LOW DIETARY ZINC INTAKE DURING PREGNANCY AND LACTATION OF GILTS. I. EFFECTS ON THE DAM

1986 ◽  
Vol 66 (1) ◽  
pp. 201-216 ◽  
Author(s):  
J. KALINOWSKI ◽  
E. R. CHAVEZ
Keyword(s):  
Serum Proteins ◽  
Normal Pregnancy ◽  
Skin Lesions ◽  
Feed Consumption ◽  
Weight Changes ◽  
Lower Plasma ◽  
Zinc Intake ◽  
High Incidence ◽  
Pregnancy And Lactation ◽  
Ad Libitum

Pairs of littermate gilts were fed semipurified diets (2 kg d−1) containing either 10 or 52 ppm Zinc (Zn) throughout pregnancy and the two first weeks of lactation (ad libitum). Low dietary Zn did not affect feed consumption or weight changes of gilts. Low-Zn gilts showed lower plasma Zn and alkaline phosphatase activity (APA) throughout gestation and lactation and lower iron (Fe) and copper (Cu) before the last third of pregnancy. Urinary Zn was very sensitive to low Zn intake. Plasma protein and ammonia (NH3) were not affected by treatment. One-half of the deficient gilts exhibited skin lesions. Low-Zn gilts showed prolonged and stressful parturition with high incidence of intrapartum mortality reflected in the number of stillbirths. Total liveweight of the litter at birth, 1 and 2 wk of age was lower in Zn-deficient gilts. Low Zn supply did not affect the protein content or the profiles of the serum proteins of colostrum or milk but did affect the mineral composition. Colostrum of low-Zn gilts showed higher Cu, Fe and manganese (Mn), whereas milk showed lower Zn and higher Cu. Results obtained emphasize the importance of Zn for a normal pregnancy, delivery and nursing performance of the gilt. Key words: Zinc, gilts, pregnancy, lactation, piglets

LOW DIETARY ZINC INTAKE DURING PREGNANCY AND LACTATION OF GILTS. II. EFFECTS ON THE OFFSPRING

1986 ◽  
Vol 66 (1) ◽  
pp. 217-227 ◽  
Author(s):  
J. KALINOWSKI ◽  
E. R. CHAVEZ
Keyword(s):  
Physiological Changes ◽  
Lower Body ◽  
Lower Plasma ◽  
Lung Weight ◽  
Zinc Intake ◽  
Lower Body Weight ◽  
High Incidence ◽  
Pregnancy And Lactation ◽  
Lowered Body ◽  
Overall Mortality

Zinc (Zn) depletion was induced in pregnant gilts by feeding a diet containing 10 mg kg−1 Zn from day 22 of pregnancy until day 14 of lactation. Offspring of depleted gilts were born with lowered body, liver and gut weights; augmented lung weight; reduced plasma Zn, copper (Cu), ammonia (NH3), and alkaline phosphatase activity (APA); reduced hematocrit; increased glucose and lactate. Delivery problems of the dam caused a high incidence of stillbirths due to intrapartum anoxia. During the first week of age, piglets from depleted gilts exhibited lower body weight and reduced viability; lower plasma Zn, APA and NH3. At 2 wk of age body and organ weights were not different from that of controls; overall mortality was higher; plasma Zn was lower but Cu was higher. Zn-depletion of the dam endangered the outcome of pregnancy and promoted physiological changes in the newborn that affected neonatal growth. Key words: Piglets, viability, hypoxia, zinc

EFFECT OF LOW DIETARY ZINC DURING LATE GESTATION AND EARLY LACTATION ON THE SOW AND NEONATAL PIGLETS

1984 ◽  
Vol 64 (3) ◽  
pp. 749-758 ◽  
Author(s):  
J. KALINOWSKI ◽  
E. R. CHAVEZ
Keyword(s):  
Late Gestation ◽  
Early Lactation ◽  
Weight Changes ◽  
Lower Plasma ◽  
Significant Treatment ◽  
Neonatal Piglets ◽  
Neonatal Life ◽  
Ad Libitum ◽  
Significant Treatment Difference ◽  
Weight Number

