Apparent absorption and retention of nutrients during the postweaning period in sows fed supplemental fat or lysine

1994 ◽  
Vol 74 (1) ◽  
pp. 123-128 ◽  
Author(s):  
R. R. Grandhi

A total of 36 first-parity Landrace × Yorkshire sows and 17 second-parity Yorkshire sows were used in separate metabolism trials of a 2 × 3 factorial design with two lactation (21–d) weight-loss groups and three postweaning treatment diets to determine the effect of feeding supplemental fat or lysine on apparent absorption and retention of nutrients during the postweaning period. Following a 5-wk lactation, sows were housed in individual sow metabolism stalls equipped for separate collection of feces and urine. The three treatment diets fed during the postweaning period were (1) control — a barley – canola meal gestation diet (12.4 MJ DE, 4.7 g lysine kg−1, and 12% protein) fed 2 kg d−1, (2) fat — the control diet plus animal fat premix to provide approximately 50% more DE d−1, and (3) lysine — the control diet with supplemental lysine to provide approximately 50% more lysine d−1. Feeding supplemental fat increased (P < 0.05) fat absorption and energy retention in sows of both parities. Water intake and absorption were reduced by feeding supplemental fat in first-parity sows. Feeding supplemental lysine increased nitrogen absorption in first-parity sows. The absorption and retention of both Ca and P were also higher in first-parity sows fed supplemental fat or lysine. The results indicated that feeding supplemental fat or lysine during the postweaning period may improve the absorption and retention of certain nutrients in sows. Key words: Postweaning, sows, nutrients, absorption, retention

1988 ◽  
Vol 68 (3) ◽  
pp. 941-951 ◽  
Author(s):  
R. R. GRANDHI

Four experiments were conducted, using a total of 356 Landrace × Yorkshire crossbred gilts, to determine the influence of flushing, supplemental fat and supplemental lysine fed from puberty to breeding (exps. 1 and 2) and from puberty through early gestation (exps. 3 and 4) on the reproductive performance of gilts. All gilts were housed in total confinement and fed ad libitum a 16% protein swine grower diet until 150 d of age. The diet was then restricted to 2 kg d−1 until puberty. The treatment diets fed from puberty to breeding in exps. 1 and 2 were: (1) control, a 12% protein barley-soybean meal gestation diet fed at 2 kg d−1 (24.4 MJ DE d−1); (2) flushing, control diet fed at 3 kg d−1 (36.6 MJ DE d−1; (3) animal fat, control diet fed at 2 kg d−1 plus 622 g of fat premix (36.6 MJ DE d−1; and (4) lysine, control diet with supplemental lysine (14 g d−1) fed at 2 kg d−1 (24.4 MJ DE d−1). After breeding, all gilts were fed control diet at 2 kg d−1 until approximately 30 d at gestation. In exps. 3 and 4, the same treatment diets were used except flushing was omitted and they were fed from puberty to approximately 30 d of gestation. No significant differences (P > 0.05) among the treatment groups were found in any of the experiments for the number of corpora lutea and normal embryos, and ovarian, uterine, and fetal weights. In exp. 2, the embryo survival rate (%) was significantly lower (P < 0.05) in the flushing (81.7 ± 3.3) and animal fat (78.3 ± 3.3) groups than in the control (92.9 ± 3.0); however, the lysine (88.8 ± 3.5) group did not differ significantly from the other groups. The embryo survival rate was also reduced (P < 0.05) by supplemental fat (81.5 ± 2.7) when compared to the control (86.8 ± 3.0) and lysine (88.8 ± 2.7) diets in exp. 3 but not in exp. 4. The serum progesterone level (ng/mL−1) was lower (P < 0.05) in the animal fat group (4.1 ± 0.6) than in the control (6.3 ± 0.6) and lysine (6.1 ± 0.6) groups in exp. 4. However, progesterone level of allantoic fluid in exp. 4 and estrone sulfate levels of both serum and allantoic fluid in exps. 3 and 4 were similar for the three treatment groups. The overall results indicated that flushing, supplemental fat or supplemental lysine fed from puberty to breeding, and supplemental fat or supplemental lysine fed from puberty through early gestation did not improve the ovulation rate, embryo survival or fetal development in gilts. Key words: Ovulation rate, embryo survival, flushing, fat, lysine, hormones, gilts


