POSTWEANING PERFORMANCE OF ARTIFICIALLY REARED LAMBS WEANED AT 21 VS. 28 DAYS OF AGE UNDER TWO POSTWEANING HOUSING REGIMENS

1984 ◽  
Vol 64 (3) ◽  
pp. 667-674 ◽  
Author(s):  
D. P. HEANEY ◽  
J. N. B. SHRESTHA ◽  
H. F. PETERS
Keyword(s):  
Key Words ◽  
Liquid Diet ◽  
Milk Replacer ◽  
Minor Importance ◽  
Artificial Rearing ◽  
Weaning Age ◽  
A Minor ◽  
The Cost

Lambs that had been artificially reared on either lamb milk replacer or calf milk replacer were weaned at 21 or 28 days of age. At weaning, lambs from each milk replacer were randomly assigned to two treatments: (1) transferred on the day weaned to a growing barn, and (2) retained in their liquid-diet pens to 49 days of age, then transferred. Delaying weaning from 21 to 28 days of age essentially eliminated the postweaning growth check for lambs artificially reared on lamb milk replacer and reduced the postweaning growth check for those reared on calf milk replacer. However, the resulting increase in liveweight at 70 days of age was not sufficient to offset the cost of the milk replacer required for the extra week on liquid diet. Postweaning location had only a minor and inconsistent effect on lamb performance indicating that, when facilities are satisfactory, postweaning location is of minor importance for artificially reared lambs. Key words: Lambs, artificial rearing, weaning age, postweaning location

POTENTIAL ALTERNATIVES TO LAMB MILK REPLACER FOR THE ARTIFICIAL REARING OF LAMBS

1982 ◽  
Vol 62 (4) ◽  
pp. 1135-1142 ◽  
Author(s):  
D. P. HEANEY ◽  
J. N. B. SHRESTHA ◽  
H. F. PETERS
Keyword(s):  
Key Words ◽  
Well Being ◽  
Cow Milk ◽  
Milk Replacer ◽  
Artificial Rearing ◽  
High Quality ◽  
Milk Products ◽  
Feed Costs ◽  
Spray Dried ◽  
General Appearance

Two experiments were conducted to evaluate the relative performance of artificially reared lambs fed four types of liquid diets: (1) lamb milk replacer (LMR) with 24% protein from spray-dried milk products and 24% fat in the dry powder; (2) high quality calf milk replacer (CMR) with 20% protein from spray-dried milk products and 20% fat; (3) fresh cow milk (CM); or (4) equal proportions of LMR and CM (LMR:CM). Average daily gains of lambs fed CMR or CM were lower by 16% and 12%, respectively, and weaning weights were lower by 10% and 5%, respectively, than those of lambs fed LMR. Gains and weaning weights of lambs fed LMR:CM were identical to those fed LMR. Lamb survival was marginally lower among CMR- and CM-fed lambs compared with those fed LMR. There were no observable differences among any of the feeding regimens in the general appearance, thriftiness or well-being of the lambs. The results indicate that, with good management, satisfactory lamb performance under artificial rearing can be achieved with high quality CMR or CM and that under practical conditions lower feed costs could offset the marginal reduction in lamb performance. Key words: Lambs, artificial rearing

PERFORMANCE OF YOUNG LAMBS FED A CLOTTING OR A NON-CLOTTING MILK REPLACER

1988 ◽  
Vol 68 (3) ◽  
pp. 993-996
Author(s):  
JOCELYNE DELISLE ◽  
HÉLÈNE V. PETIT ◽  
FRANCINE GIGUÈRE
Keyword(s):  
Key Words ◽  
Dry Matter ◽  
Room Temperature ◽  
Dry Matter Intake ◽  
Milk Replacer ◽  
Artificial Rearing ◽  
Ad Libitum ◽  
Milk Replacers

Sixteen male lambs weighing 2.8 – 5.8 kg and 3–5 d old were fed for 5 wk a clotting milk replacer with or without an oxalate-NaOH buffer known to prevent curd formation in the abomasum. Milk replacers were fed ad libitum at room temperature using formalin (0.1% vol vol−1) as preservative. Dry matter intake and average daily gains were the same (P > 0.05) for both the clotting and the nonclotting milk replacers. Digestibility of dry matter, nitrogen, and lipids was also similar (P > 0.05) for both treatments. Key words: Lambs, artificial rearing, milk replacer, clotting, coagulation, digestibility