Twelve pregnant sows were fed semi-purified diets containing either 13 or 63 mg/kg zinc (Zn). The animals were fed the diets during the last 4 wk of pregnancy (2 kg/day) and the two first weeks of lactation (ad libitum). Reduced level of dietary Zn did not affect (P > 0.05) weight changes of sows and no difference (P > 0.05) in food intake occurred during the ad libitum phase of the experiment. Low Zn sows showed lower plasma Zn at 100 (125 vs. 157 g/dL) and 113 (93 vs. 127 g/dL) days of gestation and at 7 (65 vs. 133 g/dL)) and 14 (59 vs. 99 g/dL) days of lactation. The differences were significant (P < 0.01) only during lactation. Copper (Cu), iron (Fe) and ammonia (NH3) concentrations in plasma and alkaline phosphatase activity (APA) of plasma were not affected by treatment. Parturition lasted 2.08 h in control and 4.54 h in low Zn sows (P < 0.1). Zinc, Cu and protein content of colostrum and milk were similar between groups. Low dietary Zn had no effect on litter size, birth weight, number of stillbirths and mortality up to 2 wk of age. Liveweight at 7 days was significantly higher in piglets nursed by low Zn dams but at 14 days of age no significant treatment difference was found. Zinc, Cu Fe, NH3 concentrations in plasma and APA in plasma of piglets were not significantly different at birth or at 7 days of age. At 14 days of age only plasma Zn was significantly reduced (P < 0.05). Low supply of Zn to dams had no effect on the performance of piglets during neonatal life. Key words: Zinc, sows, pregnancy, lactation, piglets

Fine Structural Alterations in Thyroid Follicular Cells (FC) and Changes in Serum Thyroxine Produced by Feeding Polychlorinated Biphenyl (PCB) to Rats

1977 ◽  
Vol 35 ◽  
pp. 498-499
Author(s):  
W.T. Collins ◽  
Charles C. Capen ◽  
Louis Kasza
Keyword(s):  
Feed Efficiency ◽  
Polychlorinated Biphenyl ◽  
Serum Proteins ◽  
Skin Lesions ◽  
Hepatic Necrosis ◽  
Ultrastructural Changes ◽  
Lymphoid Tissues ◽  
Heat Transfer Fluids ◽  
Thyroid Follicular Cells ◽  
Peripheral Metabolism

The widespread contamination of the environment with PCB, a compound used extensively by industry in hydraulic and heat transfer fluids as well as plasticizers and solvents in adhesives and sealants, has resulted in detectable tissue levels in a large portion of the human population, domestic animals, and wildlife. Intoxication with PCB produces severe hepatic necrosis, degeneration of lymphoid tissues and kidney, skin lesions, decreased reproductive performance, reduced feed efficiency, and decreased weight gain. PCB also has been reported to reduce the binding of thyroid hormone to serum proteins and enhance the peripheral metabolism of thyroxine with increased excretion of thyroxine-glucuronide in the bile (Bastomsky, Endocrinology 95: 1150-1155, 1974).The objectives of this investigation were (1) to investigate the histopathologic, histochemical, and ultrastructural changes in thyroid FC produced by the acute (4 week) and chronic (12 week) administration of low (50 ppm) and high (500 ppm) doses of PCB to rats, (2) to correlate these alterations to changes in serum immunoreactive thyroxine concentration, and (3) to investigate the persistence of the effects of PCB on the thyroid gland.