1992 ◽  
Vol 72 (3) ◽  
pp. 679-690 ◽  
Author(s):  
R. R. Grandhi

The effects of feeding supplemental fat or lysine during the postweaning period on breeding and subsequent reproductive performance were determined in two experiments of a 2 × 3 factorial design, using 168 Landrace × Yorkshire first-parity (exp. 1) and 180 Yorkshire second-parity (exp. 2) sows. At the end of lactation, they were divided into two groups: LWL (< 14 kg) and HWL (> 14 kg) based on 3 wk lactation weight loss. The three experimental diets fed during the postweaning period were: (1) control; a 12% gestation diet fed 2 kg d−1 (24.7 MJ DE, 9.4 g lysine d−1); (2) Fat; control diet plus animal fat to provide approximately 50% more daily energy intake (37.0 MJ DE d−1); and (3) Lysine; control diet plus lysine to provide approximately 50% more daily lysine intake (14.4 g d−1). After breeding, all sows were fed the control diet at 2 kg d−1, and they were killed at 30 d of gestation to evaluate their reproductive performance. High weight loss during the lactation period increased the incidence of anestrus and reduced the pregnancy rate in first-parity sows. Feeding supplemental fat was beneficial in increasing the proportion of sows in estrus within 7 d postweaning and the pregnancy rates of first-parity sows with high lactation weight loss. Supplemental fat also had a beneficial effect on ovulation rate, the number of normal embryos, fetal survival and the fetal weights, whereas supplemental lysine improved only fetal weights. Feeding supplemental fat or lysine improved only ovulation rate in second-parity sows with high lactation weight loss. The results indicated that feeding supplemental fat or lysine can improve the postweaning reproductive performance of sows that had high weight and fat losses during lactation. Key words: Sows, estrus, ovulation, embryo survival, fat, lysine


Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 757
Author(s):  
Jennifer M. Monk ◽  
Wenqing Wu ◽  
Dion Lepp ◽  
K. Peter Pauls ◽  
Lindsay E. Robinson ◽  
...  

Cooked common beans (Phaseolus vulgaris) improve intestinal health in lean mice and attenuate intestinal dysbiosis and inflammation when consumed concurrent with obesity development. We determined the effects of a high-fat (HF) bean supplemented diet in mice with established obesity (induced by 12 weeks of HF diet (60% fat as kcal)) compared to obese mice consuming a HF or low-fat (LF) weight loss control diet. Obese C57BL/6 male mice remained consuming HF for eight weeks or were randomly switched from HF to an isocaloric HF with 15.7% cooked navy bean powder diet (HFàHFB) or LF (11% fat as kcal; HFàLF) (n = 12/group). HFàHFB improved the obese phenotype, including (i) fecal microbiome (increased Prevotella, Akkermansia muciniphila, and short-chain fatty acid levels), (ii) intestinal health (increased ZO-1, claudin-2, Muc2, Relmβ, and Reg3γ expression), and (iii) reduced adipose tissue (AT) inflammatory proteins (NFκBp65, STAT3, IL-6, MCP-1, and MIP-1α), versus HF (p < 0.05). Conversely, HFàLF reduced body weight and circulating hormones (leptin, resistin, and PAI-1) versus HF and HFàHFB (p < 0.05); however, AT inflammation and intestinal health markers were not improved to the same degree as HFàHFB (p < 0.05). Despite remaining on a HF obesogenic diet, introducing beans in established obesity improved the obese phenotype (intestinal health and adipose inflammation) more substantially than weight loss alone.


2003 ◽  
Vol 90 (6) ◽  
pp. 1071-1080 ◽  
Author(s):  
Samantha Kew ◽  
Edward S. Gibbons ◽  
Frank Thies ◽  
Gerald P. McNeill ◽  
Paul T. Quinlan ◽  
...  

The effects of altering the type of n-3 polyunsaturated fatty acid (PUFA) in the mouse diet on the ability of monocytes and neutrophils to perform phagocytosis were investigated. Male weanling mice were fed for 7 d on one of nine diets which contained 178 g lipid/kg and which differed in the type of n-3 PUFA and in the position of these in dietary triacylglycerol (TAG). The control diet contained 4·4 g α-linolenic acid/100 g total fatty acids. In the other diets, eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) replaced a proportion (50 or 100 %) of the α-linolenic acid, and were in the sn-2 or the sn-1(3) position of dietary TAG. There were significant increases in the content of n-3 PUFA in spleen-cell phospholipids when EPA or DHA was fed. These increases were largely independent of the position of EPA or DHA in dietary TAG except when EPA was fed at the highest level, when the incorporation was greater when it was fed in the sn-2 than in the sn-1(3) position. There was no significant effect of dietary DHA on monocyte or neutrophil phagocytic activity. Dietary EPA dose-dependently decreased the number of monocytes and neutrophils performing phagocytosis. However, when EPA was fed in the sn-2 position, the ability of active monocytes or neutrophils to engulf bacteria was increased in a dose-dependent fashion. This did not occur when EPA was fed in the sn-1(3) position. Thus, there appears to be an influence of the position of EPA, but not of DHA, in dietary TAG on its incorporation into cell phospholipids and on the activity of phagocytic cells.


