reviewed single-cell mechanical properties for mechanotransduction studies using standard and recently developed techniques. This is used to functionalize from the measurement of cellular deformability to the quantification of the interaction forces generated by a cell and exerted on its surroundings at single-cell with attachment and detachment events. The adhesive force measurement for single-cell microorganisms and single-molecules is emphasized as well. This focused review should be useful in laying out experiments which would bring the method to a broader range of research in the future.


Nanoscale ◽  
2020 ◽  
Vol 12 (27) ◽  
pp. 14573-14580
Author(s):  
Min Xu ◽  
Xueyan Feng ◽  
Feng Feng ◽  
Hantao Pei ◽  
Ruping Liu ◽  
...  

Interactions of magnetic nanoparticles with cells were investigated from a cell mechanics perspective, and magnetic nanoparticle-based force spectroscopy was developed as a novel method to measure the adhesion force among various cancer cell lines.


2017 ◽  
Vol 37 (1) ◽  
pp. 102-111 ◽  
Author(s):  
Yu Hou ◽  
Zuobin Wang ◽  
Dayou Li ◽  
Renxi Qiu ◽  
Yan Li ◽  
...  

2005 ◽  
Vol 502 ◽  
pp. 327-334
Author(s):  
Kunio Takahashi

Author has been working about mechanisms of some manipulation methods for micro-assembly, i.e., a mechanical method, an electro-adhesive method, and a capillary method. For the purpose of optimization and breakthrough of the micro-assembly technology, theoretical understanding of adhesion phenomenon is essential, because the adhesional force is proportional to the size of objects meanwhile gravitational force is proportional to the third power of it. Consequently the adhesion phenomenon is no more negligible for the smaller objects usually less than 1 mm, e.g., micro-objects. Author will introduce our analyses about the manipulation mechanisms and related basic approaches to the adhesion phenomena including an adhesion force measurement in Auger electron spectroscope, an elastic continuum approximation approach using contact mechanics, a quantum mechanics approach for surface energy, a molecular mechanics approach for surface and interfacial energies. Also it will be expressed that our data base project for the surface and interfacial energies is based on these basic approaches for the purpose of optimization and/or breakthrough of the micro-assembly technology.


Author(s):  
Paul Weafer ◽  
Maarten H. van Es ◽  
Suzanne P. Jarvis ◽  
Patrick J. McGarry

Mechanical forces play a critical role in the regulation of cell spreading and cytoskeletal organization. It has been demonstrated that the force required to compress a spread cell is significantly higher than that required to compress a cell with a rounded morphology [1]. This increase in force can not be attributed to morphological changes alone [2], highlighting the importance of cytoskeletal remodeling during cell spreading in the resistance of cells to compressive forces.


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