EFFECT OF LOW ZINC INTAKE DURING PREGNANCY ON PLASMA PROLACTIN, PROGESTERONE, PROSTAGLANDIN, CORTISOL AND PROTEIN CONCENTRATIONS OF EWES DURING THE PERIPARTURIENT PERIOD

1986 ◽  
Vol 66 (3) ◽  
pp. 643-651 ◽  
Author(s):  
J. A. FITZGERALD ◽  
G. A. EVERETT ◽  
J. APGAR
Keyword(s):  
Plasma Concentrations ◽  
Normal Pregnancy ◽  
Late Gestation ◽  
Plasma Prolactin ◽  
Plasma Parameters ◽  
Zinc Intake ◽  
Periparturient Period ◽  
Prostaglandin F ◽  
The Mean ◽  
Pregnant Ewe

The effect of low dietary Zn intake upon several plasma endocrine and metabolic profiles was examined during late gestation in the ewe. Thirty adult, primiparous Finncross ewes were fed a low Zn diet with (+Zn, n = 14) or without (0Zn, n = 16) supplemental Zn in the drinking water starting day 1 of pregnancy. Although the mean prepartum progesterone and prolactin concentrations were lower (P < 0.05 and P < 0.01, respectively) in 0Zn than in +Zn ewes, the peak prolactin concentrations in 0Zn ewes at lambing were similar to +Zn ewes. Both basal and thyrotropin-releasing-hormone (TRH)-induced prolactin release were less (P < 0.01) in 0Zn ewes 2 d postpartum. Plasma concentrations of 13, 14-dihydro-15-keto prostaglandin F2α (PGFM) of ewes sampled within 45 min post-lambing were lower (P < 0.05) in 0Zn ewes. There was no difference in cortisol concentrations within 45 min after lambing between 0Zn and + Zn ewes. Plasma protein concentrations in 0Zn ewes were higher (P < 0.01) than those in +Zn ewes during pregnancy. In summary, these data show that low Zn intake in the pregnant ewe affected several endocrine and metabolic plasma parameters associated with normal pregnancy and parturition. Key words: Zinc, parturition, dystocia, feed intake, ovine

Factors limiting the intake of feed by sheep. I. The significance of palatability, the capacity of the alimentary tract to handle digesta, and the supply of glucogenic substrate.

1966 ◽  
Vol 17 (6) ◽  
pp. 939 ◽  
Author(s):  
RH Weston
Keyword(s):  
Acetic Acid ◽  
Propionic Acid ◽  
Polyvinyl Chloride ◽  
Dry Matter ◽  
Alimentary Tract ◽  
Control Period ◽  
Feed Consumption ◽  
Ad Libitum

Voluntary feed consumption (VFC) decreased when a quantity of the diet being consumed by the sheep was introduced into the rumen. On diets of lucerne hay, lucerne hay plus maize, wheaten hay, and wheaten straw, the decreases in VFC ranged from 90 to 110% of the quantity introduced intraruminally when this quantity varied from 20 to 60% of the VFC during control periods. When sheep consumed wheaten straw ad libitum, and a quantity of coarsely ground wheaten straw equal to 140% of the VFC during a control period was given intraruminally, VFC ceased and digesta accumulated in the rumen. VFC decreased when indigestible materials were introduced into the rumen. The voluntary consumption of lucerne hay decreased by 15% when sawdust was introduced into the rumen at a rate equivalent by weight to 17% of the VFC during a control period ; decreases of 7 and 9% were found when finely ground polyvinyl chloride was introduced at rates equivalent by weight to 25 and 50% respectively of VFC during control periods. The voluntary consumption of wheaten hay decreased by 16 and 19% when sawdust was introduced into the rumen at rates equivalent by weight to 25 and 18% respectively of VFC during control periods. Intraruminal infusions of acetic acid, propionic acid, or a mixture of acetic, propionic, and butyric acids providing 290–510 kcal of energy daily were accompanied by decreases in the voluntary consumption of lucerne hay and wheaten hay; the decreases ranged from 0.29 to 0.86 g dry matter per kcal of energy infused; similar decreases were obtained when propionic acid was infused into the abomasum of sheep given lucerne hay. The intake of lucerne hay was 9% higher when given alone than when supplemented with 6% propionic acid. The results are discussed in relation to factors limiting the intake of lucerne hay and wheaten hay.