2007 ◽  
Vol 12 (1) ◽  
pp. 47-52
Author(s):  
Drucy Borowitz ◽  
Michael W. Konstan ◽  
Anna O'Rourke ◽  
Morty Cohen ◽  
Leslie Hendeles ◽  
...  

BACKGROUND We sought to compare the differences of coefficient of fat absorption (CFA) and coefficient of nitrogen absorption (CNA) in healthy individuals and those with cystic fibrosis (CF) and to study the precision of CFA and CNA. METHODS Sixteen healthy and 23 subjects with CF and pancreatic insufficiency ate a high-fat, high-protein diet for 72 hours; stool was collected between blue food dye markers to determine CFA and CNA. Subjects with CF withheld pancreatic enzymes. Tests were repeated on 5 of the CF and 10 of the healthy subjects. RESULTS In healthy subjects, mean CFA was 93.5% ± 2.7%; mean CNA was 88.1% ± 5%. Median test-retest in 10 healthy subjects was +0.7% CFA (range, −8.1% to + 5.9%) and +0.9% CNA (range, −14.6% to +6.8%). For subjects with CF, mean CFA was 38.5% ± 14.7% and mean CNA was 52.2% ± 11.4%. Median test-retest change in 5 subjects with CF was −6.9% CFA (range, −19.7% to +42.8%) and +14.7% CNA (range, −6.4% to +42.8%). CONCLUSIONS CFA and CNA have inconsistent precision in CF. The limitations of CFA as a measure of steatorrhea correction in CF should be recognized in studies of pancreatic enzyme supplements.


2000 ◽  
Vol 83 (5) ◽  
pp. 561-568 ◽  
Author(s):  
C. Feillet-Coudray ◽  
C. Coudray ◽  
D. Bayle ◽  
E. Rock ◽  
Y. Rayssiguier ◽  
...  

There is a lack of agreement on index of Cu status and reliable and sensitive biomarkers are still required. The purpose of this present work was to assess in rats the sensitivity of diamine oxidase (DAO) activity, a recently proposed biomarker, to modifications in dietary Cu intake in comparison with other plasma biomarkers of Cu status. We also evaluated the effect of Cu dietary level on Cu and Zn intestinal absorption. Results showed that plasma Cu and plasma caeruloplasmin were significantly decreased at day 8 compared with the control group (7·4 mg Cu/kg diet) while DAO activity was significantly decreased at day 12 of the deficient diet (0·61 mg Cu/kg diet). Cu supplementation (35 mg Cu/kg diet) had no effect on any of the studied biomarkers of Cu status. In Cu-deficient rats plasma Cu and DAO activities were normalized 4 d after return to the control diet while caeruloplasmin was normalized later, at day 11. Apparent absorption values (%) of total Cu or65Cu isotope were significantly increased in the Cu-deficient rats compared with the other groups and similar in the control and the Cu-supplemented groups. The urinary excretion of total Cu or65Cu isotope were increased in the Cu-supplemented group compared with the other two groups. Both apparent absorption and urinary excretion of total Zn or67Zn isotope remained unchanged in the three experimental groups. In conclusion, DAO activity seemed to be less sensitive to Cu deficiency than plasma Cu or caeruloplasmin concentrations. The present study also showed a significant increase in Cu intestinal absorption with dietary Cu restriction but no decrease with Cu supplementation in the rat.