RAPESEED OIL VERSUS COCONUT OIL AS A SOURCE OF FAT FOR LAMB MILK REPLACERS

1982 ◽  
Vol 62 (4) ◽  
pp. 1241-1243 ◽  
Author(s):  
D. P. HEANEY ◽  
J. N. B. SHRESTHA ◽  
H. F. PETERS
Keyword(s):  
Key Words ◽  
Rapeseed Oil ◽  
Dry Matter ◽  
Coconut Oil ◽  
Milk Replacer ◽  
Artificial Rearing ◽  
Lamb Survival ◽  
Milk Replacers

Artificially reared lambs were weaned from milk replacer (MR) at 21 days of age. Weaning weights and average daily gains were significantly (P < 0.01) depressed (7.6 and 18%, respectively) for lambs fed MR containing 12% rapeseed oil and 12% tallow compared with those fed a standard MR containing 12% coconut oil and 12% tallow. Lamb survival and MR dry matter consumption were similar for lambs fed the two diets. The results indicate that, under practical conditions, the use of rapeseed oil to provide half of the fat in lamb milk replacers causes a reduction in the performance of lambs artificially reared from birth. Key words: Artificial rearing, lambs, rapeseed oil

Dynamics of oxytocin, estrogen and progestin receptors in the bovine endometrium during the estrous cycle

1988 ◽  
Vol 118 (1) ◽  
pp. 96-104 ◽  
Author(s):  
H. H. D. Meyer ◽  
Th. Mittermeier ◽  
D. Schams
Keyword(s):  
Estrous Cycle ◽  
Luteal Phase ◽  
Oxytocin Receptor ◽  
Minor Importance ◽  
Progestin Receptors ◽  
Progestin Receptor ◽  
Nuclear Estrogen Receptor ◽  
Low Sensitivity ◽  
A Minor ◽  
Estradiol Levels

Abstract. The levels of oxytocin receptor (OTR), cytosolic progestin receptor (cPR), cytosolic and nuclear estrogen receptor (cER, nER) were measured in the endometrium of 28 heifers that had been slaughtered on a defined day of the estrous cycle, In an additional, trial endometrial tissue obtained from 78 heifers or cows at the abattoir was analyed for OTR. OTR was absent during the luteal phase (after day 6), but a minor elevation was observed after day 15. OTR increased rapidly after luteolysis on days 17–18 reaching a maximum during estrous on day 21, and decreased again during days 1–6. cER and cPR were different to OTR but followed a similar pattern with maximal levels during days 1–8 of the estrous cycle. At day 12 both receptors were minimal and increased again towards day 21. nER was maximal at day 19–21 coinciding with maximal estradiol levels and estrous. Our data indicate that owing to an increasing sensitivity of the endometrium to progesterone and estradiol after day 12, these steroids may be mainly responsible for the initiation of first PGF2α surges and luteolysis. Oxytocin seems to be of minor importance at this stage owing to low sensitivity of the endometrium for oxytocin.

Factors affecting the future of the Scottish hydrometric network

1987 ◽  
Vol 78 (4) ◽  
pp. 269-274 ◽  
Author(s):  
T. Poodle
Keyword(s):  
Data Acquisition ◽  
Computer Systems ◽  
Economic Recession ◽  
Data Standards ◽  
Factors Affecting ◽  
Economic Climate ◽  
A Minor ◽  
The Cost ◽  
Minor Extent

ABSTRACTThe Scottish Hydrometric Network consists of a number of river gauging stations which have been located at sites considered suitable to provide long term flow records. Economic recession has placed some stress on the gauging programme, and has given rise to extensive closures of gauging stations in England and, to a minor extent so far, in Scotland. The way in which the network became established provides a mixture of strengths and weaknesses which could have unpredictable consequences in an adverse economic climate. Changing technology provides some opportunity to reduce the cost of data acquisition and improve the deployment of manpower, while maintaining data standards. In these changing circumstances, particularly with extensive use of computer systems, it is important that standards are established for data returned to the Water Archive and that the network is not allowed to degenerate by default.

scholarly journals The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity

Blood ◽  
2010 ◽  
Vol 116 (16) ◽  
pp. 3064-3072 ◽  
Author(s):  
Rens de Groot ◽  
David A. Lane ◽  
James T. B. Crawley
Keyword(s):  
Single Point ◽  
Minor Importance ◽  
Variable Regions ◽  
Cleavage Efficiency ◽  
Scissile Bond ◽  
A Minor ◽  
Von Willebrand ◽  
A2 Domain ◽  
Willebrand Factor