Effects of nutrition in late pregnancy on subsequent milk production in Ewes

1970 ◽  
Vol 12 (1) ◽  
pp. 23-36 ◽  
Author(s):  
T. T. Treacher
Keyword(s):  
Milk Production ◽  
Dry Matter ◽  
Live Weight ◽  
Late Pregnancy ◽  
Lower Content ◽  
Weight Changes ◽  
Total Birth ◽  
Weight Gains ◽  
Ad Libitum ◽  
Voluntary Intake

SUMMARY1. Scottish Half-bred ewes carrying twin foetuses were fed individually to make live-weight gains in the last six weeks of pregnancy of (1) 20%, (2) 10% and (3) 0% of their live weight in week 14 of pregnancy. In lactation the ewes were fed ad libitum. The lambs were removed 12 to 16 hr after parturition and the ewes were machine-milked twice daily for the first six weeks of lactation.2. Total birth weights per ewe of twin lambs from the treatments were (1) 10·10 kg, (2) 9·44 kg and (3) 8·18 kg and differed significantly.3. The level and pattern of voluntary intake in lactation did not differ significantly between the treatments. Total dry-matter intakes in the six weeks of lactation were (1) 121·9 kg (2) 105·9 kg and (3) 109·5 kg.4. The pregnancy treatments affected the level of milk production and the shape of lactation curves. The total yields in the first six weeks of lactation were (1) 58·8 kg, (2) 43·5 kg and (3) 26·9 kg. Higher contents of fat and protein and the lower content of lactose in the milk from treatment-3 ewes on days 1 and 3 of lactation indicated a slower onset of lactation in these ewes. Between days 7 and 35 of lactation the contents of fat and SNF were lowest on treatment 3 but the differences were not significant.5. The live-weight changes in lactation, which were in inverse order to the gains in late pregnancy, were (1) 3·4 kg, (2) 5·5 kg and (3) 9·5 kg.

Mice with combined disruption ofGpx1andGpx2genes have colitis

2001 ◽  
Vol 281 (3) ◽  
pp. G848-G855 ◽  
Author(s):  
R. Steven Esworthy ◽  
Richard Aranda ◽  
Martín G. Martín ◽  
James H. Doroshow ◽  
Scott W. Binder ◽  
...  
Keyword(s):  
Growth Retardation ◽  
Mucosal Inflammation ◽  
Lipid Hydroperoxides ◽  
Myeloperoxidase Activity ◽  
Housing Conditions ◽  
Double Knockout ◽  
High Incidence ◽  
Inflammatory Bowel ◽  
Ad Libitum ◽  
Gpx Activity

Glutathione peroxidase (GPX)-1 and gastrointestinal (GI) epithelium-specific GPX (GPX-GI), encoded by Gpx1 and Gpx2, provide most GPX activity in GI epithelium. Although homozygous mice deficient in either the Gpx1 or Gpx2 gene appeared to be normal under standard housing conditions, homozygous mice deficient in both genes, double-knockout (KO) mice, had symptoms and pathology consistent with inflammatory bowel disease. These symptoms included a high incidence of perianal ulceration, growth retardation that started around weaning, and hypothermia that resembled that observed in calorie-restricted mice, even though the double-KO mice in our study were allowed to eat ad libitum. The growth retardation and hypothermia were components of cachexia, which is fatal in a high percentage of mice. Histological examination revealed that the double-KO mice had a high incidence of mucosal inflammation in the ileum and colon but not in the jejunum. Elevated levels of myeloperoxidase activity and lipid hydroperoxides were also detected in colon mucosa of these homozygous double-KO mice. These results suggest that GPX is essential for the prevention of the inflammatory response in intestinal mucosa.

scholarly journals Analisis Bobot Badan dan Karakteristik Semen Ayam Gaok Terseleksi Generasi ke-6

2020 ◽  
Vol 20 (2) ◽  
Author(s):  
Komarudin Komarudin ◽  
Tike Sartika ◽  
Tatan Kostaman ◽  
Soni Sopiyana ◽  
Hasnelly Zainal
Keyword(s):  
Body Weight ◽  
Feed Consumption ◽  
Male And Female ◽  
Female Line ◽  
Semen Volume ◽  
Male Line ◽  
Ad Libitum ◽  
Live Sperm ◽  
Semen Characteristic