1992 ◽  
Vol 72 (1) ◽  
pp. 147-153 ◽  
Author(s):  
N. A. Cave ◽  
E. E. Farnworth ◽  
L. M. Poste ◽  
G. Butler ◽  
V. D. Burrows

The yolk lipid composition was determined and the sensory and internal quality evaluated for eggs obtained from hens at 8 and 15 m of age from two experiments. In exp. 1, in which naked oats replaced corn and soybean meal at levels of 0–800 g kg−1, there was a marked decrease in Roche yolk color at 8 mo, an increase in egg weight, and at 15 mo and a decrease in yolk flavor intensity with increasing level of oats. In exp. 2, there were four diets (0) a corn-soybean meal control, (876) a soybean-free naked oat alfalfa diet, (874) diet 876 supplemented with lysine and methionine and (691) diet 876 supplemented with canola meal. Haugh units were greater and yolk color less for supplemented naked oat diets versus the control diet. The yolk lipid content of sphingomyelin and sterols were higher than for the control diet. A yolk sulfury aroma was noted at 15 mo. At 8 mo, egg Haugh units were lower for the unsupplemented oat diet relative to the corn-soy diet. There were no other detrimental effects of oat diet on egg sensory quality. Other than a corrigible yolk color effect, egg quality traits do not limit the use of naked oats in poultry layer diets. Key words: Oats (naked), canola, egg internal quality, egg sensory quality, egg lipid composition, laying hen


2008 ◽  
Vol 53 (No. 2) ◽  
pp. 77-82 ◽  
Author(s):  
M. Lichovníková ◽  
L. Zeman ◽  
J. Jandásek

The objective of the experiment was to evaluate the effect of the feeding of 80 g/kg (R8) and 100 g/kg (R10) of untreated rapeseed (RS) on egg quality including sensory quality in comparison with a control diet without rapeseed (R0). The addition of iodine (I) was also evaluated (1 mg/kg (R10) vs. 3 mg/kg (R10+I)). “Double zero” RS was used. The contents of energy and crude protein were almost the same in the diets. Laying hybrid ISABROWN was used in the experiment. The quality of eggs was analyzed 11 times every 28 days, from 19 to 64 weeks of age. 30 eggs per each group were always analyzed. Boiled eggs were assessed twice around the peak of egg production. Egg weight decreased (<I>P</I> < 0.001) with the increased level of RS (62.9 g, 61.8 g and 60.7 g, respectively). A reduction in egg weight in R8 and R10 diets resulted in the lower weight of albumen and eggshells. The addition of I to R10 diet increased (<I>P</I> < 0.001) egg weight (62.1 g vs. 60.7 g). The yolk proportion in egg weight was the highest (26.0%, <I>P</I> < 0.001) and the albumen weight ratio was the lowest (64.2%, <I>P</I> < 0.001) in group R8. Iodine supplementation improved (<I>P</I> < 0.001) yolk weight (15.7 g vs. 15.3 g). The proportion of RS in the diet did not affect the eggshell strength. An increase in the level of I improved (<I>P</I> < 0.001) eggshell quality (strength 36.1 N vs. 34.0 N and thickness 0.386 mm vs. 0.363 mm). Taste and overall acceptability were lower (<I>P</I> < 0.05) in eggs of hens fed RS. The addition of I did not affect flavour, odour, taste or overall acceptability.


2011 ◽  
Vol 107 (5) ◽  
pp. 705-711 ◽  
Author(s):  
Caroline Richard ◽  
Patrick Couture ◽  
Sophie Desroches ◽  
Suzanne Benjannet ◽  
Nabil G. Seidah ◽  
...  

The mechanisms implicated in the LDL-cholesterol (LDL-C)-lowering effects of the Mediterranean-type diet (MedDiet) are unknown. The present study assessed the impact of the MedDiet consumed under controlled feeding conditions, with and without weight loss, on surrogate markers of cholesterol absorption, synthesis and clearance using plasma phytosterols, lathosterol and proprotein convertase subtilisin/kexin-9 (PCSK9) concentrations, respectively, in men with the metabolic syndrome. The subjects' diet (n19, 24–62 years) was first standardised to a baseline North American control diet (5 weeks) followed by a MedDiet (5 weeks), both under weight-maintaining isoenergetic feeding conditions. The participants then underwent a 20-week free-living energy restriction period (10 (sd3) % reduction in body weight,P < 0·01), followed by the consumption of the MedDiet (5 weeks) under controlled isoenergetic feeding conditions. The LDL-C-lowering effect of the MedDiet in the absence of weight loss ( − 9·9 %) was accompanied by significant reductions in plasma PCSK9 concentrations ( − 11·7 %,P < 0·01) and in the phytosterol:cholesterol ratio ( − 9·7 %,P < 0·01) compared with the control diet. The addition of weight loss to the MedDiet had no further impact on plasma LDL-C concentrations and on these surrogate markers of LDL clearance and cholesterol absorption. The present results suggest that the MedDiet reduces plasma LDL-C concentrations primarily by increasing LDL clearance and reducing cholesterol absorption, with no synergistic effect of body weight loss in this process.


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