Abstract ADAMTS13 modulates von Willebrand factor (VWF) platelet-tethering function by proteolysis of the Tyr1605-Met1606 bond in the VWF A2 domain. To examine the role of the metalloprotease domain of ADAMTS13 in scissile bond specificity, we identified 3 variable regions (VR1, -2, and -3) in the ADAMTS family metalloprotease domain that flank the active site, which might be important for specificity. Eight composite sequence swaps (to residues in ADAMTS1 or ADAMTS2) and 18 single-point mutants were generated in these VRs and expressed. Swapping VR1 (E184-R193) of ADAMTS13 with that of ADAMTS1 or ADAMTS2 abolished/severely impaired ADAMTS13 function. Kinetic analysis of VR1 point mutants using VWF115 as a short substrate revealed reduced proteolytic function (kcat/Km reduced by 2- to 10-fold) as a result of D187A, R190A, and R193A substitutions. Analysis of VR2 (F216-V220) revealed a minor importance of this region. Mutants of VR3 (G236-A261) proteolysed wild-type VWF115 normally. However, using either short or full-length VWF substrates containing the P1′ M1606A mutation, we identified residues within VR3 (D252-P256) that influence P1′ amino acid specificity, we hypothesize, by shaping the S1′ pocket. It is concluded that 2 subsites, D187-R193 and D252-P256, in the metalloprotease domain play an important role in cleavage efficiency and site specificity.

Home Enteral Tube Feeding with a Liquid Diet in the Long Term Management of Inflammatory Bowel Disease and Intestinal Failure

1980 ◽  
Vol 25 (4) ◽  
pp. 312-314 ◽  
Author(s):  
A. N. H. Main ◽  
R. J. Morgan ◽  
M. J. Hall ◽  
R. I. Russell ◽  
A. Shenkin ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Elemental Diet ◽  
Intestinal Failure ◽  
Tube Feeding ◽  
Liquid Diet ◽  
Intravenous Nutrition ◽  
Inflammatory Bowel ◽  
The Cost

A 35-year-old man, who had spent 10[Formula: see text] out of 18 months in hospital, has required repeated courses of intravenous nutrition (IVN) because of nutritional failure due to severe inflammatory bowel disease. He has been maintained on a nocturnal pump-fed liquid diet supplementing his day-time oral diet jar five months, four of which have been at home. The cost of such therapy is less than with an elemental diet and there are other advantages. This regime has been shown to be nutritionally adequate. The need to assess other cheaper liquid diets in patients with intestinal failure is recognised.

INHERITANCE OF WEIGHTS OF LAMBS REARED ARTIFICIALLY OR WITH THEIR DAMS

1983 ◽  
Vol 63 (2) ◽  
pp. 263-268 ◽  
Author(s):  
J. N. B. SHRESTHA ◽  
H. F. PETERS ◽  
D. P. HEANEY
Keyword(s):  
Genetic Correlation ◽  
Direct Selection ◽  
Milk Replacer ◽  
Response To Selection ◽  
Genetic Response ◽  
Artificial Rearing ◽  
Solid Diet ◽  
Selection For ◽  
Heritability Estimates ◽  
Age Estimates

This study involved 250 lambs reared artificially with milk replacer and solid diet from 2 to 70 days and 316 lambs creep-fed solid diet and reared with their dams from birth to 70 days. Thereafter, all lambs were retained on solid diet to 140 days of age. Heritability estimates for weights of lambs reared artificially tended to be larger than the corresponding estimates for lambs reared with their dams (P > 0.05). Phenotypic variances of lambs reared with their dams were larger at birth and at 35 days, whereas lambs reared artificially had larger phenotypic variances at 70 and 140 days of age. Estimates of genetic correlation between half-sib family means of lambs reared artificially with corresponding half-sibs reared with their dams ranged from 0.15 to 0.91, suggesting the absence of sire × rearing system interaction. We conclude that greater genetic response to selection for lamb weights at various ages could be achieved from direct selection among lambs reared artificially compared to those reared with their dams. However, in the absence of artificial rearing, prospective breeding stock reared with their dams should be tested for postweaning performance to permit full expression of transmitted sire differences. Key words: Sheep, lamb rearing, heritability estimates, genetic correlation

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