ABSTRAK. Ayam Gaok merupakan salah satu rumpun ayam lokal yang memiliki potensi besar dikembangkan. Balai Penelitian Ternak (Balitnak) telah melakukan program seleksi pada ayam Gaok untuk menghasilkan bibit ayam lokal pedaging yang dipanen umur 10 minggu dan dapat dijadikan galur jantan (male line) yang akan disilangkan dengan ayam KUB yang merupakan galur betina (female line). Tujuan dari penelitian ini untuk mengetahui pertumbuhan bobot badan dan karakteristik semen ayam Gaok generasi ke-6 yang dipelihara di Balitnak. Sebanyak 211 ekor anak ayam Gaok umur satu hari dari generasi ke-6 dipelihara pada kandang koloni pada masa starter dan grower. Ayam dewasa dipelihara pada kandang individu. Pakan dan air minum diberikan ad libitum. Bobot badan ayam jantan dan betina pada umur 10 minggu masing-masing 1.075,26 ± 156,55 g (KK= 14,56 %) dan 868,25 ± 109,34 g (KK= 12,59 %). Rerata bobot badan jantan dan betina sudah mulai berbeda nyata (P0,05) pada saat ayam berumur lima minggu. Konsumsi dan konversi pakan sampai umur 10 minggu yakni masing-masing 2.801,61 g dan 2,99. Bobot badan ayam jantan dan betina pada umur 20 minggu masing-masing 2.354,01 ± 280,06 (KK= 11,90%) dan 1.646,5 ± 205,97 g (KK= 12,51%). Volume semen, konsentrasi, motilitas dan persentase sperma hidup ayam Gaok jantan pada umur delapan bulan masing-masing sebesar 0,4 ml, 3.927 × 106, 57,22 dan 62,5%. Bobot badan ayam Gaok umur 10 minggu menunjukkan hasil baik dengan variasi yang cukup seragam. Kuantitas dan kualitas semen ayam Gaok tergolong normal.  (Analysis of body weight and semen characteristic of 6th generation selected gaok chicken) ABSTRACT. Gaok chicken is one of local breed chicken which potentially to be developed. Indonesian Research Institute for Animal Production (IRIAP) have been executed selection program on Gaok chicken to obtain meat type local chicken which is harvested on 10 weeks old age and can be made as male line to be crossed with KUB chicken which is the female line. The objective of this study was to observe growth of body weight and characteristics of semen of Gaok chicken 6th generation which are raised in IRIAP. A number of 211 DOC Gaok chicken 6th generation were raised in colony cage in starter and grower periods. Mature chickens were kept in individual cages. Feed and water were given ad libitum. Body weight male and female at 10 weeks were 1,075.26 ±156.55 g (CV=14,56 %) and 868.25 ± 109.34 g (CV=12,59 %) respectively. Body weight on male and female were started significantly differ from five weeks (P0.05). Feed consumption and conversion for 10 weeks were 2,901.61 g and 2.99, respectively. Body weight male and female at 20 weeks were 2,354.01 ± 280.06 g (CV=11,90 %) and 1,646.5 ± 205.97 g (CV=12,51 %) respectively. Semen volume, concentration, motility and proportion of live sperm of male Gaok chicken were 0.4 ml, 3,927 × 106, 57,22 % and 62.5 %, respectively. 10th week body weight of Gaok chicken showed good results with uniform variation. Quantity and quality of Gaok chicken semen belonged to be normal.

Milk production from diets of silage and dried forage. 1. Effects of methods of processing dried grass and of including barley in the supplementation of grass silage given ad libitum

1976 ◽  
Vol 23 (2) ◽  
pp. 197-209 ◽  
Author(s):  
J. C. Tayler ◽  
K. Aston
Keyword(s):  
Energy Content ◽  
Live Weight ◽  
Experimental Period ◽  
Milk Composition ◽  
Weight Changes ◽  
Treatment Groups ◽  
Grass Silage ◽  
Digestible Organic Matter ◽  
Ad Libitum ◽  
Female Cattle

SUMMARY1. Young adult and adult British Friesian female cattle (heifers and cows) which were lactating were individually fed on diets of grass silage ad libitum with supplements of dried grass, dried grass/barley or barley/groundnut in two randomized block experiments.2. In Experiment I, equal quantities of dry matter (DM) as dried grass in the form of a wafer (W), cob (C) or pellet (P) were given with the silage during weeks 8 to 18 of lactation, to three groups of 12 heifers. Silage DM intakes were respectively 14·2, 14·3 and 15·8 ± 0·43 g/kg live weight per day (P<0·05). Milk yields were 14·0, 15·6, 16·7 ± 0·35 kg/day (P< 0·001). Milk composition and live-weight change did not differ significantly.3. In Experiment II, five treatment groups of heifers and cows were offered silage with equal amounts of a supplement of either dried grass pellets (treatment 1) or dried grass/barley in the ratios of 2: 1 (treatment 2), 1: 2 (treatment 3), or a barley/groundnut supplement (treatment 4). In treatment 5 the cattle received the same supplement as in treatment 4, but at a 10% higher level. Silage DM intakes for treatments 1 to 5 during lactation weeks 6 to 22 were 8·64, 8·94, 7·96, 6·96, 7·63 kg/day (1, 2>4, P<0·01; 2>5, P<0·05). The intake of digestible organic matter, milk yields and live-weight changes over the whole experimental period were not influenced significantly by treatments 1 to 4, but in treatment 5 the milk was significantly higher in fat, protein and energy content than in treatments 1 to 4. Blood composition was normal and did not differ markedly between treatments.

THE INFLUENCE OF EXOGENOUS GROWTH HORMONE ON OVULATION RATE IN GILTS

1988 ◽  
Vol 68 (4) ◽  
pp. 1097-1103 ◽  
Author(s):  
R. N. KIRKWOOD ◽  
P. A. THACKER ◽  
A. D. GOONERATNE ◽  
B. L. GUEDO ◽  
B. LAARVELD
Keyword(s):  
Growth Hormone ◽  
Crude Protein ◽  
Ovulation Rate ◽  
Daily Injection ◽  
Corpora Lutea ◽  
Blood Samples ◽  
High Incidence ◽  
Exogenous Growth ◽  
Ad Libitum

A total of 32 prepubertal gilts of Yorkshire and Landrace breeding were selected at 138 d and fed ad libitum a 16.2% crude protein diet formulated to provide 13.1 MJ DE kg−1. From selection until the end of second estrus, the gilts were exposed to a boar for 30 min d−1 to facilitate the detection of pubertal and second estrous periods. From 14 d after puberty, the gilts received daily injections of either porcine growth hormone at 90 μg kg−1 body weight (GH; n = 20) or vehicle (CT; n = 12) until 24 h after the onset of second estrus and were then killed 9 d later to determine ovulation rate. Gilts not displaying a second estrus by 24 day after puberty were considered anestrus and the injection regime was halted. Anestrous gilts were killed 30–32 d after puberty and their ovaries examined for the presence of corpora albicantia and the absence of corpora lutea. Blood samples were obtained from all gilts at 14, 17, and 20 d after puberty. There was no treatment effect on the duration of the estrous cycle (20.8 vs. 21.3 d for GH and CT, respectively), but while all CT gilts cycled normally, only 55% of the GH gilts had a second estrus (P < 0.01). In those gilts having a second estrus, the daily injection of growth hormone increased ovulation rate (14.3 vs. 12.4 for GH and CT respectively; P < 0.03). Serum type 1 insulin-like growth factor (IGF-1) concentrations were higher (P < 0.001) in GH than in CT gilts, but there was no difference between cycling and anestrous GH gilts. We suggest that the effect of growth hormone on ovulation rate was mediated by increased secretion of IGF-1. The etiology of the high incidence of anestrus is, however, not known. Key words: Gilts, growth hormone, ovulation rate

Sign in / Sign up

Export Citation Format

Share Document